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公开(公告)号：US09244049B2
公开(公告)日：2016-01-26
申请号：US13888759
申请日：2013-05-07
Applicant: General Electric Company
Inventor： Yongjae Lee , Aghogho Atemu Obi , Seog Tae Kim , William Chester Platt , James William Bray , Yuri Alexeyevich Plotnikov , Jack Mathew Webster , Vasile Bogdan Neculaes
Abstract: A system for measuring nutritional parameters of food items is provided. The system includes a holding cavity. The system further includes a sensor assembly that includes a transmitter antenna and at least one receiver antenna. The transmitter antenna is configured to transmit signals to a food item in the holding cavity. The receiver antenna is configured to receive response signals from the food item. The system includes at least one switch coupled to each antenna. The switch, in a first state, is configured to set the sensor assembly to an electric potential equal to that of the holding cavity. In a second state, the switch is configured to couple the sensor assembly to a power source. The system also includes a processing unit to process the signals received to determine the nutritional parameters of the food item.
Abstract translation: 提供了一种用于测量食品营养参数的系统。 该系统包括一个保持腔。 该系统还包括传感器组件，其包括发射器天线和至少一个接收器天线。 发射机天线被配置为将信号发送到保持腔中的食物。 接收器天线被配置为从食品接收响应信号。 该系统包括耦合到每个天线的至少一个开关。 在第一状态下的开关被配置成将传感器组件设置成等于保持腔的电位。 在第二状态下，开关被配置成将传感器组件耦合到电源。 该系统还包括处理单元，用于处理所接收的信号以确定食品的营养参数。
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公开(公告)号：US20150202333A1
公开(公告)日：2015-07-23
申请号：US14161863
申请日：2014-01-23
Applicant: General Electric Company
Inventor： Bruce Allan Hay , Jack Mathew Webster
CPC classification number: A61K51/0446 , A61K49/0004 , A61K51/0406 , C07B59/002 , G01N33/5091
Abstract: Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection.
Abstract translation: 描述了包含能够通过胱氨酸/谷氨酸反向转运体引入细胞的标记底物的成像剂。 通过将标记的试剂通过胱氨酸/谷氨酸反转录酶引入细胞并随后检测，底物可用于成像或检测细胞中的氧化应激。
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Patent Agency Ranking
公开(公告)号：US09468693B2
公开(公告)日：2016-10-18
申请号：US14161863
申请日：2014-01-23
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Bruce Allan Hay , Jack Mathew Webster
CPC classification number: A61K51/0446 , A61K49/0004 , A61K51/0406 , C07B59/002 , G01N33/5091
Abstract: Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection.
Abstract translation: 描述了包含能够通过胱氨酸/谷氨酸反向转运体引入细胞的标记底物的成像剂。 通过将标记的试剂通过胱氨酸/谷氨酸反转录酶引入细胞并随后检测，底物可用于成像或检测细胞中的氧化应激。
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公开(公告)号：US09468692B2
公开(公告)日：2016-10-18
申请号：US14161809
申请日：2014-01-23
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Bruce Allan Hay , Jack Mathew Webster
IPC: A61K51/00 , A61M36/14 , A61K51/04 , C07C271/22 , C07C311/19 , C07C233/47 , C07C233/51 , C07C233/83 , C07C235/52 , C07B59/00
CPC classification number: A61K51/0406 , C07B59/001 , C07C233/47 , C07C233/51 , C07C233/83 , C07C235/52 , C07C271/22 , C07C311/19
Abstract: Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection.
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公开(公告)号：US20150202332A1
公开(公告)日：2015-07-23
申请号：US14161809
申请日：2014-01-23
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Bruce Allan Hay , Jack Mathew Webster
IPC: A61K51/04 , G01N33/60 , C07C317/50 , C07C237/12 , C07C237/36
CPC classification number: A61K51/0406 , C07B59/001 , C07C233/47 , C07C233/51 , C07C233/83 , C07C235/52 , C07C271/22 , C07C311/19
Abstract: Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection.
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公开(公告)号：US20130071878A1
公开(公告)日：2013-03-21
申请号：US13682497
申请日：2012-11-20
Applicant: General Electric Company
Inventor： Faisal Ahmed Syud , Jack Mathew Webster
IPC: C07K14/00
Abstract: Provided herein are isolated polypeptides derived from the staphylococcal protein A protein B domain comprising a pair of anti-parallel alpha helices that are capable of binding a target. Also provided are nucleic acid sequences encoding such two helix binders, vectors containing the nucleic acid sequences encoding for two helix binders, and host cells transformed with vectors containing the nucleic acid sequences encoding for the two-helix binders. Also provided are methods of using the two helix binders.
Abstract translation: 本文提供了衍生自葡萄球菌蛋白A蛋白B结构域的分离的多肽，其包含能够结合靶标的一对反平行α螺旋。 还提供了编码这种两个螺旋粘合剂的核酸序列，含有编码两个螺旋结合物的核酸序列的载体，以及用含有编码双螺旋结合物的核酸序列的载体转化的宿主细胞。 还提供了使用两种螺旋粘合剂的方法。
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7.发明申请公开(公告)号：US20140331796A1
公开(公告)日：2014-11-13
申请号：US13888759
申请日：2013-05-07
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Yongjae Lee , Aghogho Atemu Obi , Seog Tae Kim , William Chester Platt , James William Bray , Yuri Alexeyevich Plotnikov , Jack Mathew Webster , Vasile Bogdan Neculaes
IPC: G01N33/02
Abstract: A system for measuring nutritional parameters of food items is provided. The system includes a holding cavity. The system further includes a sensor assembly that includes a transmitter antenna and at least one receiver antenna. The transmitter antenna is configured to transmit signals to a food item in the holding cavity. The receiver antenna is configured to receive response signals from the food item. The system includes at least one switch coupled to each antenna. The switch, in a first state, is configured to set the sensor assembly to an electric potential equal to that of the holding cavity. In a second state, the switch is configured to couple the sensor assembly to a power source. The system also includes a processing unit to process the signals received to determine the nutritional parameters of the food item.
Abstract translation: 提供了一种用于测量食品营养参数的系统。 该系统包括一个保持腔。 该系统还包括传感器组件，其包括发射器天线和至少一个接收器天线。 发射机天线被配置为将信号发送到保持腔中的食物。 接收器天线被配置为从食品接收响应信号。 该系统包括耦合到每个天线的至少一个开关。 在第一状态下的开关被配置成将传感器组件设置成等于保持腔的电位。 在第二状态下，开关被配置成将传感器组件耦合到电源。 该系统还包括处理单元，用于处理所接收的信号以确定食品的营养参数。
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