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公开(公告)号：US12090256B2
公开(公告)日：2024-09-17
申请号：US16488724
申请日：2017-04-20
申请人： Fenwal, Inc.
CPC分类号： A61M1/0218 , A61M1/3622 , A61M1/36225 , A61M1/362265 , A61M1/3693 , A61J1/10 , A61M2202/0427 , A61M2205/123 , A61M2205/125 , A61M2205/7545
摘要： Systems and methods are provided for collecting a platelet product from a fluid including platelets and plasma. Platelet-rich plasma is separated from at least a portion of another constituent of the fluid and then may be further separated into concentrated platelets and platelet-poor plasma, with the concentrated platelets being resuspended. Separated platelets are conveyed through a size exclusion filter and into a platelet storage container. The size exclusion filter is configured to remove platelet clumps and/or particles larger than a platelet from the separated platelets. Subsequently, an additive is conveyed through the size exclusion filter and into the platelet storage container. Conveying additive through the size exclusion filter improves platelet recovery in the platelet product by displacement of separated platelets with the additive and may also break up any platelet clumps that are present in the size exclusion filter.
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公开(公告)号：US11911553B2
公开(公告)日：2024-02-27
申请号：US16442671
申请日：2019-06-17
申请人： Fenwal, Inc.
CPC分类号： A61M1/3692 , A61M1/0272 , A61M1/0281 , A61M1/3693 , A61M1/362227 , A61M1/362265 , B01L3/502 , A61M1/36224 , B01L2400/0409
摘要： A system for concentrating cells, wherein a syringe comprises a lumen and an axial end comprising a port and a radial end closed to liquid flow. A plunger divides the axial and radial ends, and the syringe is configured to hold a cellular suspension. A filter disposed at the radial end is configured to maintain sterility of the syringe. A cap comprises a vent disposed at the radial end. The plunger is configured to be actuated towards the axial end by air pressure being applied into the radial end and the plunger is configured to be actuated towards the radial end by a vacuum being applied into the radial end.
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3.发明授权公开(公告)号：US11850604B2
公开(公告)日：2023-12-26
申请号：US17934650
申请日：2022-09-23
申请人： Fenwal, Inc.
CPC分类号： B04B11/02 , A61M1/36224 , A61M1/36225 , A61M1/362227 , A61M1/362261 , A61M1/362265 , B04B5/0442 , A61M1/3693 , A61M2202/0415 , A61M2230/30 , B04B2013/006
摘要： A fluid separation device includes a centrifuge in which a fluid is separated into at least two components, with an interface therebetween. At least a portion of one of the separated fluid components is removed from the centrifuge and flows through a vessel. Light is reflected off of the separated fluid component in the vessel and received and analyzed to determine its main wavelength. If the main wavelength is higher than a maximum value, a target location of the interface is changed. If the main wavelength is less than the maximum value, then the location of the interface is compared to the target location. When the interface is sufficiently close to the target location, the optical density of the separated fluid component in the vessel is compared to a minimum value. If the optical density is less than the minimum value, the target location of the interface is changed.
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公开(公告)号：US11826677B2
公开(公告)日：2023-11-28
申请号：US17700973
申请日：2022-03-22
申请人： Fenwal, Inc.
发明人： Benjamin E. Kusters , Kyungyoon Min
CPC分类号： B01D21/262 , A61M1/36224 , A61M1/36225 , A61M1/362227 , A61M1/362261 , A61M1/362265 , A61M1/362266 , B01D21/34 , G01N35/00584 , A61M1/362264 , G01N2035/00495
摘要： Blood in a separation chamber is separated into a red blood cell layer, a plasma constituent, and a mononuclear cell-containing layer. A portion of the plasma constituent exits the chamber via a plasma outlet, while a first portion of the red blood cell layer exits via a red blood cell outlet. A second portion of the red blood cell layer exits the chamber via the red blood cell outlet and is collected. At least a portion of the collected red blood cell layer may then be conveyed to the chamber via the red blood cell outlet to convey at least a portion of the mononuclear cell-containing layer out of the chamber via the plasma outlet for collection. A second portion of the plasma constituent may be conveyed out of the chamber via the plasma outlet to more fully collect the mononuclear cell-containing layer without the use of collected plasma.
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公开(公告)号：US20230218807A1
公开(公告)日：2023-07-13
申请号：US18125094
申请日：2023-03-22
申请人： Fenwal, Inc.
发明人： Benjamin E. Kusters , Kyungyoon Min
CPC分类号： A61M1/1603 , A61M1/0272 , A61M1/306 , A61M1/367 , A61M1/3693 , A61M1/3696 , A61M5/16845 , A61M5/16854 , A61M1/3403 , A61M2205/14 , A61M2205/15 , A61M2205/3331 , A61M2205/3334 , A61M2205/3393
摘要： A computer-implemented method comprises providing a fluid circuit comprising fluid pathways configured to mount and associate with a durable processing device comprising a pressure sensor in communication with a controller and a fluid pathway. A container is connected to the pressure sensor and may receive a volume of fluid. A change in pressure values between a first and second time is measured from when the volume of fluid is not in communication with the pressure sensor to when the volume of fluid is in communication with the pressure sensor, the volume of fluid within the container or a presence or absence of a fluid connection to the fluid pathway based on the change in pressure values is determined, and a response action is executed if the volume of fluid within the container is not within an authorized volume range for the time period, or if a fluid connection is unauthorized.
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公开(公告)号：US11676715B2
公开(公告)日：2023-06-13
申请号：US17865038
申请日：2022-07-14
申请人： Fenwal, Inc.
发明人： Brian C. Case , Jonathan Prendergast , John W. Barry, Jr. , Kyungyoon Min , Christopher D. Gassman , Daryl Richard Calhoun
IPC分类号： G16H40/63 , G06Q10/087 , G06Q10/1093 , G16H10/60 , G16H40/67 , G06T11/20
CPC分类号： G16H40/63 , G06Q10/087 , G06Q10/1093 , G06T11/206 , G16H10/60 , G16H40/67
摘要： A system and method for collecting whole blood from blood donors includes first and second whole blood collection devices disposed at different blood donation centers. A remote server computer is in communication with the blood collection devices. The whole blood collection devices transfer donation procedure information to the remote server. The remote server computer facilitates retrieval of the donation procedure information at a handheld computing device. The donation procedure information includes data based on product volume collected and data indicating performance of operators of the whole blood collection devices. The handheld computing device displays a number of whole blood units collected. Blood collection can be improved using the donation procedure information.
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公开(公告)号：US20220400992A1
公开(公告)日：2022-12-22
申请号：US17861437
申请日：2022-07-11
申请人： FENWAL, INC.
发明人： Amit J. Patel , Samantha M. Planas , Walter T. Watts , Kyungyoon Min , Daniel R. Boggs , Katherine N. Radwanski
IPC分类号： A61B5/15
摘要： A plasmapheresis system and a method for operating a plasmapheresis system are provided by which a volume of plasma product (i.e., anticoagulated plasma) so that that the targeted volume of pure plasma in the plasma product is determined based on donor-specific characteristics. In particular, the targeted amount of pure plasma to be collected is based on the weight, or the weight and the height, of the donor. The targeted volume of pure plasma to be collected, TVP, may be a multiple of the donor's weight. Alternatively, TVP may be a multiple of the donor's total blood volume, TBV, with the TBV of the donor being determined based on the donor's weight and height. A target volume for the plasma product to be collected, TVPP, is established, and separation of whole blood into a plasma component and a second component continues until the volume of plasma product in a collection container equals TVPP.
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8.发明授权公开(公告)号：US11484891B2
公开(公告)日：2022-11-01
申请号：US16878650
申请日：2020-05-20
申请人： Fenwal, Inc.
摘要： A fluid separation device includes a centrifuge in which a fluid is separated into at least two components, with an interface therebetween. At least a portion of one of the separated fluid components is removed from the centrifuge and flows through a vessel. Light is reflected off of the separated fluid component in the vessel and received and analyzed to determine its main wavelength. If the main wavelength is higher than a maximum value, a target location of the interface is changed. If the main wavelength is less than the maximum value, then the location of the interface is compared to the target location. When the interface is sufficiently close to the target location, the optical density of the separated fluid component in the vessel is compared to a minimum value. If the optical density is less than the minimum value, the target location of the interface is changed.
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公开(公告)号：US20220262506A1
公开(公告)日：2022-08-18
申请号：US17732073
申请日：2022-04-28
申请人： Fenwal, Inc.
摘要： A system and method processes blood donation data for presentation on an operator interface. A handheld computing device has a touch screen display and a processing circuit to provide an icon associated with an executable application on a first display screen, the icon configured to be positioned along with icons for other executable applications on the first display screen. The processing circuit is to retrieve an indication of a need for a particular blood component, wherein the particular blood component is selected from the group comprising whole blood, double red cells and plasma. The processing circuit is to provide the indication of the need for a particular blood component to the display. The processing circuit is to provide to the touch screen display a remaining time or a date the blood donor is next eligible to donate a blood component based on a donation eligibility guideline.
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公开(公告)号：US11412967B2
公开(公告)日：2022-08-16
申请号：US17306099
申请日：2021-05-03
申请人： Fenwal, Inc.
发明人： Amit J. Patel , Samantha M. Planas , Walter T. Watts , Kyungyoon Min , Daniel R. Boggs , Katherine N. Radwanski
IPC分类号： A61B5/15
摘要： A plasmapheresis system and a method for operating a plasmapheresis system are provided by which a volume of plasma product (i.e., anticoagulated plasma) so that that the targeted volume of pure plasma in the plasma product is determined based on donor-specific characteristics. In particular, the targeted amount of pure plasma to be collected is based on the weight, or the weight and the height, of the donor. The targeted volume of pure plasma to be collected, TVP, may be a multiple of the donor's weight. Alternatively, TVP may be a multiple of the donor's total blood volume, TBV, with the TBV of the donor being determined based on the donor's weight and height. A target volume for the plasma product to be collected, TVPP, is established, and separation of whole blood into a plasma component and a second component continues until the volume of plasma product in a collection container equals TVPP.
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