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    TRANSGENIC PLANTS HAVING ALTERED LEVELS OF AROMATIC AMINO ACIDS AND METABOLITES DERIVED THEREFROM
    1.
    发明申请
    TRANSGENIC PLANTS HAVING ALTERED LEVELS OF AROMATIC AMINO ACIDS AND METABOLITES DERIVED THEREFROM 审中-公开
    具有改变水平的芳族氨基酸的转基因植物和衍生自其的代谢物

    公开(公告)号：US20100281567A1

    公开(公告)日：2010-11-04

    申请号：US12745853

    申请日：2008-12-03

    申请人： Gad Galili ,  Vered Tzin ,  Asaph Aharoni ,  Sergey Malitsky

    发明人： Gad Galili ,  Vered Tzin ,  Asaph Aharoni ,  Sergey Malitsky

    IPC分类号： A01H1/00 ,  C12N5/10 ,  A01H5/00

    CPC分类号： C12N15/8243 ,  C12N15/8251 ,  C12N15/8254

    摘要： The present invention relates to means and methods for altering the level of at least one of the aromatic amino acids phenylalanine, tryptophan and tyrosine and secondary metabolites in plants. Particularly, the present invention discloses transgenic plants comprising polynucleotides encoding chorismate mutase and prephenate dehydratase enzymes, having elevated amounts of at least one of phenylalanine, tyrosine and modified amount of at least one secondary metabolite derived therefrom, and reduced amount of tryptophan and at least one secondary metabolite derived from tryptophan.

    摘要翻译： 本发明涉及用于改变植物中至少一种芳香族氨基酸苯丙氨酸，色氨酸和酪氨酸和次级代谢物的水平的方法和方法。 特别地，本发明公开了转基因植物，其包含编码绒毛酸变位酶和预沉酸脱水酶的多核苷酸，其具有升高量的苯丙氨酸，酪氨酸和修饰量的至少一种由其衍生的至少一种次级代谢物，并且减少量的色氨酸和至少一种 衍生自色氨酸的次生代谢产物。

    Isoprenoid synthases
    4.
    发明授权
    Isoprenoid synthases 有权
    异戊二烯合酶

    公开(公告)号：US08338663B2

    公开(公告)日：2012-12-25

    申请号：US12272329

    申请日：2008-11-17

    申请人： Asaph Aharoni ,  Maarten Anthonie Jongsma ,  Henricus Adrianus Verhoeven ,  Hendrik Jan Bouwmeester

    发明人： Asaph Aharoni ,  Maarten Anthonie Jongsma ,  Henricus Adrianus Verhoeven ,  Hendrik Jan Bouwmeester

    IPC分类号： A01H5/00 ,  C12N15/29 ,  C12N15/52 ,  C12N15/82

    CPC分类号： C12N15/8282 ,  C12N9/1085 ,  C12N15/8243 ,  C12N15/8286 ,  Y02A40/162

    摘要： The invention relates to the field of genetic engineering of flavor, fragrance and biocontrol agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.

    摘要翻译： 本发明涉及风味，香精和生物防治剂开发的遗传工程领域。 更具体地说，本发明涉及通过控制与该方法相关的一种或多种基因来生产天然香料，香料或生物控制剂的方法。 本发明提供了在合适的反应条件下提供合适的底物时，编码蛋白质分子的分离或重组的核酸或功能片段，其基本上能够进行风味，香料和/或生物控制剂的合成。 本发明进一步提供编码蛋白质分子的核酸或功能片段，当与法呢基二磷酸酯（FPP）接触时，本发明的蛋白质分子在与二香草素二磷酸酯（GPP）和/或至少一种倍半萜烯醇橙花瓶酯接触时基本能够合成至少一种单萜醇里哪醇 在适当的反应条件下。

    Isoprenoid synthases
    5.
    发明授权
    Isoprenoid synthases 有权
    异戊二烯合酶

    公开(公告)号：US07453024B2

    公开(公告)日：2008-11-18

    申请号：US10635223

    申请日：2003-08-05

    申请人： Asaph Aharoni ,  Maarten Anthonie Jongsma ,  Henricus Adrianus Verhoeven ,  Hendrik Jan Bouwmeester

    发明人： Asaph Aharoni ,  Maarten Anthonie Jongsma ,  Henricus Adrianus Verhoeven ,  Hendrik Jan Bouwmeester

    IPC分类号： C12N15/29 ,  C12N15/52 ,  C12N15/82 ,  A01H5/00

    CPC分类号： C12N15/8282 ,  C12N9/1085 ,  C12N15/8243 ,  C12N15/8286 ,  Y02A40/162

    摘要： The invention relates to the field of genetic engineering of flavor, fragrance and bio-control agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.

    摘要翻译： 本发明涉及风味，香精和生物防治剂开发基因工程领域。 更具体地说，本发明涉及通过控制与该方法相关的一种或多种基因来生产天然香料，香料或生物控制剂的方法。 本发明提供了在合适的反应条件下提供合适的底物时，编码蛋白质分子的分离或重组的核酸或功能片段，其基本上能够进行风味，香料和/或生物控制剂的合成。 本发明进一步提供编码蛋白质分子的核酸或功能片段，当与法呢基二磷酸酯（FPP）接触时，本发明的蛋白质分子在与二香草素二磷酸酯（GPP）和/或至少一种倍半萜烯醇橙花瓶酯接触时基本能够合成至少一种单萜醇里哪醇 在适当的反应条件下。

    Transgenic Plant Having Enhanced Drought Tolerance
    8.
    发明申请
    Transgenic Plant Having Enhanced Drought Tolerance 有权
    具有增强耐旱性的转基因植物

    公开(公告)号：US20110209247A1

    公开(公告)日：2011-08-25

    申请号：US11991724

    申请日：2005-09-06

    申请人： Asaph Aharoni ,  Shital Dixit ,  Kurniawan Rudi Trijatmiko ,  Jelle Hiemstra ,  Andy Pereira

    发明人： Asaph Aharoni ,  Shital Dixit ,  Kurniawan Rudi Trijatmiko ,  Jelle Hiemstra ,  Andy Pereira

    IPC分类号： A01H5/00 ,  A01H5/08 ,  A01H5/10 ,  C12N15/82

    CPC分类号： C12N15/8273 ,  C07K14/415 ,  C12N15/8261 ,  C12N15/827 ,  C12N15/8279 ,  C12N15/8282 ,  Y02A40/146

    摘要： The present invention relates to the field of transgenic plants with novel phenotypes, especially plants with enhanced drought and pathogen resistance. Provided are transgenic crop plants comprising integrated in their genome a chimeric gene, characterized by said chimeric gene comprising a transcription regulatory sequence active in plant cells operably linked to a nucleic acid sequence encoding a protein having the sequence of SEQ ID NO: 3 or a protein at least 70% identical to SEQ ID NO: 3, or an ortholog protein or a functional fragment thereof. In addition to enhanced drought tolerance the transgenic plants may show enhanced disease resistance and enhanced root structure.

    摘要翻译： 本发明涉及具有新表型的转基因植物领域，特别是具有增强的干旱和病原体抗性的植物。 提供了包含在其基因组中整合嵌合基因的转基因作物植物，其特征在于所述嵌合基因包含在植物细胞中活性的转录调控序列，其与编码具有SEQ ID NO：3的序列的蛋白质的核酸序列或蛋白质 与SEQ ID NO：3至少70％相同，或直系同源蛋白或其功能片段。 除了增强抗旱能力外，转基因植物可以显示增强的抗病性和增强的根结构。

    Plant transformed with hardy (HRD) gene having enhanced drought tolerance
    9.
    发明授权
    Plant transformed with hardy (HRD) gene having enhanced drought tolerance 有权
    植物用具有增强的耐旱性的强硬（HRD）基因转化

    公开(公告)号：US08940961B2

    公开(公告)日：2015-01-27

    申请号：US11991724

    申请日：2005-09-06

    申请人： Asaph Aharoni ,  Shital Dixit ,  Kurniawan Rudi Trijatmiko ,  Jelle Hiemstra ,  Andy Pereira

    发明人： Asaph Aharoni ,  Shital Dixit ,  Kurniawan Rudi Trijatmiko ,  Jelle Hiemstra ,  Andy Pereira

    IPC分类号： C12N15/29 ,  C12N15/82 ,  C07K14/415

    CPC分类号： C12N15/8273 ,  C07K14/415 ,  C12N15/8261 ,  C12N15/827 ,  C12N15/8279 ,  C12N15/8282 ,  Y02A40/146

    摘要： Transgenic plants with novel phenotypes, especially plants with enhanced drought and pathogen resistance. Provided are transgenic crop plants having integrated in their genome a chimeric gene, wherein the chimeric gene includes a transcription regulatory sequence active in plant cells operably linked to a nucleic acid sequence encoding a protein having the sequence of SEQ ID NO: 3 or a protein at least 70% identical to SEQ ID NO: 3 or an ortholog or a functional fragment thereof. In addition to enhanced drought tolerance the transgenic plants may show enhanced disease resistance and enhanced root structure. Also, a method for generating a transgenic plant by insertion of the chimeric gene.

    摘要翻译： 具有新型表型的转基因植物，特别是具有增强的干旱和病原体抗性的植物。 提供了在其基因组中整合了嵌合基因的转基因作物植物，其中嵌合基因包括在编码具有SEQ ID NO：3的序列的蛋白质的核酸序列的有效连接的植物细胞中的转录调控序列或蛋白质 与SEQ ID NO：3至少70％相同或直向同源物或其功能片段。 除了增强抗旱能力外，转基因植物可以显示增强的抗病性和增强的根结构。 另外，通过插入嵌合基因产生转基因植物的方法。