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公开(公告)号：US20140115729A1
公开(公告)日：2014-04-24
申请号：US14137927
申请日：2013-12-20
申请人： Genentech, Inc.
发明人： Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号： C07K16/42
CPC分类号： C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要： The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译： 本申请涉及凋亡性抗IgE抗体，编码它的核酸，其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号：US20180201679A1
公开(公告)日：2018-07-19
申请号：US15803495
申请日：2017-11-03
申请人： GENENTECH, INC.
发明人： Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
CPC分类号： C07K16/2803 , A61K39/39541 , A61K39/39558 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/92 , Y02A50/412
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US10544218B2
公开(公告)日：2020-01-28
申请号：US15349964
申请日：2016-11-11
申请人： Genentech, Inc.
发明人： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC分类号： A61K39/395 , A61K39/40 , A61K39/42 , C07K16/28 , A61K38/05 , A61K31/537 , C07K16/30 , A61K51/10 , G01N33/574 , A61K45/06 , A61K47/68 , C07K16/00 , C12P21/08 , A61K39/00
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20190276550A9
公开(公告)日：2019-09-12
申请号：US13973669
申请日：2013-08-22
申请人： Genentech, Inc.
发明人： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC分类号： C07K16/28 , A61K39/395 , A61K45/06
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20140335107A1
公开(公告)日：2014-11-13
申请号：US14219473
申请日：2014-03-19
申请人： GENENTECH, INC.
发明人： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson
IPC分类号： C07K16/28 , G01N33/574
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20140099260A1
公开(公告)日：2014-04-10
申请号：US13973669
申请日：2013-08-22
申请人： Genentech, Inc.
发明人： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC分类号： C07K16/28 , A61K45/06 , A61K39/395
CPC分类号： C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US11866496B2
公开(公告)日：2024-01-09
申请号：US17234695
申请日：2021-04-19
申请人： Genentech, Inc.
发明人： Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC分类号： C07K16/00 , C07K16/28 , C07K16/30 , A61K39/395 , A61K51/10 , A61K47/68 , C07K17/00 , A61K39/00
CPC分类号： C07K16/2803 , A61K39/39541 , A61K39/39558 , A61K47/6849 , A61K51/1027 , C07K16/2896 , C07K16/3061 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/92 , Y02A50/30
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US09896506B2
公开(公告)日：2018-02-20
申请号：US14734957
申请日：2015-06-09
申请人： Genentech, Inc.
发明人： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC分类号： C07K16/28 , C07K16/30 , A61K39/395 , A61K47/68 , A61K38/05 , A61K45/06 , A61K51/10 , G01N33/574 , A61K31/537 , A61K39/00
CPC分类号： C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals, including immunoconjugates comprising anti-CD79b cysteine-engineered antibody huMA79b.v28, and to methods of using those compositions of matter for the same.
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公开(公告)号：USRE48558E1
公开(公告)日：2021-05-18
申请号：US15908703
申请日：2018-02-28
申请人： GENENTECH, INC.
发明人： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC分类号： A61K51/00 , A61K39/44 , C07K19/00 , C07K16/28 , A61K47/68 , A61K31/537 , A61K38/05 , A61K39/395 , A61K45/06 , A61K51/10 , C07K16/30 , G01N33/574 , A61K39/00
摘要： The present invention is directed to compositions of matter comprising immunoconjugates comprising an anti-CD79b antibody comprising: (i) an HVR-L1 sequence of KASQSVDYEGDSFLN (SEQ ID NO: 194), (ii) an HVR-L2 sequence of AASNLES (SEQ ID NO: 195), (iii) an HVR-L3 sequence of QQSNEDPLT (SEQ ID NO: 196), (iv) an HVR-H1 sequence of GYTFSSYWIE (SEQ ID NO: 202), (v) an HVR-H2 sequence of GEILPGGGDTNYNEIFKG (SEQ ID NO: 203), and (vi) an HVR-H3 sequence of TRRVPIRLDY (SEQ ID NO: 204) and to methods of using those compositions of matter for the treatment of hematopoietic tumor in mammals.
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公开(公告)号：US10981987B2
公开(公告)日：2021-04-20
申请号：US15803495
申请日：2017-11-03
申请人： GENENTECH, INC.
发明人： Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC分类号： A61K51/00 , A61K39/395 , A61K39/40 , C07K16/28 , C07K16/30 , A61K51/10 , A61K47/68 , C07K16/00 , C12P21/08 , A61K39/00
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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