-
公开(公告)号：US07605164B2
公开(公告)日：2009-10-20
申请号：US11353252
申请日：2006-02-14
申请人： Fady Malik , Adam Lewis Tomasi , Bainian Feng , Erica Anne Kraynack , Kathleen A. Elias , Pu-Ping Lu , Whitney Walter Smith , Xiangping Qian , David J. Morgans, Jr.
发明人： Fady Malik , Adam Lewis Tomasi , Bainian Feng , Erica Anne Kraynack , Kathleen A. Elias , Pu-Ping Lu , Whitney Walter Smith , Xiangping Qian , David J. Morgans, Jr.
IPC分类号： A61K31/497 , A61K31/381 , A61K31/4409 , A61K31/4406 , A61K31/4402 , A61K31/42 , A61P9/04 , C07D401/10 , C07D403/10 , C07D213/643 , C07D213/65 , C07D213/68 , C07D261/18 , C07D333/22
CPC分类号： C07D401/12 , A61K31/4412 , A61K31/444 , A61K31/513 , C07D213/65 , C07D261/18 , C07D333/38 , C07D409/12 , C07D413/12
摘要： Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的苯甲酰胺衍生物选择性地调节心脏肌节，例如通过增强心肌肌球蛋白，并且可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
-
公开(公告)号：US06908923B2
公开(公告)日：2005-06-21
申请号：US10327219
申请日：2002-12-20
申请人： Fady Malik , Adam Lewis Tomasi , Bainian Feng , Erica Anne Kraynack , Kathleen A. Elias , Pu-Ping Lu , Whitney Walter Smith , Xiangping Qian , David J. Morgans, Jr.
发明人： Fady Malik , Adam Lewis Tomasi , Bainian Feng , Erica Anne Kraynack , Kathleen A. Elias , Pu-Ping Lu , Whitney Walter Smith , Xiangping Qian , David J. Morgans, Jr.
IPC分类号： C07D333/40 , A61K31/381 , A61K31/42 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/455 , A61K31/497 , A61P9/00 , A61P9/04 , C07D213/64 , C07D213/65 , C07D213/75 , C07D213/78 , C07D213/81 , C07D261/18 , C07D333/38 , C07D401/04 , C07D401/12 , C07D401/14 , C07D409/12 , C07D413/12 , A61K31/4965 , A01N43/40 , A01N43/80 , A61K31/44
CPC分类号： C07D401/12 , A61K31/4412 , A61K31/444 , A61K31/513 , C07D213/65 , C07D261/18 , C07D333/38 , C07D409/12 , C07D413/12
摘要： Certain substituted benzamide derivatives of Formula I: selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的式I的苯甲酰胺衍生物：选择性调节心肌肉瘤，例如通过增强心肌肌球蛋白，并且可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
-
公开(公告)号：US07053094B2
公开(公告)日：2006-05-30
申请号：US11040478
申请日：2005-01-20
申请人： Fady Malik , Adam Lewis Tomasi , Bainian Feng , Erica Anne Kraynack , Kathleen A. Elias , Pu-Ping Lu , Whitney Walter Smith , Xiangping Qian , David J. Morgans, Jr.
发明人： Fady Malik , Adam Lewis Tomasi , Bainian Feng , Erica Anne Kraynack , Kathleen A. Elias , Pu-Ping Lu , Whitney Walter Smith , Xiangping Qian , David J. Morgans, Jr.
IPC分类号： A61K31/4965 , A61K31/44 , A61K31/42 , A01N43/40 , A01N43/80
CPC分类号： C07D401/12 , A61K31/4412 , A61K31/444 , A61K31/513 , C07D213/65 , C07D261/18 , C07D333/38 , C07D409/12 , C07D413/12
摘要： Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
-
公开(公告)号：US07399866B2
公开(公告)日：2008-07-15
申请号：US10541596
申请日：2004-01-14
申请人： Bradley Paul Morgan , Kathleen A. Elias , Erica Anne Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Walter Smith , Todd Tochimoto , Adam Lewis Tomasi , David J. Morgans, Jr.
发明人： Bradley Paul Morgan , Kathleen A. Elias , Erica Anne Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Walter Smith , Todd Tochimoto , Adam Lewis Tomasi , David J. Morgans, Jr.
IPC分类号： C07D211/68 , C07D401/04 , C07D401/14
CPC分类号： A61K31/44 , A61K31/17 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/40 , C07D207/12 , C07D211/42 , C07D213/65 , C07D213/70 , C07D213/75 , C07D217/04 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D498/04 , C07D513/04
摘要： Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的脲衍生物选择性调节心脏肌节，例如通过增强心肌肌球蛋白，可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
-
公开(公告)号：US20090176307A1
公开(公告)日：2009-07-09
申请号：US12348786
申请日：2009-01-05
申请人： Bradley Paul Morgan , Kathleen A. Elias , Erica Anne Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Walter Smith , Todd Tochimoto , Adam Lewis Tomasi , David J. Morgans, JR.
发明人： Bradley Paul Morgan , Kathleen A. Elias , Erica Anne Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Walter Smith , Todd Tochimoto , Adam Lewis Tomasi , David J. Morgans, JR.
IPC分类号： C12N5/08
CPC分类号： A61K31/44 , A61K31/17 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/40 , C07D207/12 , C07D211/42 , C07D213/65 , C07D213/70 , C07D213/75 , C07D217/04 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D498/04 , C07D513/04
摘要： Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
-
公开(公告)号：US07491826B2
公开(公告)日：2009-02-17
申请号：US10890829
申请日：2004-07-14
申请人： Bradley Paul Morgan , Kathleen A. Elias , Erica Anne Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Walter Smith , Todd Tochimoto , Adam Lewis Tomasi , David J. Morgans, Jr.
发明人： Bradley Paul Morgan , Kathleen A. Elias , Erica Anne Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Walter Smith , Todd Tochimoto , Adam Lewis Tomasi , David J. Morgans, Jr.
IPC分类号： C07D211/68 , C07D401/04 , C07D401/14
CPC分类号： A61K31/44 , A61K31/17 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/40 , C07D207/12 , C07D211/42 , C07D213/65 , C07D213/70 , C07D213/75 , C07D217/04 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D498/04 , C07D513/04
摘要： Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的脲衍生物选择性地调节心肌肉瘤，例如通过增强心肌肌球蛋白，并且可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
-
公开(公告)号：US20060173024A1
公开(公告)日：2006-08-03
申请号：US11353252
申请日：2006-02-14
申请人： Fady Malik , Adam Tomasi , Bainian Feng , Erica Kraynack , Kathleen Elias , Pu-Ping Lu , Whitney Smith , Xiangping Qian , David Morgans
发明人： Fady Malik , Adam Tomasi , Bainian Feng , Erica Kraynack , Kathleen Elias , Pu-Ping Lu , Whitney Smith , Xiangping Qian , David Morgans
IPC分类号： A61K31/513 , A61K31/444 , A61K31/4412 , C07D401/02
CPC分类号： C07D401/12 , A61K31/4412 , A61K31/444 , A61K31/513 , C07D213/65 , C07D261/18 , C07D333/38 , C07D409/12 , C07D413/12
摘要： Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
-
公开(公告)号：US20050148638A1
公开(公告)日：2005-07-07
申请号：US11040478
申请日：2005-01-20
申请人： Fady Malik , Adam Tomasi , Bainian Feng , Erica Kraynack , Kathleen Elias , Pu-Ping Lu , Whitney Smith , Xiangping Qian , David Morgans
发明人： Fady Malik , Adam Tomasi , Bainian Feng , Erica Kraynack , Kathleen Elias , Pu-Ping Lu , Whitney Smith , Xiangping Qian , David Morgans
IPC分类号： C07D333/40 , A61K31/381 , A61K31/42 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/455 , A61K31/497 , A61P9/00 , A61P9/04 , C07D213/64 , C07D213/65 , C07D213/75 , C07D213/78 , C07D213/81 , C07D261/18 , C07D333/38 , C07D401/04 , C07D401/12 , C07D401/14 , C07D409/12 , C07D413/12 , A61K31/44 , A61K31/16 , A61K31/165 , A61K31/277
CPC分类号： C07D401/12 , A61K31/4412 , A61K31/444 , A61K31/513 , C07D213/65 , C07D261/18 , C07D333/38 , C07D409/12 , C07D413/12
摘要： Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的苯甲酰胺衍生物选择性地调节心脏肌节，例如通过增强心肌肌球蛋白，并且可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
-
公开(公告)号：US20120172372A1
公开(公告)日：2012-07-05
申请号：US13341413
申请日：2011-12-30
申请人： Bradley Paul Morgan , Alex Muci , Pu-Ping Lu , Erica Anne Kraynack , Todd Tochimoto , David J. Morgans, JR.
发明人： Bradley Paul Morgan , Alex Muci , Pu-Ping Lu , Erica Anne Kraynack , Todd Tochimoto , David J. Morgans, JR.
IPC分类号： A61K31/496 , A61P9/04 , A61K31/5377 , C07D401/12 , C07D413/12
CPC分类号： C07D213/75 , C07D211/56 , C07D239/42 , C07D261/14 , C07D263/48 , C07D271/113 , C07D295/26 , C07D401/10 , C07D401/12 , C07D417/00 , C07D417/10 , C07D417/12 , C07D487/04 , C07D491/04 , C07D513/04
摘要： Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的脲衍生物选择性地调节心肌肉瘤，例如通过增强心肌肌球蛋白，并且可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
-
公开(公告)号：US08110595B2
公开(公告)日：2012-02-07
申请号：US11630062
申请日：2005-06-16
申请人： Bradley Paul Morgan , Alex Muci , Pu-Ping Lu , Erica Anne Kraynack , Todd Tochimoto , David J. Morgans, Jr.
发明人： Bradley Paul Morgan , Alex Muci , Pu-Ping Lu , Erica Anne Kraynack , Todd Tochimoto , David J. Morgans, Jr.
IPC分类号： A61K31/40 , C07D261/02 , C07D295/04
CPC分类号： C07D213/75 , C07D211/56 , C07D239/42 , C07D261/14 , C07D263/48 , C07D271/113 , C07D295/26 , C07D401/10 , C07D401/12 , C07D417/00 , C07D417/10 , C07D417/12 , C07D487/04 , C07D491/04 , C07D513/04
摘要： Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的脲衍生物选择性地调节心肌肉瘤，例如通过增强心肌肌球蛋白，并且可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
-
-
-
-
-
-
-
-
-
搜索结果
77 条记录 (耗时 0.05 秒)
