公开(公告)号：US20240237966A1

公开(公告)日：2024-07-18

申请号：US18623858

申请日：2024-04-01

Applicant: GE Precision Healthcare LLC

Inventor： Christopher Michael Puleo ,  Jeffrey Michael Ashe ,  David Andrew Shoudy ,  Victoria Eugenia Cotero ,  James Enrico Sabatini

IPC: A61B8/00 ,  A61N7/00

CPC classification number: A61B8/4236 ,  A61B8/4281 ,  A61N7/00 ,  A61N2007/0026

Abstract: Embodiments of the present disclosure relate to techniques for accurate positioning of an energy application device for neuromodulation treatment protocols. In one embodiment, a neuromodulation positioning patch is applied to a patient's skin. The energy application device is configured to couple to a frame of the neuromodulation positioning patch to position a transducer of the energy application device within an opening at a treatment position within the opening. In one embodiment, the frame is also configured to couple to a removable dock for an imaging probe that, when coupled to the removable dock and, in turn, the frame of the neuromodulation positioning patch, is configured to acquire image data through the opening to identify or verify a treatment position.

公开(公告)号：US20240090869A1

公开(公告)日：2024-03-21

申请号：US18520180

申请日：2023-11-27

Applicant: GE Precision Healthcare LLC

Inventor： David Andrew Shoudy ,  Craig Patrick Galligan ,  Weston Blaine Griffin ,  Jeffrey Michael Ashe ,  Warren Lee ,  James Enrico Sabatini

IPC: A61B8/00 ,  A61N7/00

CPC classification number: A61B8/4227 ,  A61B8/4254 ,  A61N7/00 ,  A61N2007/0026 ,  A61N2007/0052 ,  A61N2007/0078

Abstract: The present discussion relates to structures and devices to facilitate application of an ultrasound therapy beam to a target anatomic region in a replicable manner. In certain aspects, adjustable positioning structures are described that allow a general probe positioning structure to be configured for a specific patient in a manner that allows the device to be used repeatedly to target the anatomic region, even when in non-clinical settings. In other aspects, a probe positioning structure is fabricated that is specific to a respective patient anatomy, such that use of the probe positioning structure provides repeatable targeting of the target anatomic region, even when in non-clinical settings.

公开(公告)号：US20240001159A1

公开(公告)日：2024-01-04

申请号：US18467552

申请日：2023-09-14

Applicant: GE Precision Healthcare LLC

Inventor： John Frederick Graf ,  Christopher Michael Puleo ,  Jeffrey Michael Ashe ,  Victoria Eugenia Cotero ,  David Andrew Shoudy

IPC: A61N7/00

CPC classification number: A61N7/00 ,  A61N2007/0086 ,  A61N2007/0026 ,  A61N2007/0052

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue at multiple regions of interest, concurrently or consecutively. The neuromodulation may result in tissue displacement, which may be observed through changes in one or more molecules of interest.

公开(公告)号：US20240189629A1

公开(公告)日：2024-06-13

申请号：US18587341

申请日：2024-02-26

Applicant: GE Precision Healthcare LLC

Inventor： Christopher Michael Puleo ,  Yang Zhao ,  Kirk Dennis Wallace ,  Ying Fan ,  Jeffrey Michael Ashe ,  David Andrew Shoudy

IPC: A61N7/00 ,  A61B8/00 ,  A61B90/00

CPC classification number: A61N7/00 ,  A61B8/4245 ,  A61B8/4254 ,  A61B90/361 ,  A61B90/37 ,  A61B8/4209 ,  A61B8/4263 ,  A61N2007/0026 ,  A61N2007/0052

Abstract: Embodiments of the present disclosure relate to techniques for facilitating personalized neuromodulation treatment protocols. In one embodiment, a predetermined treatment position of an energy application device is used to guide future treatments for the patient. In one embodiment, a position of the energy application device relative to the predetermined treatment position is determined. In one embodiment, a total dose of ultrasound energy applied to the region of interest is determined.

公开(公告)号：US20230218276A1

公开(公告)日：2023-07-13

申请号：US18179834

申请日：2023-03-07

Applicant: GE Precision Healthcare LLC

Inventor： Asha Singanamalli ,  David Andrew Shoudy ,  Jeffrey Michael Ashe ,  Christopher Michael Puleo

IPC: A61B5/00 ,  A61B5/02

CPC classification number: A61B5/0033 ,  A61B5/02 ,  A61B5/7267

Abstract: Embodiments of the present disclosure relate to techniques for neuromodulation delivery. Based on image data acquired from the subject, control parameters controlling energy application of neuromodulating energy may be dynamically changed during the course of the delivery to maintain desired characteristics of the neuromodulating energy. For example, the beam of the neuromodulating energy may be dynamically adjusted to account for movement of an organ during breathing. In another embodiment, a desired region of interest is identified within the subject based on a trained neural network and the acquired image data.