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公开(公告)号：US12076731B2
公开(公告)日：2024-09-03
申请号：US17336394
申请日：2021-06-02
Applicant: Fenwal, Inc.
Inventor： Gregory G. Pieper , Salvatore Manzella, Jr. , Brian C. Case , Steven R Katz , Kyungyoon Min
CPC classification number: B04B7/08 , B04B5/0442 , B04B2005/045
Abstract: Fluid separation chambers are provided for rotation about an axis in a fluid processing system. The fluid separation chamber may be provided with first and second stages, with the first and second stages being positioned at different axial locations. In another embodiment, at least one of the stages may be provided with a non-uniform outer diameter about the rotational axis, which may define a generally spiral-shaped profile or a different profile for fractionating a fluid or fluid component. One or more of the stages may also have a varying outer diameter along the axis. The profile of the chamber may be provided by the chamber itself (in the case of rigid chambers) or by an associated fixture or centrifuge apparatus (in the case of flexible chambers).
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公开(公告)号：US11052408B2
公开(公告)日：2021-07-06
申请号：US16790815
申请日：2020-02-14
Applicant: Fenwal, Inc.
Inventor： Gregory G. Pieper , Salvatore Manzella, Jr. , Brian C. Case , Steven R. Katz , Kyungyoon Min
Abstract: Fluid separation chambers are provided for rotation about an axis in a fluid processing system. The fluid separation chamber may be provided with first and second stages, with the first and second stages being positioned at different axial locations. In another embodiment, at least one of the stages may be provided with a non-uniform outer diameter about the rotational axis, which may define a generally spiral-shaped profile or a different profile for fractionating a fluid or fluid component. One or more of the stages may also have a varying outer diameter along the axis. The profile of the chamber may be provided by the chamber itself (in the case of rigid chambers) or by an associated fixture or centrifuge apparatus (in the case of flexible chambers).
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公开(公告)号：US09968946B2
公开(公告)日：2018-05-15
申请号：US15062323
申请日：2016-03-07
Applicant: Fenwal, Inc.
Inventor： Gregory G. Pieper , Salvatore Manzella, Jr. , Brian C. Case , Steven R. Katz , Kyungyoon Min
CPC classification number: B04B7/08 , B04B5/0442 , B04B2005/045
Abstract: Centrifuges are provided for rotating fluid separation chambers about an axis in a fluid processing system. The centrifuge may be provided with high- and low-G walls, with a gap defined between the high- and low-G walls. A first section of the gap may have a substantially uniform radius about the axis, while a second section of the gap may have a non-uniform radius about the axis. The radius of the second section of the gap about the axis at all locations is no larger than the radius of the first section of the gap about the axis. The high-G wall may comprise an inner surface of an outer bowl, while the low-G wall may comprise an outer surface of an inner spool. At least a portion of the second section of the gap may have a varying radius along the axis and/or be configured as a spiral.
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公开(公告)号：US09816073B2
公开(公告)日：2017-11-14
申请号：US14810058
申请日：2015-07-27
Applicant: Fenwal, Inc.
CPC classification number: C12N5/0641 , A61L2/0047 , A61L2202/14 , A61L2202/22 , A61M1/0209 , A61M1/3681 , A61M1/3683 , A61M1/3696 , A61M2205/051 , A61M2205/12 , A61M2205/15 , A61M2205/3306 , C12M37/00 , C12M41/48
Abstract: An irradiation device includes a fluid treatment chamber configured to receive a biological fluid container, the fluid treatment chamber having opposing first and second sides, at least one light source disposed adjacent at least one of the first and second sides of the fluid treatment chamber, and an overflow reservoir in fluid communication with the fluid treatment chamber to receive fluid leaking from the biological fluid container. The device also includes a non-contact sensor disposed adjacent the overflow reservoir and configured to generate a signal according to leaked fluid in the overflow reservoir, an indicator, and a controller coupled to the at least one light source, the non-contact sensor and the indicator, the controller configured to activate the indicator upon receipt of the signal from the sensor and to deactivate the at least one light source subsequent to receipt of the signal from the sensor.
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公开(公告)号：US09101944B2
公开(公告)日：2015-08-11
申请号：US14113231
申请日：2012-11-15
Applicant: FENWAL INC.
Inventor： Salvatore J. Manzella , Gregory G. Pieper , Thimothy J. Getschman
CPC classification number: B04B9/08 , B04B5/0442
Abstract: A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular velocity and rotating the chamber assembly (30 coaxially with the yoke assembly at a second angular velocity A drive motor (54) is provided for rotating the yoke assembly at the first angular velocity and simultaneously rotating the chamber assembly at the second angular velocity by means of a stationary first gear (64), a second gear (68) mounted to the yoke assembly that operatively engages the first gear, a third gear (74) rotatably mounted to the yoke assembly so as to synchronously rotate with the second gear, and a fourth gear (76) fixed to the chamber assembly that operatively engages the third gear so as to rotate the chamber assembly (30) relative to the yoke assembly (36) upon rotation of the yoke assembly about the first gear.
Abstract translation: 提供了一种用于离心处理系统的驱动组件，用于以第一角速度绕第一轴线旋转轭组件（36），并以第二角速度A驱动马达（54）与腔组件（30与轴组件同轴地旋转） 提供用于以第一角速度旋转轭组件，并且借助于固定的第一齿轮（64）以第二角速度同时旋转腔室组件;安装到轭组件的第二齿轮（68），其可操作地接合第一 齿轮，可旋转地安装到轭组件以与第二齿轮同步旋转的第三齿轮（74）和固定到腔室组件的第四齿轮（76），其可操作地接合第三齿轮以旋转腔室组件 当轭组件围绕第一齿轮旋转时相对于轭组件（36）。
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Patent Agency Ranking
公开(公告)号：US20210291200A1
公开(公告)日：2021-09-23
申请号：US17336394
申请日：2021-06-02
Applicant: Fenwal, Inc.
Inventor： Gregory G. Pieper , Salvatore Manzella, JR. , Brian C. Case , Steven R. Katz , Kyungyoon Min
Abstract: Fluid separation chambers are provided for rotation about an axis in a fluid processing system. The fluid separation chamber may be provided with first and second stages, with the first and second stages being positioned at different axial locations. In another embodiment, at least one of the stages may be provided with a non-uniform outer diameter about the rotational axis, which may define a generally spiral-shaped profile or a different profile for fractionating a fluid or fluid component. One or more of the stages may also have a varying outer diameter along the axis. The profile of the chamber may be provided by the chamber itself (in the case of rigid chambers) or by an associated fixture or centrifuge apparatus (in the case of flexible chambers).
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公开(公告)号：US20180221891A1
公开(公告)日：2018-08-09
申请号：US15943877
申请日：2018-04-03
Applicant: Fenwal, Inc.
Inventor： Gregory G. Pieper , Salvatore Manzella, JR. , Brian C. Case , Steven R. Katz , Kyungyoon Min
CPC classification number: B04B7/08 , B04B5/0442 , B04B2005/045
Abstract: Fluid separation chambers are provided for rotation about an axis in a fluid processing system. The fluid separation chamber may be provided with first and second stages, with the first and second stages being positioned at different axial locations. In another embodiment, at least one of the stages may be provided with a non-uniform outer diameter about the rotational axis, which may define a generally spiral-shaped profile or a different profile for fractionating a fluid or fluid component. One or more of the stages may also have a varying outer diameter along the axis. The profile of the chamber may be provided by the chamber itself (in the case of rigid chambers) or by an associated fixture or centrifuge apparatus (in the case of flexible chambers).
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公开(公告)号：US09545637B2
公开(公告)日：2017-01-17
申请号：US14693518
申请日：2015-04-22
Applicant: Fenwal, Inc.
Inventor： Salvatore Manzella , Gregory G. Pieper
CPC classification number: B04B9/12 , A61M1/3693 , A61M1/3696 , B04B5/0442 , B04B2005/0492 , F16C11/06 , F16C17/12 , F16C2316/10
Abstract: A fluid circuit for use with a fluid processing assembly, the fluid circuit comprising an umbilicus having a first end, a second end, an axis of rotation, and a cross-sectional circumference; a one-piece bearing secured to the umbilicus at a location between the first and second ends, the bearing having an axis of rotation and including an inner lumen which directly engages the umbilicus and includes a plurality of traction features, which bear against the umbilicus to prevent relative rotation of the bearing and the umbilicus; and the plurality of traction features comprising a first traction feature configured to engage the umbilicus at a first length between the first and second ends and a second traction feature configured to engage the umbilicus at a second length between the first and second ends.
Abstract translation: 一种与流体处理组件一起使用的流体回路，所述流体回路包括具有第一端，第二端，旋转轴线和横截面圆周的脐带; 在第一和第二端之间的位置处固定到脐部的单件式轴承，所述轴承具有旋转轴线，并且包括直接接合脐部的内腔，并且包括多个牵引特征，所述牵引特征承载于所述脐部至 防止轴承和脐带相对旋转; 并且所述多个牵引特征包括构造成在所述第一和第二端之间以第一长度接合所述脐部的第一牵引特征，以及构造成在所述第一和第二端之间以第二长度接合所述脐带的第二牵引特征。
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公开(公告)号：US20140274648A1
公开(公告)日：2014-09-18
申请号：US13835255
申请日：2013-03-15
Applicant: FENWAL, INC.
Inventor： Gregory G. Pieper , Salvatore Manzella, JR. , Terry Chung , Brian Case , Richard West
IPC: B04B5/04
CPC classification number: B04B5/0442 , B04B2005/0492 , Y10T29/494
Abstract: An umbilicus for use in an umbilicus-drive fluid processing centrifuge system is disclosed, together with a method of making it and a fluid flow circuit including such umbilicus. The umbilicus includes an elongated umbilicus body, a first end fitting defining an interior cavity, an adapter received within the interior cavity and having at least one port extension extending into a fluid transmitting lumen of the umbilicus body, the adapter and end fitting including interfering surfaces to enhance torque resistance therebetween.
Abstract translation: 公开了一种用于脐带驱动流体处理离心机系统的脐带，以及一种制造它的方法和包括这种肚脐的流体流动回路。 脐部包括细长的肚脐体，限定内腔的第一端配件，容纳在内腔内的适配器，并且具有延伸到脐体的流体传送腔的至少一个端口延伸部，适配器和端部配件包括干涉表面 以增强它们之间的扭矩阻力。
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10.发明申请公开(公告)号：US20170029776A1
公开(公告)日：2017-02-02
申请号：US14810058
申请日：2015-07-27
Applicant: Fenwal, Inc.
CPC classification number: C12N5/0641 , A61L2/0047 , A61L2202/14 , A61L2202/22 , A61M1/0209 , A61M1/3681 , A61M1/3683 , A61M1/3696 , A61M2205/051 , A61M2205/12 , A61M2205/15 , A61M2205/3306 , C12M37/00 , C12M41/48
Abstract: An irradiation device includes a fluid treatment chamber configured to receive a biological fluid container, the fluid treatment chamber having opposing first and second sides, at least one light source disposed adjacent at least one of the first and second sides of the fluid treatment chamber, and an overflow reservoir in fluid communication with the fluid treatment chamber to receive fluid leaking from the biological fluid container. The device also includes a non-contact sensor disposed adjacent the overflow reservoir and configured to generate a signal according to leaked fluid in the overflow reservoir, an indicator, and a controller coupled to the at least one light source, the non-contact sensor and the indicator, the controller configured to activate the indicator upon receipt of the signal from the sensor and to deactivate the at least one light source subsequent to receipt of the signal from the sensor.
Abstract translation: 照射装置包括被配置为容纳生物流体容器的流体处理室，所述流体处理室具有相对的第一和第二侧，邻近流体处理室的第一和第二侧中的至少一个设置的至少一个光源，以及 与所述流体处理室流体连通以接收从所述生物流体容器泄漏的流体的溢流储存器。 该装置还包括非接触式传感器，该非接触式传感器邻近溢流容器设置，并被配置为根据溢流储存器中的泄漏流体产生信号，指示器和耦合到至少一个光源，非接触式传感器和 所述指示器，所述控制器被配置为在从所述传感器接收到所述信号时激活所述指示器，并且在从所述传感器接收到所述信号之后停用所述至少一个光源。
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