公开(公告)号：US11773139B2

公开(公告)日：2023-10-03

申请号：US16770963

申请日：2018-12-14

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Stefania Capone ,  Antonella Folgori ,  Armin Lahm ,  Benjamin Wizel

IPC: C07K14/005 ,  A61K39/245 ,  C12N7/00 ,  A61K39/00

CPC classification number: C07K14/005 ,  A61K39/245 ,  C12N7/00 ,  A61K2039/70 ,  C12N2710/16222 ,  C12N2710/16234 ,  C12N2710/16271

Abstract: The invention provides Epstein-Barr Virus antigen polynucleotides, polypeptides and vectors; as well as immunogenic compositions comprising the same. It includes the use of Epstein-Barr Virus antigen constructs to produce vaccines for treating and preventing Epstein-Barr Virus infections and Epstein-Barr Virus-associated diseases, such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus.

公开(公告)号：US12264179B2

公开(公告)日：2025-04-01

申请号：US18358350

申请日：2023-07-25

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Stefania Capone ,  Antonella Folgori ,  Armin Lahm ,  Benjamin Wizel

IPC: C07K14/005 ,  A61K39/00 ,  A61K39/245 ,  C12N7/00

Abstract: The invention provides Epstein-Barr Virus antigen polynucleotides, polypeptides and vectors; as well as immunogenic compositions comprising the same. It includes the use of Epstein-Barr Virus antigen constructs to produce vaccines for treating and preventing Epstein-Barr Virus infections and Epstein-Barr Virus-associated diseases, such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus.