公开(公告)号：US20190219492A1

公开(公告)日：2019-07-18

申请号：US16364186

申请日：2019-03-26

Applicant: FUJIFILM CORPORATION

Inventor： Xiao LING ,  Kiyokazu HASHIMOTO ,  Haruki TOMIKAWA

IPC: G01N15/04 ,  G01N27/72

CPC classification number: G01N15/04 ,  G01N27/72 ,  G01N33/5005 ,  G01N2015/0042

Abstract: Provided is a medium evaluation method for evaluating the suitability of a medium in which cell aggregates are cultured in a suspended state, by which an evaluation of whether a medium is adequate for both the cell retention performance and the cell recovery efficiency, the medium evaluation method including dispersing a plurality of particles in a medium, measuring a sedimentation velocity by which the particles settle in the medium, and using the sedimentation velocity thus measured as an index value indicating the suitability of the medium; and also provided are a medium and a culture method.

公开(公告)号：US20210379098A1

公开(公告)日：2021-12-09

申请号：US17407132

申请日：2021-08-19

Applicant: FUJIFILM Corporation

Inventor： Kosuke CHIBA ,  Koji TAKAKU ,  Haruki TOMIKAWA

IPC: A61K31/765 ,  A61K31/14 ,  A61K31/231 ,  A61K31/685

Abstract: A biomaterial includes a neutral acyl lipid and an amphipathic block copolymer which contains a hydrophilic segment and a hydrophobic segment and in which a difference in ClogP value between the hydrophilic segment and the hydrophobic segment is more than 1.00, and in the biomaterial, a content of the amphipathic block copolymer is 1.0% to 20% by mass with respect to a total mass of a solid content of the biomaterial.

公开(公告)号：US20240415799A1

公开(公告)日：2024-12-19

申请号：US18815847

申请日：2024-08-27

Applicant: FUJIFILM Corporation

Inventor： Haruki TOMIKAWA ,  Toshihide YOSHITANI

IPC: A61K31/231 ,  A61K31/045 ,  A61K31/685 ,  A61K45/06

Abstract: In the present invention, there is provided a composition for a living body, which has excellent spreadability on an object, has a high film formation rate in a case of being brought into contact with water to form a film, and has excellent strength and excellent controlled release characteristics of the film. The present invention relates to a composition for a living body, containing a neutral acyl lipid, a phospholipid, an alcohol having 4 or less carbon atoms or a polyalkylene oxide, and a physiologically active substance, in which a content of a neutral diacyl lipid in the neutral acyl lipid is more than 0% by mass and 50% by mass or less, and a mass ratio of a content of the neutral acyl lipid to a content of the phospholipid is 54/46 to 1/99.

公开(公告)号：US20230050406A1

公开(公告)日：2023-02-16

申请号：US17815933

申请日：2022-07-28

Applicant: FUJIFILM CORPORATION

Inventor： Haruki TOMIKAWA ,  Toshihide YOSHITANI ,  Kyohisa UCHIUMI ,  Ren ISHIKAWA

IPC: C09J7/29 ,  B32B5/02 ,  B32B27/36 ,  B32B27/12 ,  B32B7/12

Abstract: Provided is a film and a water stopping tape that realize long-lasting water stopping properties. The film includes an outermost layer containing a water-absorbent polymer having a water absorbency of 5 g/g to 100 g/g that is represented by a ratio of a mass of a sample having been immersed in water for 3 hours to a mass of the sample not yet being immersed in water a permeable layer, and a substrate layer in this order, and the water stopping tape includes the film.

公开(公告)号：US20230039137A1

公开(公告)日：2023-02-09

申请号：US17815934

申请日：2022-07-28

Applicant: FUJIFILM CORPORATION

Inventor： Haruki TOMIKAWA ,  Toshihide YOSHITANI ,  Kyohisa UCHIUMI ,  Ren ISHIKAWA

IPC: B01J20/26 ,  B01J20/28 ,  B32B27/12

Abstract: Provided are a film and a water stopping tape that realize long-lasting water stopping properties. The film includes an outermost layer that contains a water-absorbent polymer and a fiber assembly and a substrate layer in this order, in which a degree of out-of-plane swelling of the outermost layer is higher than a degree of in-plane swelling of the outermost layer, and the water stopping tape includes the film.

公开(公告)号：US20210177736A1

公开(公告)日：2021-06-17

申请号：US17186229

申请日：2021-02-26

Applicant: FUJIFILM Corporation

Inventor： Haruki TOMIKAWA ,  Koji TAKAKU ,  Kosuke CHIBA ,  Takafumi HOSOKAWA

IPC: A61K9/00 ,  A61K9/51 ,  A61K47/26 ,  A61K47/24 ,  A61K47/32

Abstract: Provided is a biocompatible material capable of forming a gel having excellent retention and scratch resistance. The biocompatible material according to the embodiment of the present invention includes an alginate having a weight-average molecular weight of 1 million or more, an aluminum compound, a carboxyvinyl polymer, and an oil-based base material. However, the biocompatible material is substantially free of water.

公开(公告)号：US20240423943A1

公开(公告)日：2024-12-26

申请号：US18827826

申请日：2024-09-08

Applicant: FUJIFILM Corporation

Inventor： Haruki TOMIKAWA ,  Toshihide YOSHITANI

IPC: A61K31/231 ,  A61K9/06 ,  A61K31/047 ,  A61K31/685

Abstract: In the present invention, there is provided a composition for a living body, which has excellent spreadability on an object, has a high film formation rate in a case of being brought into contact with water to form a film, increases the moisture retention of an object adjacent to the formed film, and has excellent strength of the formed film. The present invention relates to a composition for a living body, containing a neutral acyl lipid, a phospholipid, and an alcohol having 4 or less carbon atoms or a polyalkylene oxide, in which a content of a neutral diacyl lipid in the neutral acyl lipid is more than 0% by mass and 50% by mass or less, and a mass ratio of a content of the neutral acyl lipid to a content of the phospholipid is 54/46 to 30/70.

公开(公告)号：US20220365056A1

公开(公告)日：2022-11-17

申请号：US17865877

申请日：2022-07-15

Applicant: FUJIFILM Corporation

Inventor： Haruki TOMIKAWA ,  Toshihide YOSHITANI

IPC: G01N33/15

Abstract: The present invention provides a biological mucous membrane model having high reproducibility of the evaluation result of the retention that is obtained in a case where a mucous membrane protective agent is applied to the mucous membrane of the living body, in a case where the mucous membrane protective agent such as an oral mucous membrane protective agent is applied; and a method of evaluating retention of a mucous membrane protective agent. The biological mucous membrane model according to the embodiment of the present invention has a hydrogel layer, a lipid-containing layer containing a lipid, which is disposed on the hydrogel layer and has through-holes along in a thickness direction, and a hydrophilic polymer layer disposed on the lipid-containing layer in this order.