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公开(公告)号:US12116638B2
公开(公告)日:2024-10-15
申请号:US17673718
申请日:2022-02-16
发明人: Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC分类号: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/28
CPC分类号: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
摘要: Novel mutant ESR1 molecules and uses are disclosed.
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公开(公告)号:US11771698B2
公开(公告)日:2023-10-03
申请号:US17204830
申请日:2021-03-17
发明人: Siraj Mahamed Ali , Matthew J. Hawryluk , Jie He , Doron Lipson , Vincent A. Miller , Jeffrey S. Ross , Philip James Stephens
IPC分类号: A61K31/517 , A61K31/498 , A61K31/19 , A61K31/5025 , C12N9/12 , A61K31/4412 , A61K45/06 , A61K31/47 , A61K31/435 , A61K31/506 , A61K31/519 , A61K31/4439 , A61K31/53 , A61K31/404 , A61K31/5383 , A61K31/496 , C12Q1/6886 , A61K31/553 , C07K14/705 , C07K14/71 , C07K16/40 , C12N15/113 , C12Q1/6883 , G01N33/573
CPC分类号: A61K31/5025 , A61K31/404 , A61K31/435 , A61K31/4412 , A61K31/4439 , A61K31/47 , A61K31/496 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/53 , A61K31/5383 , A61K31/553 , A61K45/06 , C07K14/705 , C07K14/71 , C07K16/40 , C12N9/12 , C12N15/1137 , C12Q1/6883 , C12Q1/6886 , C12Y207/10001 , G01N33/573 , C07K2319/00 , C12N2310/11 , C12N2310/12 , C12N2310/14 , C12Q2600/156 , C12Q2600/158 , G01N2333/912 , G01N2500/04
摘要: Methods and compositions for treating cholangiocarcinoma.
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公开(公告)号:US20180320238A1
公开(公告)日:2018-11-08
申请号:US15877035
申请日:2018-01-22
发明人: Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC分类号: C12Q1/6886 , A61K31/675 , A61K31/565 , A61K31/436 , A61K31/4439 , C07K16/28 , A61K31/416 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/472 , A61K31/536 , A61K31/5415 , C07K14/72 , A61K31/567 , A61K45/06 , A61K31/439 , A61K31/4196
CPC分类号: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
摘要: Novel mutant ESR1 molecules and uses are disclosed.
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公开(公告)号:US10093983B2
公开(公告)日:2018-10-09
申请号:US14753397
申请日:2015-06-29
发明人: Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC分类号: G01N33/53 , C12Q1/6886 , A61K31/4196 , A61K31/565 , A61K31/675 , A61K31/439 , A61K31/567 , A61K31/416 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K45/06 , C07K14/72 , C07K16/28 , A61K31/436
摘要: Novel mutant ESR1 molecules and uses are disclosed.
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公开(公告)号:US11286532B2
公开(公告)日:2022-03-29
申请号:US15877035
申请日:2018-01-22
发明人: Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC分类号: C12Q1/6886 , A61K31/565 , A61K31/4196 , A61K31/675 , A61K31/439 , A61K31/567 , A61K31/416 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K45/06 , C07K14/72 , C07K16/28 , A61K31/436
摘要: Novel mutant ESR1 molecules and uses are disclosed.
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公开(公告)号:US09861633B2
公开(公告)日:2018-01-09
申请号:US14333368
申请日:2014-07-16
IPC分类号: C12Q1/68 , A61K31/517 , A61K47/48 , A61K31/5365 , C07K14/82 , C07K16/32 , A61K45/06 , A61K31/475 , A61K31/519 , A61K31/704 , A61K31/7105 , A61K31/713 , A61K33/24
CPC分类号: A61K31/517 , A61K31/475 , A61K31/519 , A61K31/5365 , A61K31/704 , A61K31/7105 , A61K31/713 , A61K33/24 , A61K45/06 , A61K47/6803 , A61K47/6851 , A61K47/6855 , C07K14/82 , C07K16/32 , C12Q1/6886 , C12Q2600/106 , A61K2300/00
摘要: Methods and compositions for treating a urothelial and/or a micropapillary carcinoma, such as a micropapillary urothelial carcinoma are disclosed.
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公开(公告)号:US20160145691A1
公开(公告)日:2016-05-26
申请号:US14753397
申请日:2015-06-29
发明人: Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC分类号: C12Q1/68 , A61K45/06 , C07K16/28 , C07K14/72 , A61K31/5415 , A61K31/437 , A61K31/423 , A61K31/428 , A61K31/472 , A61K31/536 , A61K31/416 , A61K31/4439
CPC分类号: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
摘要: Novel mutant ESR1 molecules and uses are disclosed.
摘要翻译: 公开了新型突变体ESR1分子和用途。
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公开(公告)号:US20190233897A1
公开(公告)日:2019-08-01
申请号:US16122286
申请日:2018-09-05
发明人: Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC分类号: C12Q1/6886 , A61K31/675 , A61K31/4196 , A61K31/439 , A61K45/06 , A61K31/567 , A61K31/565 , A61K31/436 , A61K31/4439 , C07K16/28 , A61K31/416 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/472 , A61K31/536 , A61K31/5415 , C07K14/72
CPC分类号: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
摘要: Novel mutant ESR1 molecules and uses are disclosed.
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公开(公告)号:US09610288B2
公开(公告)日:2017-04-04
申请号:US14333368
申请日:2014-07-16
IPC分类号: C12Q1/68 , A61K31/517 , A61K47/48 , A61K31/5365 , C07K14/82 , C07K16/32 , A61K45/06 , A61K31/475 , A61K31/519 , A61K31/704 , A61K31/7105 , A61K31/713 , A61K33/24
摘要: Methods and compositions for treating a urothelial and/or a micropapillary carcinoma, such as a micropapillary urothelial carcinoma are disclosed.
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公开(公告)号:US20150366866A1
公开(公告)日:2015-12-24
申请号:US14761518
申请日:2014-01-17
发明人: Siraj Mahamed Ali , Matthew J. Hawryluk , Jie He , Doron Lipson , Vincent A. Miller , Jeffrey S. Ross , Philip James Stephens
IPC分类号: A61K31/5025 , C07K16/40 , C12Q1/68 , G01N33/573 , C12N9/12 , A61K31/4412 , C12N15/113
CPC分类号: A61K31/5025 , A61K31/404 , A61K31/435 , A61K31/4412 , A61K31/4439 , A61K31/47 , A61K31/496 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/53 , A61K31/5383 , A61K31/553 , A61K45/06 , C07K14/705 , C07K14/71 , C07K16/40 , C07K2319/00 , C12N9/12 , C12N15/1137 , C12N2310/11 , C12N2310/12 , C12N2310/14 , C12Q1/6883 , C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , C12Y207/10001 , G01N33/573 , G01N2333/912 , G01N2500/04
摘要: Methods and compositions for treating cholangiocarcinoma.
摘要翻译: 治疗胆管癌的方法和组合物。
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