-
公开(公告)号：US20210178333A1
公开(公告)日：2021-06-17
申请号：US17189515
申请日：2021-03-02
申请人： GAMBRO LUNDIA AB
发明人： Bernd KRAUSE , Markus NEUBAUER , Joachim LOERCHER
IPC分类号： B01D67/00 , C12N5/00 , C12M1/12 , C12N5/0775
摘要： The invention relates to a membrane which can be used for cultivating adherent or suspension cells, in particular adherent cells, wherein said membrane allows for the adhesion and proliferation of the cells due to the irradiation of the wet or dry membrane with gamma- or beta-rays or an electron beam in a dose of from 12.5 to 175 kGy in the presence of oxygen. The resulting membrane may be used without any pre-treatment with surface-modifying substances. The invention further relates to a method for preparing said irradiated membrane which can be used for the cultivation of cells, in particular adherent cells, and to methods of using such a membrane for the cultivation of cells, in particular adherent cells.
-
公开(公告)号：US20200316533A1
公开(公告)日：2020-10-08
申请号：US16851439
申请日：2020-04-17
申请人： GAMBRO LUNDIA AB
发明人： Markus HORNUNG , Bernd KRAUSE , Markus STORR , Philipp HERBST , Arnd WOCHNER , Adriana BOSCHETTI-DE-FIERRO , Manuel VOIGT , Carina ZWEIGART , Joachim LOERCHER , Reinhold BUCK , Heinrich BEHR , Werner BECK
摘要： The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
-
公开(公告)号：US20200269197A1
公开(公告)日：2020-08-27
申请号：US16851432
申请日：2020-04-17
申请人： GAMBRO LUNDIA AB
发明人： Adriana BOSCHETTI-DE-FIERRO , Manuel VOIGT , Bernd KRAUSE , Markus HORNUNG , Markus STORR , Heinrich BEHR , Werner BECK , Carina ZWEIGART , Reinhold BUCK , Philipp HERBST , Joachim LOERCHER , Arnd WOCHNER
摘要： The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
-
公开(公告)号：US20220152562A1
公开(公告)日：2022-05-19
申请号：US17590085
申请日：2022-02-01
申请人： GAMBRO LUNDIA AB
发明人： Adriana BOSCHETTI-DE-FIERRO , Manuel VOIGT , Bernd KRAUSE , Markus HORNUNG , Markus STORR , Heinrich BEHR , Werner BECK , Carina ZWEIGART , Reinhold BUCK , Philipp HERBST , Joachim LOERCHER , Arnd WOCHNER
摘要： The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
-
公开(公告)号：US20170165616A1
公开(公告)日：2017-06-15
申请号：US15116031
申请日：2015-02-05
申请人： GAMBRO LUNDIA AB
发明人： Adriana BOSCHETTI-DE-FIERRO , Manuel VOIGT , Bernd KRAUSE , Markus HORNUNG , Markus STORR , Heinrich BEHR , Werner BECK , Carina ZWEIGART , Reinhold BUCK , Philipp HERBST , Joachim LOERCHER , Arnd WOCHNER
摘要： The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
-
公开(公告)号：US20220152563A1
公开(公告)日：2022-05-19
申请号：US17590097
申请日：2022-02-01
申请人： GAMBRO LUNDIA AB
发明人： Markus HORNUNG , Bernd KRAUSE , Markus STORR , Philipp HERBST , Arnd WOCHNER , Adriana BOSCHETTI-DE-FIERRO , Manuel VOIGT , Carina ZWEIGART , Joachim LOERCHER , Reinhold BUCK , Heinrich BEHR , Werner BECK
摘要： The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
-
公开(公告)号：US20200276373A1
公开(公告)日：2020-09-03
申请号：US16762623
申请日：2018-12-10
申请人： GAMBRO LUNDIA AB
摘要： The present disclosure relates to capillary dialyzers for blood purification, in particular, capillary dialyzers suitable for home hemodialysis systems.
-
公开(公告)号：US20170165615A1
公开(公告)日：2017-06-15
申请号：US15115951
申请日：2015-02-05
申请人： GAMBRO LUNDIA AB
发明人： Markus HORNUNG , Bernd KRAUSE , Markus STORR , Philipp HERBST , Arnd WOCHNER , Adriana BOSCHETTI-DE-FIERRO , Manuel VOIGT , Carina ZWEIGART , Joachim LOERCHER , Reinhold BUCK , Heinrich BEHR , Werner BECK
摘要： The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
-
公开(公告)号：US20170043299A1
公开(公告)日：2017-02-16
申请号：US15307106
申请日：2015-04-30
申请人： GAMBRO LUNDIA AB
发明人： Bernd KRAUSE , Ralf MENDA , Christof BECK , Joachim LOERCHER , Adriana BOSCHETTI-DE-FIERRO , Rainer BLICKLE
CPC分类号： B01D69/087 , A61M1/1686 , B01D67/009 , B01D67/0095 , B01D67/0097 , B01D71/68 , B01D2323/345 , B01D2323/42
摘要： The present invention relates to porous hollow fiber membranes suitable for hemodialysis, hemodiafiltration or hemofiltration of blood and processes for their production involving UV irradiation of the membrane.
摘要翻译： 本发明涉及适用于血液透析，血液透析过滤或血液滤过的多孔中空纤维膜及涉及紫外线照射的生产方法。
-
公开(公告)号：US20160207009A1
公开(公告)日：2016-07-21
申请号：US14915520
申请日：2014-09-03
申请人： GAMBRO LUNDIA AB
发明人： Ralf MENDA , Martin REMPFER , Joachim LOERCHER
CPC分类号： B01D71/28 , B01D63/023 , B01D67/0011 , B01D69/06 , B01D69/08 , B01D71/68 , B01D2325/34
摘要： The present invention relates to membranes being suitable e.g. for hemodialysis, hemodiafiltration, or hemofiltration of blood. The invention also relates to a process for the production of the membranes; and to devices comprising the membranes.
摘要翻译： 本发明涉及例如适合的膜。 用于血液透析，血液透析滤过或血液滤过。 本发明还涉及一种生产膜的方法; 以及包括膜的装置。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.019 秒)