公开(公告)号：US11725221B2

公开(公告)日：2023-08-15

申请号：US16636940

申请日：2018-08-09

申请人： DSM IP Assets B.V. ,  Evonik Operations GMBH

发明人： Neil Francis Leininger ,  Holger Pfeifer ,  David Allen Tinsley ,  Jochen Lebert ,  Marc Beiser

IPC分类号： C12P7/6472 ,  A23L33/12 ,  A23D9/04 ,  B01D21/26 ,  C11B1/10

CPC分类号： C12P7/6472 ,  A23D9/04 ,  A23L33/12 ,  B01D21/262 ,  C11B1/10 ,  A23V2002/00

摘要： This invention relates to a method of using a two-step serial centrifugation process in extracting nutritive oil from a fermentation broth, this novel method prevents oil yield losses while preserving product quality.

公开(公告)号：US11352651B2

公开(公告)日：2022-06-07

申请号：US16473805

申请日：2017-12-20

申请人： EVONIK OPERATIONS GMBH ,  DSM IP ASSETS B.V.

发明人： Michael Diehl ,  Xiao Daniel Dong ,  Annika Hartmann ,  Martin Heining ,  Michael Benjamin Johnson ,  Jochen Lebert ,  Neil Francis Leininger ,  Kirt Lyvell Matthews, Sr. ,  Mark Edward Nejako, II ,  Holger Pfeifer ,  Christian Rabe ,  Shannon Elizabeth Ethier Resop ,  Ginger Marie Shank ,  Vinod Tarwade ,  David Allen Tinsley

IPC分类号： C12P7/64 ,  C11B1/10 ,  C12P7/6463

摘要： The invention relates to the isolation of polyunsaturated fatty acids (PUFAs) from a lipids containing biomass. The main characteristics of the method are that a suspension of cells containing PUFAs is obtained and the cells are optionally lysed. The suspension is concentrated and then incubated for at least an hour at a controlled temperature while adding a specific range of base equivalents to biomass and maintaining a moderate pH. The isolation of lipid may be performed in the absence of organic solvents and without the addition of salt.

公开(公告)号：US11946017B2

公开(公告)日：2024-04-02

申请号：US16317305

申请日：2017-07-12

申请人： Evonik Operations GmbH ,  DSM IP Assets B.V.

发明人： Manfred Bärz ,  Marc Beiser ,  Georg Borchers ,  Stephen Robert Cherinko ,  Mathias Dernedde ,  Michael Diehl ,  Xiao Daniel Dong ,  Jürgen Haberland ,  Michael Benjamin Johnson ,  Robert Cody Kertis ,  Jochen Lebert ,  Neil Francis Leininger ,  Kirt Lyvell Matthews, Sr. ,  Holger Pfeifer ,  Christian Rabe ,  Shannon Elizabeth Ethier Resop ,  Ginger Marie Shank ,  Vinod Tarwade ,  David Allen Tinsley ,  Daniel Verkoeijen

IPC分类号： C11B1/12 ,  A23K10/12 ,  A23K20/158 ,  C11B1/02

CPC分类号： C11B1/12 ,  A23K10/12 ,  A23K20/158 ,  C11B1/025

摘要： The current invention relates to a method of separating polyunsaturated fatty acids containing lipids from a lipids containing biomass.

公开(公告)号：US11542220B2

公开(公告)日：2023-01-03

申请号：US16956453

申请日：2018-12-18

申请人： EVONIK OPERATIONS GMBH ,  DSM IP ASSETS B.V.

发明人： Martin Heining ,  Michael Benjamin Johnson ,  Jochen Lebert ,  Holger Pfeifer

IPC分类号： C07C51/50

摘要： The current invention relates to a method of isolating polyunsaturated fatty acids containing lipids from a lipids containing biomass. The method involves providing a suspension of cells with a PUFAs-containing lipid; optionally lysing the cells; concentrating the suspension; adding base equivalents to the suspension based on the total dry matter present; feeding a continuous reactor with the suspension; and separating the lipids-containing light phase from the water and cell debris-containing heavy phase.

公开(公告)号：US11261400B2

公开(公告)日：2022-03-01

申请号：US16644443

申请日：2018-08-30

申请人： EVONIK OPERATIONS GMBH ,  DSM IP ASSETS B.V.

发明人： Michael Bahl ,  Marc Beiser ,  Jochen Lebert ,  Holger Pfeifer ,  Christian Rabe

IPC分类号： C11B1/02 ,  C11B1/04 ,  C11B1/10 ,  C11B7/00

摘要： The current invention relates to a method of separating polyunsaturated fatty acids containing lipids from a lipids containing biomass by using acetone.