公开(公告)号：US09909135B2

公开(公告)日：2018-03-06

申请号：US13808530

申请日：2011-07-06

申请人： Gad Galili ,  Asaph Aharoni ,  Vered Tzin ,  Sergey Malitsky ,  Ilana Rogachev

发明人： Gad Galili ,  Asaph Aharoni ,  Vered Tzin ,  Sergey Malitsky ,  Ilana Rogachev

IPC分类号： C12N15/82 ,  C12N9/02 ,  A01H5/10 ,  C12N9/88 ,  C12N9/10

CPC分类号： C12N15/8251 ,  C12N9/1085 ,  C12N9/88 ,  C12N15/8243 ,  C12N15/8254 ,  C12N15/8255 ,  C12Y205/01054

摘要： The present invention provides transgenic plants comprising 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate (DAHP) Synthase that is insensitive to feedback inhibition, particularly to feedback inhibition by phenylalanine, producing increased amounts of the Shikimate pathway primary and secondary metabolites, including aromatic amino acids compared to corresponding non-transgenic plants.

公开(公告)号：US20130111631A1

公开(公告)日：2013-05-02

申请号：US13808530

申请日：2011-07-06

申请人： Gad Galili ,  Asaph Aharoni ,  Vered Tzin ,  Sergey Malitsky ,  Ilana Rogachev

发明人： Gad Galili ,  Asaph Aharoni ,  Vered Tzin ,  Sergey Malitsky ,  Ilana Rogachev

IPC分类号： C12N15/82

CPC分类号： C12N15/8251 ,  C12N9/1085 ,  C12N9/88 ,  C12N15/8243 ,  C12N15/8254 ,  C12N15/8255 ,  C12Y205/01054

摘要： The present invention provides transgenic plants comprising 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate (DAHP) Synthase that is insensitive to feedback inhibition, particularly to feedback inhibition by phenylalanine, producing increased amounts of the Shikimate pathway primary and secondary metabolites, including aromatic amino acids compared to corresponding non-transgenic plants.

摘要翻译： 本发明提供了包含对反馈抑制不敏感的3-脱氧-D-阿拉伯 - 七肽 - 七磷酸酯（DAHP）合成酶的转基因植物，特别是苯丙氨酸的反馈抑制，产生增加量的莽草酸通道初级和次级代谢物，包括 芳香族氨基酸与相应的非转基因植物相比。

公开(公告)号：US20100281567A1

公开(公告)日：2010-11-04

申请号：US12745853

申请日：2008-12-03

申请人： Gad Galili ,  Vered Tzin ,  Asaph Aharoni ,  Sergey Malitsky

发明人： Gad Galili ,  Vered Tzin ,  Asaph Aharoni ,  Sergey Malitsky

IPC分类号： A01H1/00 ,  C12N5/10 ,  A01H5/00

CPC分类号： C12N15/8243 ,  C12N15/8251 ,  C12N15/8254

摘要： The present invention relates to means and methods for altering the level of at least one of the aromatic amino acids phenylalanine, tryptophan and tyrosine and secondary metabolites in plants. Particularly, the present invention discloses transgenic plants comprising polynucleotides encoding chorismate mutase and prephenate dehydratase enzymes, having elevated amounts of at least one of phenylalanine, tyrosine and modified amount of at least one secondary metabolite derived therefrom, and reduced amount of tryptophan and at least one secondary metabolite derived from tryptophan.

摘要翻译： 本发明涉及用于改变植物中至少一种芳香族氨基酸苯丙氨酸，色氨酸和酪氨酸和次级代谢物的水平的方法和方法。 特别地，本发明公开了转基因植物，其包含编码绒毛酸变位酶和预沉酸脱水酶的多核苷酸，其具有升高量的苯丙氨酸，酪氨酸和修饰量的至少一种由其衍生的至少一种次级代谢物，并且减少量的色氨酸和至少一种 衍生自色氨酸的次生代谢产物。