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公开(公告)号：US11118237B2
公开(公告)日：2021-09-14
申请号：US16212539
申请日：2018-12-06
Applicant: GEN-PROBE INCORPORATED
Inventor： Reinhold B. Pollner , Shyun-Shyun Lee
IPC: C12Q1/70
Abstract: Disclosed are nucleic acid oligomers for amplifying one or more selected regions of HCV nucleic acid. Also disclosed are methods for specific amplification and characterization of HCV nucleic acid using the disclosed oligomers, as well as corresponding reaction mixtures and kits.
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公开(公告)号：US09914982B2
公开(公告)日：2018-03-13
申请号：US14827087
申请日：2015-08-14
Applicant: Gen-Probe Incorporated
Inventor： Jeffrey M. Linnen , Daniel P. Kolk , Janel M. Dockter , Damon K. Getman , Tadashi Yoshimura , Martha K. Ho-Sing-Loy , Reinhold B. Pollner , Leslie A. Stringfellow
Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.
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3.发明申请COMPOSITIONS AND METHODS FOR AMPLIFYING AND CHARACTERIZING HCV NUCLEIC ACID 审中-公开用于放大和表征HCV核酸的组合物和方法公开(公告)号：US20150152513A1
公开(公告)日：2015-06-04
申请号：US14405765
申请日：2013-06-03
Applicant: Gen-Probe Incorporated
Inventor： Reinhold B. Pollner , Shyun-Shyun Lee
IPC: C12Q1/70
CPC classification number: C12Q1/707 , C12Q2531/113 , C12Q2600/156 , C12Q2600/16
Abstract: Disclosed are nucleic acid oligomers for amplifying one or more selected regions of HCV nucleic acid. Also disclosed are methods for specific amplification and characterization of HCV nucleic acid using the disclosed oligomers, as well as corresponding reaction mixtures and kits.
Abstract translation: 公开了用于扩增HCV核酸的一个或多个选择区域的核酸低聚物。 还公开了使用所公开的寡聚体以及相应的反应混合物和试剂盒来特异性扩增和表征HCV核酸的方法。
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公开(公告)号：US10781495B2
公开(公告)日：2020-09-22
申请号：US15411448
申请日：2017-01-20
Applicant: GEN-PROBE INCORPORATED
Inventor： Jeffrey M. Linnen , Reinhold B. Pollner
IPC: C12Q1/6818 , C12Q1/6816 , C07H21/04 , C12Q1/70
Abstract: Compositions for detecting flavivirus nucleic acids. Particularly described are compositions for detecting West Nile virus nucleic acids in the 3′ non-coding region. These compositions are preferably oligonucleotides comprising nucleotide sequences that are substantially complementary to a West Nile virus target nucleic acid. These compositions preferably comprise a detectable moiety.
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5.发明授权公开(公告)号：US09580762B2
公开(公告)日：2017-02-28
申请号：US14273835
申请日：2014-05-09
Applicant: GEN-PROBE INCORPORATED
Inventor： Jeffrey M. Linnen , Reinhold B. Pollner
CPC classification number: C12Q1/701 , C12Q1/6816 , C12Q1/6818
Abstract: Methods for detecting flavivirus nucleic acids. Particularly described are methods for detecting West Nile virus nucleic acids in the 3′ non-coding region.
Abstract translation: 检测黄病毒核酸的方法。 特别描述了用于检测3'非编码区中的西尼罗河病毒核酸的方法。
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Patent Agency Ranking
6.发明申请COMPOSITIONS AND METHODS TO DETECT LEGIONELLA PNEUMOPHILA NUCLEIC ACID 有权组合物和检测LEGIONELLA PNEUMOPHILA核酸的方法公开(公告)号：US20140113289A1
公开(公告)日：2014-04-24
申请号：US14075944
申请日：2013-11-08
Applicant: Gen-Probe Incorporated
Inventor： Jennifer J. Bungo , James J. Hogan , Reinhold B. Pollner , Marie K. Hudspeth , Shannon K. Kaplan , Elizabeth M. Marlowe
IPC: C12Q1/68
CPC classification number: C12Q1/689 , C12Q1/686 , Y02A50/451
Abstract: Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, and detection probes that hybridize specifically to Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Methods are disclosed for amplifying and/or detecting the presence of L. pnuemophila in samples by using the disclosed compositions in in vitro methods that include nucleic acid amplification and/or detection of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA.
Abstract translation: 公开了组合物作为可用作扩增寡聚物的核酸序列，包括引物和与嗜肺军团菌23S rRNA序列或编码23S rRNA的DNA特异性杂交的检测探针。 公开了含有用于体外扩增和/或检测嗜肺军团菌23S rRNA序列或编码23S rRNA的DNA的寡核苷酸的反应混合物。 公开了用于通过使用所公开的组合物在体外方法中扩增和/或检测样品中存在嗜血杆菌的方法，其包括核酸扩增和/或检测23S rRNA序列或编码23S rRNA序列的DNA以产生 可检测扩增产物。 公开了含有用于体外扩增和/或检测嗜肺军团菌23S rRNA序列或编码23S rRNA的DNA的寡核苷酸的反应混合物。
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公开(公告)号：US10745767B2
公开(公告)日：2020-08-18
申请号：US15879921
申请日：2018-01-25
Applicant: GEN-PROBE INCORPORATED
Inventor： Jeffrey M. Linnen , Daniel P. Kolk , Janel M. Dockter , Damon K. Getman , Tadashi Yoshimura , Martha K. Ho-Sing-Loy , Reinhold B. Pollner , Leslie A. Stringfellow
Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.
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公开(公告)号：US20190093183A1
公开(公告)日：2019-03-28
申请号：US16212539
申请日：2018-12-06
Applicant: GEN-PROBE INCORPORATED
Inventor： Reinhold B. Pollner , Shyun-Shyun Lee
IPC: C12Q1/70
Abstract: Disclosed are nucleic acid oligomers for amplifying one or more selected regions of HCV nucleic acid. Also disclosed are methods for specific amplification and characterization of HCV nucleic acid using the disclosed oligomers, as well as corresponding reaction mixtures and kits.
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公开(公告)号：US10190180B2
公开(公告)日：2019-01-29
申请号：US14405765
申请日：2013-06-03
Applicant: Gen-Probe Incorporated
Inventor： Reinhold B. Pollner , Shyun-Shyun Lee
IPC: C12Q1/70
Abstract: Disclosed are nucleic acid oligomers for amplifying one or more selected regions of HCV nucleic acid. Also disclosed are methods for specific amplification and characterization of HCV nucleic acid using the disclosed oligomers, as well as corresponding reaction mixtures and kits.
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公开(公告)号：US09845509B2
公开(公告)日：2017-12-19
申请号：US14075944
申请日：2013-11-08
Applicant: Gen-Probe Incorporated
Inventor： Jennifer J. Bungo , James J. Hogan , Reinhold B. Pollner , Marie K. Hudspeth , Shannon K. Kaplan , Elizabeth M. Marlowe
IPC: C12Q1/68
CPC classification number: C12Q1/689 , C12Q1/686 , Y02A50/451
Abstract: Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, and detection probes that hybridize specifically to Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Methods are disclosed for amplifying and/or detecting the presence of L. pnuemophila in samples by using the disclosed compositions in in vitro methods that include nucleic acid amplification and/or detection of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA.
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