公开(公告)号：US11649467B2

公开(公告)日：2023-05-16

申请号：US16631557

申请日：2018-07-19

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Benjamin Wizel ,  Martine Harvey ,  Lucile Warter ,  Kate Luisi

IPC: C12N15/86 ,  A61K39/12

CPC classification number: C12N15/86 ,  A61K39/12 ,  C12N2710/10343 ,  C12N2770/36123 ,  C12N2770/36134

Abstract: The invention provides adenoviral vectors comprising transgenes encoding Chikungunya virus antigens. The vectors can be used to produce vaccines for the prophylaxis, amelioration and treatment of diseases caused by Chikungunya virus infections.

公开(公告)号：US11773139B2

公开(公告)日：2023-10-03

申请号：US16770963

申请日：2018-12-14

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Stefania Capone ,  Antonella Folgori ,  Armin Lahm ,  Benjamin Wizel

IPC: C07K14/005 ,  A61K39/245 ,  C12N7/00 ,  A61K39/00

CPC classification number: C07K14/005 ,  A61K39/245 ,  C12N7/00 ,  A61K2039/70 ,  C12N2710/16222 ,  C12N2710/16234 ,  C12N2710/16271

Abstract: The invention provides Epstein-Barr Virus antigen polynucleotides, polypeptides and vectors; as well as immunogenic compositions comprising the same. It includes the use of Epstein-Barr Virus antigen constructs to produce vaccines for treating and preventing Epstein-Barr Virus infections and Epstein-Barr Virus-associated diseases, such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus.

公开(公告)号：US12264179B2

公开(公告)日：2025-04-01

申请号：US18358350

申请日：2023-07-25

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Stefania Capone ,  Antonella Folgori ,  Armin Lahm ,  Benjamin Wizel

IPC: C07K14/005 ,  A61K39/00 ,  A61K39/245 ,  C12N7/00

Abstract: The invention provides Epstein-Barr Virus antigen polynucleotides, polypeptides and vectors; as well as immunogenic compositions comprising the same. It includes the use of Epstein-Barr Virus antigen constructs to produce vaccines for treating and preventing Epstein-Barr Virus infections and Epstein-Barr Virus-associated diseases, such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus.