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公开(公告)号:US20240093143A1
公开(公告)日:2024-03-21
申请号:US18497162
申请日:2023-10-30
Applicant: GENENTECH, INC.
Inventor: Natarajan Vijayasankaran , Steven J. Meier , Melissa S. Mun , Sharat Varma , Yi Yang , Boyan Zhang , Silvana R. Arevalo , Martin Gawlitzek , Veronica Carvalhal
CPC classification number: C12N5/0018 , C07K16/00 , C12N5/005 , C12P21/00 , C12N2500/24 , C12N2500/32 , C12N2500/38 , C12N2501/39
Abstract: Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided.
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公开(公告)号:US20220151221A1
公开(公告)日:2022-05-19
申请号:US17497330
申请日:2021-10-08
Applicant: Genentech, Inc.
Inventor: Angela Meier , Steven J. Meier , Phillip Duffy , Marcia Coyne , Kara Calhoun
Abstract: Provided herein are methods of freezing mammalian cells for storage or improving thaw recovery of cell banks comprising freezing mammalian cells in a freezing medium having a pH of 6.7 to 8.5.
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公开(公告)号:US10829732B2
公开(公告)日:2020-11-10
申请号:US16151904
申请日:2018-10-04
Applicant: Genentech, Inc.
Inventor: Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号:US10676710B2
公开(公告)日:2020-06-09
申请号:US15997342
申请日:2018-06-04
Applicant: Genentech, Inc.
Inventor: Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号:US11912823B2
公开(公告)日:2024-02-27
申请号:US17319886
申请日:2021-05-13
Applicant: Genentech, Inc.
Inventor: Ganesh Prasadh Vissvesvaran , Robert David Kiss , Steven J. Meier , Inchan Kwon , Kara Calhoun , Kate Winchester , Amelia Adams , Marion Glenn , Stefan Koenig , Alan Deese
CPC classification number: C08G65/30 , C07K16/00 , C12N5/0018 , C07K2317/14 , C08G2650/50 , C12N2500/50
Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.
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公开(公告)号:US10602739B2
公开(公告)日:2020-03-31
申请号:US15399666
申请日:2017-01-05
Applicant: Genentech, Inc.
Inventor: Angela Meier , Steven J. Meier , Phillip Duffy , Marcia Coyne , Kara Calhoun
Abstract: Provided herein are methods of freezing mammalian cells for storage or improving thaw recovery of cell banks comprising freezing mammalian cells in a freezing medium having a pH of 6.7 to 8.5.
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公开(公告)号:US10131873B2
公开(公告)日:2018-11-20
申请号:US14852311
申请日:2015-09-11
Applicant: Genentech, Inc.
Inventor: Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号:US10017732B2
公开(公告)日:2018-07-10
申请号:US14211416
申请日:2014-03-14
Applicant: Genentech, Inc.
Inventor: Natarajan Vijayasankaran , Steven J. Meier , Sharat Varma , Yi Yang
CPC classification number: C12N5/0018 , C07K16/00 , C07K2317/14 , C12N2500/30 , C12N2500/33 , C12N2500/44 , C12N2500/46
Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
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公开(公告)号:US12016328B2
公开(公告)日:2024-06-25
申请号:US17497330
申请日:2021-10-08
Applicant: Genentech, Inc.
Inventor: Angela Meier , Steven J. Meier , Phillip Duffy , Marcia Coyne , Kara Calhoun
CPC classification number: A01N1/0221 , A01N1/0284 , C12N5/0018 , C12N5/0682 , C12N2510/02
Abstract: Provided herein are methods of freezing mammalian cells for storage or improving thaw recovery of cell banks comprising freezing mammalian cells in a freezing medium having a pH of 6.7 to 8.5.
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公开(公告)号:US20240052392A1
公开(公告)日:2024-02-15
申请号:US18491555
申请日:2023-10-20
Applicant: GENENTECH, INC.
Inventor: Steven J. Meier , Melissa S. Mun , Natarajan Vijayasankaran , Sharat Varma , Yi Yang , Boyan Zhang , Silvana R. Arevalo , Martin Gawlitzek , Veronica Carvalhal
CPC classification number: C12P21/00 , C12N5/005 , C07K16/2839 , C07K16/00 , C12N2500/38 , C12N2500/32 , C07K2317/14 , C12N2511/00 , C12N2500/24 , C12N2501/39
Abstract: Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided.
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