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公开(公告)号:US09937224B2
公开(公告)日:2018-04-10
申请号:US14822711
申请日:2015-08-10
Applicant: Genentech, Inc.
Inventor: Ryan J. Watts , Mark Chen , Joseph Wesley Lewcock , Christine Pozniak , Arundhati Sengupta-Ghosh
IPC: A61K39/395 , A61K33/14 , A61K31/40 , A61K38/12 , A61K31/7088 , A61K31/711 , C12N15/113 , A61K31/7105 , A61K31/277 , A61K31/35 , A61K31/4015 , A61K31/416 , A61K31/4439 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K38/05 , A61K38/18 , C07K16/22 , G01N33/50 , A61K31/12 , A61K31/165 , A61K31/352 , A61K31/4184 , A61K31/426 , A61K31/433 , A61K31/45 , A61K31/496 , A61K31/505 , A61K31/517 , A61K31/519 , A61K31/713 , C07K16/40
CPC classification number: A61K38/12 , A61K31/12 , A61K31/165 , A61K31/277 , A61K31/35 , A61K31/352 , A61K31/40 , A61K31/4015 , A61K31/416 , A61K31/4184 , A61K31/426 , A61K31/433 , A61K31/4439 , A61K31/45 , A61K31/496 , A61K31/505 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K31/7088 , A61K31/7105 , A61K31/711 , A61K31/713 , A61K33/14 , A61K38/05 , A61K38/185 , C07K16/22 , C07K16/40 , C07K2317/76 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2320/30 , G01N33/5058
Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
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公开(公告)号:US20140328940A1
公开(公告)日:2014-11-06
申请号:US14136379
申请日:2013-12-20
Applicant: Genentech, Inc.
Inventor: Joseph W. LEWCOCK , Christine Pozniak , Arundhati Sengupta-Ghosh
IPC: A61K35/30 , A61K39/395 , A61K31/715 , A61K31/7088 , C12N15/115 , A61K38/00 , C07K16/40 , C12N15/113
CPC classification number: A61K38/45 , A61K31/7088 , A61K31/7105 , A61K31/715 , A61K35/30 , A61K38/005 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/54 , C07K16/40 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C12N15/1137 , C12N15/115 , C12N2310/11 , C12N2310/14 , C12N2310/16 , C12Y207/11025 , A61K2300/00
Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
Abstract translation: 本发明一般涉及治疗神经系统疾病和神经系统损伤。 本发明具体提供了使用特定靶蛋白的调节剂调节神经元或其部分如轴突的变性的方法。
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