公开(公告)号：US10343971B2

公开(公告)日：2019-07-09

申请号：US16071739

申请日：2017-02-15

Applicant: GIVAUDAN SA

Inventor： Andreas Goeke ,  Felix Flachsmann ,  Dominique Lelievre ,  Andreas Natsch ,  Francis Voirol ,  Yue Zou ,  Thierry Granier

IPC: C07C69/608 ,  C07C229/04 ,  C07C323/52 ,  A61Q13/00 ,  A61K8/37 ,  A61K8/46 ,  C07C69/533 ,  C07C69/56

Abstract: A compound of formula I wherein R1, R2, R3 and R4 can be independently selected from H or Me, n=0, 1, the dotted lines are indicating single bonds, or in case n=0 an isolated double bond at position 3′, or in case n=1 an isolated double bond at position 3′ or 4′, and the wavy bond is indicating an unspecified configuration of the adjacent double bond. Said compounds, as well as precursors capable to generate said compounds, are useful as fragrance ingredients.

公开(公告)号：US08691746B2

公开(公告)日：2014-04-08

申请号：US13647161

申请日：2012-10-08

Applicant: Givaudan SA

Inventor： Andreas Goeke ,  Yue Zou

IPC: C07C47/45 ,  C07C47/445 ,  C07C35/18 ,  C07C35/27

CPC classification number: C07C45/75 ,  A23L27/2024 ,  A23L27/2026 ,  A23L27/2028 ,  A23L27/203 ,  A23L27/2052 ,  C07C33/14 ,  C07C45/292 ,  C07C47/445 ,  C07C47/45 ,  C07C49/553 ,  C07C49/557 ,  C07C251/44 ,  C07C403/02 ,  C07C2601/16 ,  C07C2602/08 ,  C07C2602/10 ,  C11B9/0034 ,  C11B9/0042 ,  C11B9/0049 ,  C11B9/0053 ,  C11B9/0057 ,  C11B9/0076 ,  C11B9/008 ,  C11B9/0088

Abstract: The present invention relates to a process for the production of formyl cyclohexene derivatives which are suitable as odorants as such or as intermediates for the preparation of further odorants. In particular the present invention relates to a domino-methylenation-Diels-Alder reaction of α,β-unsaturated aldehydes using formaldehyde in the presence of 1,3-butadienes.

Abstract translation: 本发明涉及一种生产甲酰基环己烯衍生物的方法，其适合作为气味，或作为制备其它气味剂的中间体。 特别地，本发明涉及在1,3-丁二烯存在下使用甲醛的α，β-不饱和醛的多甲基亚甲基化 - 狄尔斯 - 阿尔德反应。

公开(公告)号：US11020333B2

公开(公告)日：2021-06-01

申请号：US16321653

申请日：2017-08-14

Applicant: Givaudan SA

Inventor： Yue Zou ,  An Chai ,  Jie Liu ,  Lijun Zhou

IPC: A61K8/18 ,  A61Q13/00 ,  A61K8/00 ,  A61K8/35 ,  A61L9/01 ,  C11B9/00 ,  C11D3/50

Abstract: The present invention refers to indanone derivatives of formula (I) wherein R1 is selected from hydrogen, methyl and ethyl; R2 is selected from hydrogen, methyl and ethyl, and R is selected from hydrogen and methyl; or R2 and R3 form together with the carbon atoms to which they are attached C3-C5 cycloalkyl; and R4 is selected from C2-C5 alkyl, C2-C5 alkenyl, C1-C4 alkoxy, C3-C5 cycloalkyl, and C3-C6 cycloalkenyl. The invention further refers to perfume compositions and fragrance applications comprising them.

公开(公告)号：USRE49502E1

公开(公告)日：2023-04-25

申请号：US16922570

申请日：2020-07-07

Applicant: GIVAUDAN SA

Inventor： Corinne Baumgartner ,  Yue Zou

IPC: C11B9/00 ,  C07C47/228 ,  C11D3/50

Abstract: A compound represented by the formula 1 wherein R1 is H, or when R2 and R3 is H, then R1 is CHR5CHR6CHO, CR5═CR6CHO or C(CH3)CHO, wherein R5, R6 each independently may represent H or methyl; R2 is H, or when R1 and R3 is H, then R2 is CHR5CHR6CHO, CR5═CR6CHO or C(CH3)CHO, wherein R5, R6 each independently may represent H or methyl; R3 is H, or when R1 and R2 is H, then R3 is CHR5CHR6CHO, CR5═CR6CHO or C(CH3)CHO, wherein R5, R6 each independently may represent H or methyl; and R4 is methyl or a branched or linear, saturated or unsaturated, unsubstituted or substituted (optionally with cyclopropyl groups), C2-C7 alkyl or alkenyl residue, preferentially isobutyl, isoamyl. Said compounds are useful as perfume ingredients in personal care and household care products.

公开(公告)号：US10443018B2

公开(公告)日：2019-10-15

申请号：US15516810

申请日：2015-10-09

Applicant: GIVAUDAN SA

Inventor： Corinne Baumgartner ,  Yue Zou

IPC: C07C47/00 ,  C11B9/00 ,  C07C47/228 ,  C11D3/50

Abstract: A compound represented by the formula 1 wherein R1 is H, or when R2 and R3 is H, then R1 is CHR5CHR6CHO, CR5═CR6CHO or C(CH3)CHO, wherein R5, R6 each independently may represent H or methyl; R2 is H, or when R1 and R3 is H, then R2 is CHR5CHR6CHO, CR5═CR6CHO or C(CH3)CHO, wherein R5, R6 each independently may represent H or methyl; R3 is H, or when R1 and R2 is H, then R3 is CHR5CHR6CHO, CR5═CR6CHO or C(CH3)CHO, wherein R5, R6 each independently may represent H or methyl; and R4 is methyl or a branched or linear, saturated or unsaturated, unsubstituted or substituted (optionally with cyclopropyl groups), C2-C7 alkyl or alkenyl residue, preferentially isobutyl, isoamyl. Said compounds are useful as perfume ingredients in personal care and household care products.

公开(公告)号：US10400193B2

公开(公告)日：2019-09-03

申请号：US15746320

申请日：2016-07-27

Applicant: GIVAUDAN SA

Inventor： Yue Zou ,  Andreas Goeke ,  Dominique Lelievre ,  Jie Liu

IPC: C11D3/50 ,  C11B9/00 ,  A61K8/34 ,  A61Q5/02 ,  A61Q13/00 ,  C07C33/025

Abstract: 2,4,7-Trimethyloct-6-en-1-ol which is useful as a fragrance ingredient.

公开(公告)号：US20150038386A1

公开(公告)日：2015-02-05

申请号：US14117983

申请日：2012-05-25

Applicant: GIVAUDAN SA

Inventor： Hai-Shan Dang ,  Andreas Goeke ,  Yue Zou

IPC: C11B9/00 ,  A61Q5/02 ,  A61Q19/10 ,  C11D3/50 ,  A61K8/34

CPC classification number: C11B9/003 ,  A61K8/34 ,  A61K2800/10 ,  A61Q5/02 ,  A61Q19/10 ,  C07C33/02 ,  C07C33/05 ,  C07C2601/02 ,  C11B9/0015 ,  C11D3/50

Abstract: Compounds of formula (I) wherein R is hydrogen and the bond between C-2 and C-3 together with the dotted line represents a double bond, or R is —CH2— and together with C-2 and C-3 represents a cyclopropane ring and the bond between C-2 and C-3 together with the dotted line represents a single bond, having floral rosy odor notes, their use as fragrance and perfumed products comprising them.

Abstract translation: 式（I）的化合物，其中R是氢，C-2和C-3之间的键与虚线一起表示双键，或R是-CH 2 - ，并且与C-2和C-3一起代表环丙烷 环和C-2和C-3之间的键与虚线一起表示单键，具有花香玫瑰香味，它们作为香料的用途和包含它们的加香产品。