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公开(公告)号：US20240052392A1
公开(公告)日：2024-02-15
申请号：US18491555
申请日：2023-10-20
Applicant: GENENTECH, INC.
Inventor： Steven J. Meier , Melissa S. Mun , Natarajan Vijayasankaran , Sharat Varma , Yi Yang , Boyan Zhang , Silvana R. Arevalo , Martin Gawlitzek , Veronica Carvalhal
CPC classification number: C12P21/00 , C12N5/005 , C07K16/2839 , C07K16/00 , C12N2500/38 , C12N2500/32 , C07K2317/14 , C12N2511/00 , C12N2500/24 , C12N2501/39
Abstract: Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided.
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公开(公告)号：US20150267237A1
公开(公告)日：2015-09-24
申请号：US14396609
申请日：2013-04-24
Applicant: Genentech, Inc.
Inventor： Steven J. Meier , Melissa S. Mun , Natarajan Vijayasankaran , Sharat Varma , Yi Yang , Boyan Zhang , Silvana R. Arevalo , Martin Gawlitzek , Veronica Carvalhal
CPC classification number: C12P21/00 , C07K16/00 , C07K16/2839 , C07K2317/14 , C12N5/005 , C12N2500/24 , C12N2500/32 , C12N2500/38 , C12N2501/39 , C12N2511/00
Abstract: Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided.
Abstract translation: 提供细胞培养基，例如化学确定的细胞培养基，以及使用培养基用于细胞生长（即细胞培养）和多肽（例如抗体）生产的方法。 还提供了包含通过该方法生产的多肽的组合物。
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公开(公告)号：US20240093143A1
公开(公告)日：2024-03-21
申请号：US18497162
申请日：2023-10-30
Applicant: GENENTECH, INC.
Inventor： Natarajan Vijayasankaran , Steven J. Meier , Melissa S. Mun , Sharat Varma , Yi Yang , Boyan Zhang , Silvana R. Arevalo , Martin Gawlitzek , Veronica Carvalhal
CPC classification number: C12N5/0018 , C07K16/00 , C12N5/005 , C12P21/00 , C12N2500/24 , C12N2500/32 , C12N2500/38 , C12N2501/39
Abstract: Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided.
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公开(公告)号：US11371999B2
公开(公告)日：2022-06-28
申请号：US16195409
申请日：2018-11-19
Applicant: Genentech, Inc. , University of Kansas
Inventor： Anna Mah , Christian Schoeneich , Yi Yang , Di Gao , Lynn A. Gennaro
IPC: G01N33/68 , G01N33/58 , G01N33/50 , G01N33/533
Abstract: The description relates to a method and kits for determining the total carbonylation level on a polypeptide.
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公开(公告)号：US20190219590A1
公开(公告)日：2019-07-18
申请号：US16195409
申请日：2018-11-19
Applicant: Genentech, Inc. , University of Kansas
Inventor： Anna Mah , Christian Schoeneich , Yi Yang , Di Gao , Lynn A. Gennaro
CPC classification number: G01N33/6842 , G01N33/502 , G01N33/533 , G01N33/582 , G01N2440/00
Abstract: The description relates to a method and kits for determining the total carbonylation level on a polypeptide.
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Patent Agency Ranking
6.发明公开公开(公告)号：US20230314389A1
公开(公告)日：2023-10-05
申请号：US18206853
申请日：2023-06-07
Applicant: GENENTECH, INC.
Inventor： Yi Yang
IPC: G01N30/72
CPC classification number: G01N30/7266
Abstract: The present disclosure relates to methods and compositions for determining the relative distribution of glucuronidation, iduronidation, and/or galacturonidation of polypeptides, including stereoselective liquid chromatography-mass spectrometry (LC-MS) methods capable of achieving the simultaneous separation and relative quantitation of glucuronidation, iduronidation, and/or galacturonidation of polypeptides.
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公开(公告)号：US10131873B2
公开(公告)日：2018-11-20
申请号：US14852311
申请日：2015-09-11
Applicant: Genentech, Inc.
Inventor： Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号：US10017732B2
公开(公告)日：2018-07-10
申请号：US14211416
申请日：2014-03-14
Applicant: Genentech, Inc.
Inventor： Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
CPC classification number: C12N5/0018 , C07K16/00 , C07K2317/14 , C12N2500/30 , C12N2500/33 , C12N2500/44 , C12N2500/46
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号：US10829732B2
公开(公告)日：2020-11-10
申请号：US16151904
申请日：2018-10-04
Applicant: Genentech, Inc.
Inventor： Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号：US10676710B2
公开(公告)日：2020-06-09
申请号：US15997342
申请日：2018-06-04
Applicant: Genentech, Inc.
Inventor： Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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