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公开(公告)号：US11274336B2
公开(公告)日：2022-03-15
申请号：US15912962
申请日：2018-03-06
发明人： Michael J. Gilly , Sangeetha Vijaysri Nair , James M. Carrick , Xianqun Wang , Susan K. Yamagata
IPC分类号： C12Q1/6844 , G16B40/00 , C12Q1/6851
摘要： Method and system for quantifying target nucleic acids using real-time amplification and internal calibration adjustment. The invention employs dual reference calibration curves for approximating a complete calibration curve from only a single adjustment calibrator amplified on the instrument that is to be calibrated.
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公开(公告)号：US09932628B2
公开(公告)日：2018-04-03
申请号：US13952338
申请日：2013-07-26
发明人： Michael J. Gilly , Sangeetha Vijaysri Nair , James M. Carrick , Xianqun Wang , Susan K. Yamagata
CPC分类号： C12Q1/6844 , C12Q1/6851 , G06F19/24 , C12Q2537/165
摘要： Method and system for quantifying target nucleic acids using real-time amplification and internal calibration adjustment. The invention employs dual reference calibration curves for approximating a complete calibration curve from only a single adjustment calibrator amplified on the instrument that is to be calibrated.
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公开(公告)号：US20240318241A1
公开(公告)日：2024-09-26
申请号：US18733583
申请日：2024-06-04
IPC分类号： C12Q1/6865 , C12Q1/70 , G16B20/00 , G16B40/00
CPC分类号： C12Q1/6865 , G16B20/00 , G16B40/00 , C12Q1/703
摘要： Presented are methods, systems, and software products useful for determining the concentration of an analyte in a fluid specimen used to produce a dried sample, where the dried sample serves as a source of the analyte in a detection and quantification procedure. Particularly illustrated is the use of dried blood spots for quantifying a polynucleotide analyte.
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公开(公告)号：US12037638B2
公开(公告)日：2024-07-16
申请号：US17783231
申请日：2020-12-09
IPC分类号： G06F30/20 , C12Q1/6865 , G16B20/00 , G16B40/00 , C12Q1/70
CPC分类号： C12Q1/6865 , G16B20/00 , G16B40/00 , C12Q1/703 , C12Q1/6865 , C12Q2537/165 , C12Q2545/114 , C12Q2561/113 , C12Q2565/625
摘要： Presented are methods, systems, and software products useful for determining the concentration of an analyte in a fluid specimen used to produce a dried sample, where the dried sample serves as a source of the analyte in a detection and quantification procedure. Particularly illustrated is the use of dried blood spots for quantifying a polynucleotide analyte.
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公开(公告)号：US11781174B2
公开(公告)日：2023-10-10
申请号：US15955401
申请日：2018-04-17
IPC分类号： C12Q1/6844 , G16B40/00 , C12Q1/6851 , G16B40/10
CPC分类号： C12Q1/6844 , C12Q1/6851 , G16B40/00 , G16B40/10 , C12Q1/6851 , C12Q2537/165
摘要： Method and system for quantifying target nucleic acids using real-time amplification and internal calibration adjustment. The approach employs a single fixed data point in combination with a single adjustment calibrator amplified on the instrument that is to be calibrated for approximating a complete calibration curve.
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公开(公告)号：US20220154264A1
公开(公告)日：2022-05-19
申请号：US17591128
申请日：2022-02-02
发明人： Michael J. Gilly , Sangeetha Vijaysri Nair , James M. Carrick , Xianqun Wang , Susan K. Yamagata
IPC分类号： C12Q1/6844 , G16B40/00 , C12Q1/6851
摘要： Method and system for quantifying target nucleic acids using real-time amplification and internal calibration adjustment. The invention employs dual reference calibration curves for approximating a complete calibration curve from only a single adjustment calibrator amplified on the instrument that is to be calibrated.
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公开(公告)号：US09976175B2
公开(公告)日：2018-05-22
申请号：US14211565
申请日：2014-03-14
CPC分类号： C12Q1/6844 , C12Q1/6851 , G06F19/24 , C12Q2537/165
摘要： Method and system for quantifying target nucleic acids using real-time amplification and internal calibration adjustment. The approach employs a single fixed data point in combination with a single adjustment calibrator amplified on the instrument that is to be calibrated for approximating a complete calibration curve.
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