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    TISSUE SITE MARKERS FOR IN VIVO IMAGING
    3.
    发明申请
    TISSUE SITE MARKERS FOR IN VIVO IMAGING 有权
    组织网站标记在VIVO成像

    公开(公告)号：US20100298698A1

    公开(公告)日：2010-11-25

    申请号：US12787177

    申请日：2010-05-25

    申请人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank R. Louw ,  Stephen A. DeSantis

    发明人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank R. Louw ,  Stephen A. DeSantis

    IPC分类号： A61B6/00

    CPC分类号： A61B19/54 ,  A61B6/12 ,  A61B8/0833 ,  A61B90/39 ,  A61B2090/08021 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61B2090/3991 ,  A61M37/0069

    摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

    摘要翻译： 本发明是针对活检部位标记和标记活检部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。 可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。

    Biopsy device with selectable tissue receiving aperture orientation and site illumination
    7.
    发明授权
    Biopsy device with selectable tissue receiving aperture orientation and site illumination 有权

    公开(公告)号：US10172595B2

    公开(公告)日：2019-01-08

    申请号：US12229553

    申请日：2008-08-25

    申请人： Martin V. Shabaz ,  Richard L. Quick ,  Frank R. Louw ,  Paul Lubock ,  Jason H. Safabash

    发明人： Martin V. Shabaz ,  Richard L. Quick ,  Frank R. Louw ,  Paul Lubock ,  Jason H. Safabash

    IPC分类号： A61B10/02 ,  A61B90/00 ,  A61B90/30 ,  B23Q17/24 ,  F21V33/00 ,  A61B17/00 ,  A61B17/34 ,  A61B17/32

    摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.

    BIOPSY DEVICE WITH INNER CUTTING MEMBER
    9.
    发明申请
    BIOPSY DEVICE WITH INNER CUTTING MEMBER 有权
    具有内切刀的生物装置

    公开(公告)号：US20100262037A1

    公开(公告)日：2010-10-14

    申请号：US12793465

    申请日：2010-06-03

    申请人： Richard L. Quick ,  Frank R. Louw ,  Paul Lubock ,  Martin V. Shabaz

    发明人： Richard L. Quick ,  Frank R. Louw ,  Paul Lubock ,  Martin V. Shabaz

    IPC分类号： A61B10/02

    CPC分类号： A61B10/0233 ,  A61B10/02 ,  A61B10/0266 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/3417 ,  A61B90/30 ,  A61B90/39 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/0046 ,  A61B2017/00473 ,  A61B2017/3405 ,  A61B2017/3454 ,  A61B2090/0811 ,  A61B2090/309 ,  B23Q17/2404 ,  F21V33/0068

    摘要： The invention is directed to devices and methods for separating and collecting a tissue specimen from a patient's target site. The device includes a probe member with a penetrating distal tip and a tissue receiving aperture, and a tissue cutting member which is rotatable disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture. The longitudinal edges of the aperture are preferably sharpened to engage the cutting edges of the tissue cutting member. Vacuum may be provided in the inner lumen of the cutting member to transport tissue therethrough. Rotation, rotational oscillation and/or longitudinal reciprocation of the tissue cutting member is effective to separate a tissue specimen from surrounding tissue. An accessing cannula having an tissue receiving aperture may be concentrically disposed within the probe member and about the tissue cutting member. The tissue cutting edge of the tissue cutting member preferably is longitudinally oriented and may have a cutting angle less than 90° with respect to the longitudinal axis of the tissue cutting member.

    摘要翻译： 本发明涉及用于从患者的目标部位分离和收集组织标本的装置和方法。 该装置包括具有穿透性远侧末端和组织接收孔的探针构件，以及组织切割构件，该组织切割构件可旋转地设置在探针构件内，以通过孔切割被拉入装置内部的组织样本。 孔的纵向边缘优选地被锐化以接合组织切割构件的切割边缘。 可以在切割构件的内腔中设置真空以将组织输送通过其中。 组织切割构件的旋转，旋转振动和/或纵向往复运动有效地将组织标本与周围组织分开。 具有组织接收孔的进入套管可以同心地设置在探针构件内并且围绕组织切割构件。 组织切割构件的组织切割边缘优选地纵向定向并且可以具有相对于组织切割构件的纵向轴线小于90°的切割角度。

    Tissue cutting member for a biopsy device
    10.
    发明授权
    Tissue cutting member for a biopsy device 有权
    用于活检装置的组织切割构件

    公开(公告)号：US09095325B2

    公开(公告)日：2015-08-04

    申请号：US11438955

    申请日：2006-05-22

    申请人： Paul Lubock ,  Frank R. Louw ,  Richard L. Quick

    发明人： Paul Lubock ,  Frank R. Louw ,  Richard L. Quick

    IPC分类号： A61B10/00 ,  A61B10/02 ,  A61B17/32 ,  A61B17/34

    CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B17/320016 ,  A61B17/3417

    摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.

    摘要翻译： 本发明涉及具有这种组织切割构件的组织切割构件和活检装置，用于在目标部位处将组织标本与患者的身体分离。 组织切割构件可滑动地设置在活检装置的细长探针构件的内腔中，以通过探针中的组织接收孔切割拉入活检装置的外套管内部的组织样本。 组织切割构件具有管状远端部分，远侧末端具有外部组织切割边缘，内部组织接收孔和纵向定向的开口，其具有封闭的近端和敞开的远端，其通向内部组织接收孔以便于 远端管状部分的扩口。 切割构件在管状部分的壁中具有至少一个开口，以在使用期间保持真空。