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公开(公告)号:US20100310658A1
公开(公告)日:2010-12-09
申请号:US12796207
申请日:2010-06-08
IPC分类号: A61K9/00 , C07K14/435 , A61K38/36 , A61K35/00 , A61K38/18 , A61K35/12 , C12Q1/02 , A61P17/02 , A61P7/00 , C25D9/02
CPC分类号: C12N5/0622 , A61K35/12 , A61K2035/126 , A61L15/32 , A61L27/225 , A61L27/24 , A61L27/26 , A61L27/38 , A61L31/041 , A61L2400/04 , B29C41/006 , C07K14/75 , C07K14/78 , C12N5/0012 , C12N5/0062 , C12N5/0068 , C12N2503/00 , C12N2510/00 , C12N2533/40 , C12N2533/54 , C12N2533/56 , C08L89/00
摘要: The invention is directed to formation and use of electroprocessed fibrin as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed fibrin may also be combined with other molecules in order to deliver the molecules to the site of application or implantation of the electroprocessed fibrin. The fibrin or fibrin/cell suspension is electrodeposited onto a substrite to form the tissues and organs.
摘要翻译: 本发明涉及形成和使用电加工的纤维蛋白作为细胞外基质,并与细胞一起用于形成工程化组织。 工程组织可以包括可以植入受体的特定器官或组织的合成制造。 电加工的纤维蛋白也可以与其它分子组合以将分子递送到电加工的纤维蛋白的施用位点或植入。 将纤维蛋白或纤维蛋白/细胞悬浮液电沉积到一个亚晶体上以形成组织和器官。
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公开(公告)号:US20100291058A1
公开(公告)日:2010-11-18
申请号:US12758360
申请日:2010-04-12
申请人: Gary L. Bowlin , David G. Simpson , Gary E. Wnek , Marcus E. Carr, JR. , Peter J. Stevens , Gary Cadd , I. Kelman Cohen
发明人: Gary L. Bowlin , David G. Simpson , Gary E. Wnek , Marcus E. Carr, JR. , Peter J. Stevens , Gary Cadd , I. Kelman Cohen
CPC分类号: A61L24/102 , A61F2/105 , A61F2013/00314 , A61F2013/00472 , A61K38/363 , A61K38/39 , A61L24/106 , C07K14/78 , Y10T428/298 , A61K2300/00
摘要: The present invention relates to sealants for skin and other tissues. The sealants include an electroprocessed material. The sealants may contain more than one electroprocessed materials and may contain additional substances. The invention further relates to methods of making and using such sealants.
摘要翻译: 本发明涉及用于皮肤和其它组织的密封剂。 密封剂包括电加工材料。 密封剂可能含有多于一种的电处理材料,并且可能含有其他物质。 本发明还涉及制造和使用这种密封剂的方法。
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