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公开(公告)号：US11339367B2
公开(公告)日：2022-05-24
申请号：US15094077
申请日：2016-04-08
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Christiane Gerke , Francesco Berlanda Scorza , Allan Saul , Luana Maggiore
Abstract: Hyperblebbing Shigella strains are generated by disrupting one or more components of the Tol-Pal system. The blebs from these strains are useful immunogens for vaccination. The individual proteins found in these blebs can also be used as immunogens.
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