公开(公告)号：US12037385B2

公开(公告)日：2024-07-16

申请号：US17346534

申请日：2021-06-14

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Robert F. Kelley ,  Marissa L. Matsumoto

IPC: G01N33/53 ,  C07K14/47 ,  C07K16/18 ,  C12N15/10 ,  G01N33/68

CPC classification number: C07K16/18 ,  C07K14/4702 ,  C12N15/1037 ,  G01N33/68 ,  C07K2317/24 ,  C07K2317/30 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/92 ,  G01N2333/4703 ,  G01N2440/36

Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.

公开(公告)号：US10738106B2

公开(公告)日：2020-08-11

申请号：US15071422

申请日：2016-03-16

Applicant: Genentech, Inc.

Inventor： Robert F. Kelley ,  Vishva Dixit ,  Marissa L. Matsumoto

IPC: C07K16/18 ,  G01N33/68 ,  C07K16/40

Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.

公开(公告)号：US20190169278A1

公开(公告)日：2019-06-06

申请号：US16211669

申请日：2018-12-06

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Marissa Matsumoto ,  Erick Castellanos

IPC: C07K16/18 ,  C12N15/62 ,  G01N33/68 ,  A61K47/68

Abstract: The invention provides antibodies having greater avidity for a mixed-topology polyubiquitin than a single-topology polyubiquitin and multispecific anti-polyubiquitin antibodies, and methods of using the same.

公开(公告)号：US09556262B2

公开(公告)日：2017-01-31

申请号：US14627597

申请日：2015-02-20

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Robert F. Kelley ,  Marissa L. Matsumoto

IPC: G01N33/53 ,  C07K16/18 ,  C07K14/47 ,  G01N33/68

CPC classification number: C07K16/18 ,  C07K14/4702 ,  C07K2317/24 ,  C07K2317/30 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/92 ,  C12N15/1037 ,  G01N33/68 ,  G01N2333/4703 ,  G01N2440/36

Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.

Abstract translation: 本发明提供抗多聚遍在蛋白抗体及其使用方法。

公开(公告)号：US12215143B2

公开(公告)日：2025-02-04

申请号：US17576344

申请日：2022-01-14

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Marissa Matsumoto ,  Erick Castellanos

IPC: C07K16/18 ,  C12N15/62 ,  G01N33/68

Abstract: The invention provides antibodies that bind mixed-topology polyubiquitin and multispecific anti-polyubiquitin antibodies, and methods of using the same.

公开(公告)号：US11066463B2

公开(公告)日：2021-07-20

申请号：US16131608

申请日：2018-09-14

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Robert F. Kelley ,  Marissa L. Matsumoto

IPC: G01N33/53 ,  C07K16/18 ,  C07K14/47 ,  G01N33/68 ,  C12N15/10

Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.

公开(公告)号：US20190100578A1

公开(公告)日：2019-04-04

申请号：US16131608

申请日：2018-09-14

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Robert F. Kelley ,  Marissa L. Matsumoto

IPC: C07K16/18 ,  G01N33/68 ,  C07K14/47 ,  C12N15/10

Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.

公开(公告)号：US10100105B2

公开(公告)日：2018-10-16

申请号：US15381452

申请日：2016-12-16

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Robert F. Kelley ,  Marissa L. Matsumoto

IPC: C07K16/00 ,  C07K16/18 ,  C12N15/10

Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.

公开(公告)号：US12286470B2

公开(公告)日：2025-04-29

申请号：US18159728

申请日：2023-01-26

Applicant: Genentech, Inc.

Inventor： Robert F. Kelley ,  Vishva Dixit ,  Marissa L. Matsumoto

IPC: C07K16/18 ,  C07K16/40 ,  G01N33/68

Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.

公开(公告)号：US20250122272A1

公开(公告)日：2025-04-17

申请号：US18983995

申请日：2024-12-17

Applicant: Genentech, Inc.

Inventor： Vishva Dixit ,  Marissa Matsumoto ,  Erick Castellanos

IPC: C07K16/18 ,  C12N15/62 ,  G01N33/68

Abstract: The invention provides antibodies that bind mixed-topology polyubiquitin and multispecific anti-polyubiquitin antibodies, and methods of using the same.