-
公开(公告)号：US06559145B2
公开(公告)日：2003-05-06
申请号：US09887794
申请日：2001-06-22
IPC分类号： A61K31536
CPC分类号： C07D285/16 , C07D265/22 , C07D279/02 , C07D311/22 , C07D333/58 , C07D471/04 , C07D495/04 , C07D513/04
摘要： The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
摘要翻译： 本发明提供式I化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。
-
公开(公告)号：US06624159B2
公开(公告)日：2003-09-23
申请号：US09887578
申请日：2001-06-22
申请人： David John Anderson , Gordon L. Bundy , Fred L. Ciske , David R. Graber , Michael J. Genin , Thomas M. Judge , Malcolm Wilson Moon , Mark E. Schnute , Joseph Walter Strohbach , Suvit Thaisrivongs , Atli Thorarensen , Steven Ronald Turner , Valerie A. Vaillancourt , Allison J. Wolf
发明人： David John Anderson , Gordon L. Bundy , Fred L. Ciske , David R. Graber , Michael J. Genin , Thomas M. Judge , Malcolm Wilson Moon , Mark E. Schnute , Joseph Walter Strohbach , Suvit Thaisrivongs , Atli Thorarensen , Steven Ronald Turner , Valerie A. Vaillancourt , Allison J. Wolf
IPC分类号： C07D47106
CPC分类号： C07D471/06
摘要： The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
-
公开(公告)号：US06903097B2
公开(公告)日：2005-06-07
申请号：US10323027
申请日：2002-12-18
IPC分类号： A61K31/353 , A61K31/4025 , A61K31/4375 , A61K31/5025 , A61K31/519 , A61K31/536 , A61K31/5377 , A61K31/5415 , A61K31/542 , A61K31/549 , A61P31/22 , C07D265/02 , C07D265/22 , C07D279/02 , C07D285/16 , C07D311/22 , C07D333/58 , C07D405/06 , C07D471/04 , C07D495/04 , C07D513/04 , A61K31/53 , A61P43/00 , C07D251/02
CPC分类号： C07D285/16 , C07D265/22 , C07D279/02 , C07D311/22 , C07D333/58 , C07D471/04 , C07D495/04 , C07D513/04
摘要： The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
摘要翻译： 本发明提供式I化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。
-
![4-Oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents](/abs-image/US/2004/12/14/US06831081B2/abs.jpg.150x150.jpg)
4.发明授权4-Oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents 失效4-氧代-4,7-二氢噻吩并[2,3-b]吡啶-5-甲酰胺作为抗病毒剂公开(公告)号：US06831081B2
公开(公告)日：2004-12-14
申请号：US10649298
申请日：2003-08-27
申请人： Mark E. Schnute , Fred L. Ciske , Michael J. Genin , Joseph Walter Strohbach , Suvit Thaisrivongs
发明人： Mark E. Schnute , Fred L. Ciske , Michael J. Genin , Joseph Walter Strohbach , Suvit Thaisrivongs
IPC分类号： A61K31435
CPC分类号： C07D495/04
摘要： The present invention provides a compound of formula as described herein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.
摘要翻译： 本发明提供了本文所述的式的化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。
-
公开(公告)号：US06248739B1
公开(公告)日：2001-06-19
申请号：US09466712
申请日：1999-12-17
申请人： Steven Ronald Turner , Joseph Walter Strohbach , Suvit Thaisrivongs , Valerie A. Vaillancourt , Mark E. Schnute , John Alan Tucker
发明人： Steven Ronald Turner , Joseph Walter Strohbach , Suvit Thaisrivongs , Valerie A. Vaillancourt , Mark E. Schnute , John Alan Tucker
IPC分类号： A61K31535
CPC分类号： C07D215/227 , C07D215/24 , C07D215/36 , C07D215/38 , C07D215/56 , C07D215/58 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/04 , C07D491/08
摘要： The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
摘要翻译： 本发明提供式I化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。
-
公开(公告)号：US06248736B1
公开(公告)日：2001-06-19
申请号：US09465670
申请日：1999-12-17
申请人： Steven Ronald Turner , Joseph Walter Strohbach , Suvit Thaisrivongs , Valerie A. Vaillancourt , Mark E. Schnute , Allen Scott
发明人： Steven Ronald Turner , Joseph Walter Strohbach , Suvit Thaisrivongs , Valerie A. Vaillancourt , Mark E. Schnute , Allen Scott
IPC分类号： A61K3154
CPC分类号： C07D215/56
摘要： The present invention provides a compound of formula I Wherein R1 is C1-7 alkyl, optionally substituted by hydroxy or NR4R5; R2 is C1-7 alkyl substituted by hydroxy or NR4R5; R3 is H, F or C1-7 alkoxy; R4 and R5 together with N are a 5- or 6-membered heterocyclic moiety having 1-3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur in which sulfur may be substituted by one (1) or two (2) oxygen atoms; and pharmaceutically acceptable salts thereof Compounds of formula I of the present invention are useful as antiviral agents.
摘要翻译： 本发明提供式I化合物，其中R 1为任选被羟基或NR 4 R 5取代的C 1-7烷基; R2是被羟基或NR4R5取代的C1-7烷基; R3是H，F或C1-7烷氧基; R 4和R 5与N一起是具有1-3个选自氮，氧和硫的杂原子的5-或6-元杂环部分，其中硫可以被一个（1）或两个（2）氧原子取代 ; 本发明式I化合物可用作抗病毒剂。
-
7.发明授权
公开(公告)号：US6093732A
公开(公告)日：2000-07-25
申请号：US203259
申请日：1998-12-01
申请人： John Alan Tucker , Valerie A. Vaillancourt , Joseph Walter Strohbach , Karen Rene Romines , Mark E. Schnute , Michele M. Cudahy , Suvit Thaisrivongs , Steven Ronald Turner
发明人： John Alan Tucker , Valerie A. Vaillancourt , Joseph Walter Strohbach , Karen Rene Romines , Mark E. Schnute , Michele M. Cudahy , Suvit Thaisrivongs , Steven Ronald Turner
IPC分类号： A61K31/47 , A61K31/4709 , A61K31/473 , A61K31/4738 , A61K31/4745 , A61P31/12 , A61P31/22 , C07D215/56 , C07D221/16 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D413/04 , C07D417/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D491/056 , C07D513/04 , C07F7/10 , C07F9/60 , C07D215/00
CPC分类号： C07F9/60 , C07D215/56 , C07D221/16 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D413/04 , C07D417/04 , C07D417/12 , C07D487/04 , C07D513/04
摘要： The present invention provides 4-hydroxyquinoline-3-carboxamide and hydrazide compounds of formula I ##STR1## These compounds are useful to treat or prevent the herpesviral infections, particularly, human cytomegaloviral infection.
摘要翻译： 本发明提供式I的4-羟基喹啉-3-甲酰胺和酰肼化合物。这些化合物可用于治疗或预防疱疹病毒感染，特别是人巨细胞病毒感染。
-
公开(公告)号：US06730682B2
公开(公告)日：2004-05-04
申请号：US09887620
申请日：2001-06-22
IPC分类号： A61K3152
CPC分类号： C07D405/06 , C07D217/14 , C07D217/26 , C07D471/04
摘要： The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
摘要翻译： 本发明提供式I化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。
-
9.发明申请HETERO BICYCLIC CARBOXAMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS 审中-公开异双环酰胺酰胺衍生物及其药物用途和组合物公开(公告)号：US20110009435A1
公开(公告)日：2011-01-13
申请号：US12663157
申请日：2008-05-19
申请人： Mark E. Schnute , Peter G. Ruminski , Cathleen E. Hanau , Joseph W. Stobach , Jeffery Carroll , Kirby Sample
发明人： Mark E. Schnute , Peter G. Ruminski , Cathleen E. Hanau , Joseph W. Stobach , Jeffery Carroll , Kirby Sample
IPC分类号： A61K31/517 , C07D491/04 , C07D239/72 , A61K31/519 , A61P37/00 , A61P17/06 , A61P19/02 , A61P35/00 , A61P11/00 , A61P11/06 , A61P1/06
CPC分类号： C07D239/90 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D495/04
摘要： The present invention relates to compounds of Formula I and pharmaceutically acceptable salts thereof, processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as anti-inflammatory agents.
摘要翻译： 本发明涉及式I化合物及其药学上可接受的盐，其制备方法，用于制备的中间体和含有这些化合物的组合物以及这些化合物作为抗炎剂的用途。
-
![4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5carboxamides as antiviral agents](/abs-image/US/2001/05/29/US06239142B1/abs.jpg.150x150.jpg)
10.发明授权4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5carboxamides as antiviral agents 失效4-氧代-4,7-二氢 - 噻吩并[2,3-b]吡啶-5-甲酰胺作为抗病毒剂公开(公告)号：US06239142B1
公开(公告)日：2001-05-29
申请号：US09521027
申请日：2000-03-07
申请人： Mark E. Schnute , Michele M. Cudahy , Allen Scott
发明人： Mark E. Schnute , Michele M. Cudahy , Allen Scott
IPC分类号： A61K31435
CPC分类号： C07D495/04 , C07D333/38
摘要： The invention provides a compound of formula I: wherein R1, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of preventing or treating a herpesvirus infection using such compounds or salts.
摘要翻译： 本发明提供式I化合物：其中R1，R2，R3和R4具有说明书中定义的任何值，或其药学上可接受的盐，以及可用于制备这些化合物或盐的方法和中间体，以及 使用这些化合物或盐预防或治疗疱疹病毒感染的方法。
-
-
-
-
-
-
-
-
-
搜索结果
15 条记录 (耗时 0.029 秒)
