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公开(公告)号：US20220274926A1
公开(公告)日：2022-09-01
申请号：US17552517
申请日：2021-12-16
发明人： Hilary Plake BECK , Juan Carlos JAEN , Maksim OSIPOV , Jay Patrick POWERS , Maureen Kay REILLY , Hunter Paul SHUNATONA , James Ross WALKER , Mikhail ZIBINSKY , James Aaron BALOG , David K. WILLIAMS , Weiwei GUO
IPC分类号： C07D213/75 , A61K45/06 , A61K31/167 , C07C255/60 , C07C317/40 , C07D239/42 , C07C233/15 , C07D295/155 , C07C233/29 , C07C237/22 , C07C233/66 , C07D213/56 , C07C321/28 , C07D295/15 , C07C235/26 , A61K31/195 , C07C255/57 , C07C235/38 , C07D207/27 , C07D231/12 , C07C317/44 , C07C237/20 , C07D309/06 , C07D309/04 , C07C235/36 , C07D317/46 , C07D277/30 , A61K31/426 , A61K39/39 , A61P35/00 , A61P37/06 , A61K31/277 , A61K31/343 , A61K31/44 , A61K31/505 , A61K31/5375 , C07C233/11 , C07C233/28 , C07C323/41 , C07D317/66
摘要： Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
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公开(公告)号：US20190092729A1
公开(公告)日：2019-03-28
申请号：US15524113
申请日：2015-11-05
发明人： Hilary Plake BECK , Juan Carlos JAEN , Maksim OSIPOV , Jay Patrick POWERS , Maureen Kay REILLY , Hunter Paul SHUNATONA , James Ross WALKER , Mikhail ZIBINSKY , James Aaron BALOG , David K. WILLIAMS , Weiwei GUO
IPC分类号： C07D213/75 , A61K31/44 , C07D239/42 , A61K31/505 , C07C233/28 , A61K31/167 , C07C233/15 , C07C233/11 , C07C255/60 , A61K31/277 , C07D317/66 , A61K31/343 , C07C323/41 , C07C317/40 , A61K45/06 , C07D295/155 , A61K31/5375 , A61P37/06
摘要： Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
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公开(公告)号：US20180282281A1
公开(公告)日：2018-10-04
申请号：US15524396
申请日：2015-11-05
发明人： Hilary Plake BECK , Juan Carios JAEN , Maksim OSIPOV , Jay Patrick POWERS , Maureen Kay REILLY , Hunter Paul SHUNATONA , James Ross WALKER , Mikhail ZIBINSKY , James Aaron BALOG , David K. WILLIAMS , Jay A. MARKWALDER , Emily Charlotte CHERNEY , Welfang SHAN , Audris HUANG
IPC分类号： C07D215/12 , C07D215/233 , C07D217/12 , C07D217/24 , C07D231/56 , C07D239/74 , C07D401/12 , C07D471/04 , C07D487/04 , A61P35/02
摘要： Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
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公开(公告)号：US20180325889A1
公开(公告)日：2018-11-15
申请号：US15524092
申请日：2015-11-05
发明人： Hilary Plake BECK , Juan Carlos JAEN , Maksim OSIPOV , Jay Patrick POWERS , Maureen Kay REILLY , Hunter Paul SHUNATONA , James Ross WALKER , Mikhail ZIBINSKY , James Aaron BALOG , David K. Williams , Jay A. MARKWALDER , Steven P. SEITZ , Emily Charlotte CHERNEY , Liping ZHANG , Weifang SHAN , Weiwei GUO , Audris HUANG
IPC分类号： A61K31/47 , A61P35/00 , A61K31/381
CPC分类号： A61K31/47 , A61K31/00 , A61K31/136 , A61K31/166 , A61K31/277 , A61K31/381 , A61K31/4412 , A61K31/445 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K45/06 , A61K2300/00 , A61P35/00 , C07C211/45 , C07C217/80 , C07C233/10 , C07C233/59 , C07C233/60 , C07C233/65 , C07C233/74 , C07C255/50 , C07C255/58 , C07C275/30 , C07C2601/14 , C07D211/08 , C07D213/68 , C07D215/04 , C07D215/233 , C07D487/04 , C07K16/18
摘要： Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
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