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1.发明公开公开(公告)号：US20240058215A1
公开(公告)日：2024-02-22
申请号：US18257065
申请日：2021-12-17
申请人： Fenwal, Inc.
CPC分类号： A61J1/10 , A61J1/1468 , A61M1/0218 , A61M2202/0429
摘要： Medical containers and disposable fluid circuits (kits) including such containers are disclosed. The containers and kit components are made of a plastic composition including polyvinyl chloride and one or more plasticizers such as a citrate ester and an epoxidized vegetable oil are disclosed. Containers made from such compositions are useful in the storage red blood cells. Red blood cell products wherein the red blood cells exhibit a reduced level of hemolysis are also disclosed.
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公开(公告)号：US10967389B2
公开(公告)日：2021-04-06
申请号：US15358200
申请日：2016-11-22
申请人： Fenwal, Inc.
发明人： Richard L. West , Daniel R. Lynn
摘要： A centrifuge rotor assembly includes a chamber assembly, a bearing support, and a counterweight that is substantially diametrically opposed to the bearing support with respect to the chamber assembly. The chamber assembly receives a processing chamber of a fluid circuit, while the bearing support receives a portion of an umbilicus that is fluidly connected to the processing chamber. The bearing support and counterweight are rotated about a central axis of the chamber assembly by an electric drive of the centrifuge rotor assembly, with the bearing support and counterweight remaining substantially diametrically opposed to each other with respect to the chamber assembly while being rotated about the central axis. The electric drive may rotate the bearing support and counterweight at a plurality of different speeds, with the counterweight automatically moving with respect to the bearing support between radially innermost and radially outermost positions to balance the centrifuge rotor assembly.
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公开(公告)号：US10376620B2
公开(公告)日：2019-08-13
申请号：US14677319
申请日：2015-04-02
申请人： Fenwal, Inc.
发明人： Daniel R. Lynn , Daryl R. Calhoun
摘要： Systems and methods are provided for separating a red blood cell-containing fluid into separated red blood cells and another fluid constituent. A suitable system includes a disposable fluid flow circuit and a durable, reusable separation system, with the circuit being mounted onto or otherwise associated with the separation system. The circuit includes a membrane separator for separating the fluid into its constituent parts, as well as a leukoreduction filter. The leukoreduction filter may be used before or after the red blood cell-containing fluid has been passed into the membrane separator. The red blood cell-containing fluid (if the leukoreduction filter is positioned upstream of the membrane separator) or the separated red blood cells (if the leukoreduction filter is positioned downstream of the membrane separator) may also be passed through a microaggregate filter prior to passing through the leukoreduction filter.
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公开(公告)号：US08870828B2
公开(公告)日：2014-10-28
申请号：US13693189
申请日：2012-12-04
申请人： Fenwal, Inc.
CPC分类号： A61B5/150541 , A61B5/1405 , A61B5/15003 , A61B5/150259 , A61B5/150366 , A61B5/150389 , A61B5/150519 , A61B5/150549 , A61B5/150587 , A61B5/150595 , A61B5/150618 , A61B5/150717 , A61B5/153 , A61M5/3202 , A61M2005/312
摘要： Medical needle assemblies incorporating a needle cover are provided. According to one aspect, the needle cover is integrally formed from a material that: (1) is sufficiently rigid to prevent bending of an underlying cannula, (2) is suitable for allowing a frangible portion thereof to be broken under pre-selected conditions, and/or (3) has a moisture vapor transmission rate sufficient for steam sterilization of a needle tip enclosed by the needle cover. According to another aspect, at least part of a cap portion and a hub portion of the needle cover are translucent. According to yet another aspect, the needle cover is provided with a wing having an enlarged rib suitable for gripping during separation of a cap portion from the remainder of the needle cover.
摘要翻译： 提供了包括针盖的医用针组件。 根据一个方面，针盖由以下材料整体形成：（1）足够刚性以防止下面的套管弯曲，（2）适合于允许其易碎部分在预先选定的条件下破裂， 和/或（3）具有足够用于由针盖包围的针尖的蒸汽灭菌的水蒸汽透过率。 根据另一方面，针罩的帽部和轮毂部的至少一部分是半透明的。 根据另一方面，针盖设置有翼，其具有适于在帽部分与针盖的其余部分分离期间抓握的扩大的肋。
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公开(公告)号：US20130096462A1
公开(公告)日：2013-04-18
申请号：US13693189
申请日：2012-12-04
申请人： Fenwal, Inc.
IPC分类号： A61B5/15
CPC分类号： A61B5/150541 , A61B5/1405 , A61B5/15003 , A61B5/150259 , A61B5/150366 , A61B5/150389 , A61B5/150519 , A61B5/150549 , A61B5/150587 , A61B5/150595 , A61B5/150618 , A61B5/150717 , A61B5/153 , A61M5/3202 , A61M2005/312
摘要： Medical needle assemblies incorporating a needle cover are provided. According to one aspect, the needle cover is integrally formed from a material that: (1) is sufficiently rigid to prevent bending of an underlying cannula, (2) is suitable for allowing a frangible portion thereof to be broken under pre-selected conditions, and/or (3) has a moisture vapor transmission rate sufficient for steam sterilization of a needle tip enclosed by the needle cover. According to another aspect, at least part of a cap portion and a hub portion of the needle cover are translucent. According to yet another aspect, the needle cover is provided with a wing having an enlarged rib suitable for gripping during separation of a cap portion from the remainder of the needle cover.
摘要翻译： 提供了包括针盖的医用针组件。 根据一个方面，针盖由以下材料整体形成：（1）足够刚性以防止下面的套管弯曲，（2）适合于允许其易碎部分在预先选定的条件下被破坏， 和/或（3）具有足够用于由针盖包围的针尖的蒸汽灭菌的水蒸汽透过率。 根据另一方面，针罩的帽部和轮毂部的至少一部分是半透明的。 根据另一方面，针盖设置有翼，其具有适于在帽部分与针盖的其余部分分离期间抓握的扩大的肋。
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公开(公告)号：US11097037B2
公开(公告)日：2021-08-24
申请号：US16439887
申请日：2019-06-13
申请人： Fenwal, Inc.
发明人： Daniel R. Lynn , Daryl R. Calhoun
摘要： Systems and methods are provided for separating a red blood cell-containing fluid into separated red blood cells and another fluid constituent. A suitable system includes a disposable fluid flow circuit and a durable, reusable separation system, with the circuit being mounted onto or otherwise associated with the separation system. The circuit includes a membrane separator for separating the fluid into its constituent parts, as well as a leukoreduction filter. The leukoreduction filter may be used before or after the red blood cell-containing fluid has been passed into the membrane separator. The red blood cell-containing fluid (if the leukoreduction filter is positioned upstream of the membrane separator) or the separated red blood cells (if the leukoreduction filter is positioned downstream of the membrane separator) may also be passed through a microaggregate filter prior to passing through the leukoreduction filter.
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公开(公告)号：US20170144172A1
公开(公告)日：2017-05-25
申请号：US15358200
申请日：2016-11-22
申请人： Fenwal, Inc.
发明人： Richard L. West , Daniel R. Lynn
CPC分类号： B04B9/14 , A61M1/3693 , B04B5/0442 , B04B9/12 , B04B2005/0492
摘要： A centrifuge rotor assembly includes a chamber assembly, a bearing support, and a counterweight that is substantially diametrically opposed to the bearing support with respect to the chamber assembly. The chamber assembly receives a processing chamber of a fluid circuit, while the bearing support receives a portion of an umbilicus that is fluidly connected to the processing chamber. The bearing support and counterweight are rotated about a central axis of the chamber assembly by an electric drive of the centrifuge rotor assembly, with the bearing support and counterweight remaining substantially diametrically opposed to each other with respect to the chamber assembly while being rotated about the central axis. The electric drive may rotate the bearing support and counterweight at a plurality of different speeds, with the counterweight automatically moving with respect to the bearing support between radially innermost and radially outermost positions to balance the centrifuge rotor assembly.
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8.发明申请Systems And Methods For Leukoreducing A Red Blood Cell-Containing Fluid And Concentrated Red Blood Cells 审中-公开用于白血病诱导的含有红细胞的液体和浓缩红细胞的系统和方法公开(公告)号：US20160289638A1
公开(公告)日：2016-10-06
申请号：US14677319
申请日：2015-04-02
申请人： Fenwal, Inc.
发明人： Daniel R. Lynn , Daryl R. Calhoun
IPC分类号： C12N5/078
CPC分类号： C12N5/0641 , A61M1/0218 , A61M1/0272 , A61M1/265 , A61M1/3633 , A61M2202/0429
摘要： Systems and methods are provided for separating a red blood cell-containing fluid into separated red blood cells and another fluid constituent. A suitable system includes a disposable fluid flow circuit and a durable, reusable separation system, with the circuit being mounted onto or otherwise associated with the separation system. The circuit includes a membrane separator for separating the fluid into its constituent parts, as well as a leukoreduction filter. The leukoreduction filter may be used before or after the red blood cell-containing fluid has been passed into the membrane separator. The red blood cell-containing fluid (if the leukoreduction filter is positioned upstream of the membrane separator) or the separated red blood cells (if the leukoreduction filter is positioned downstream of the membrane separator) may also be passed through a microaggregate filter prior to passing through the leukoreduction filter.
摘要翻译： 提供了用于将含红细胞的流体分离成分离的红细胞和另一种流体成分的系统和方法。 合适的系统包括一次性流体流动回路和耐用的可重复使用的分离系统，其中电路安装在分离系统上或以其它方式与分离系统相关联。 电路包括用于将流体分离成其组成部分的膜分离器，以及白细胞减压过滤器。 白细胞减退过滤器可以在含有红细胞的流体进入膜分离器之前或之后使用。 含红细胞的流体（如果白细胞减少过滤器位于膜分离器的上游）或分离的红细胞（如果白细胞减少过滤器位于膜分离器的下游）也可以在通过之前通过微聚集过滤器 通过白细胞减少过滤器。
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