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公开(公告)号：US20190025387A1
公开(公告)日：2019-01-24
申请号：US15658123
申请日：2017-07-24
发明人： Ernst Wolfang Stautner , Jan Henrik Ardenkjaer-Larsen , Patrick L. Padgett , Jonathan Alan Murray , Rui Chen , James Richard Trigger , Arnaud Comment , Albert Po-Fu Chen
CPC分类号： G01R33/31 , F25B19/005 , F25D19/006 , F25D21/002 , F25D29/001 , G01N1/42 , G01R33/282
摘要： A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.
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公开(公告)号：US20150091573A1
公开(公告)日：2015-04-02
申请号：US14038948
申请日：2013-09-27
申请人： General Electric Company , The United States of America, As Represented By The Secretary, Department of Health and Human Serv
发明人： Timothy William Skloss , Jonathan Alan Murray , Jan Henrik Ardenkjaer-Larsen , Murali K. Cherukuri , Marcelino Bernardo , Nallathamby Devasahayam
IPC分类号： G01R33/56
CPC分类号： G01R33/5601 , A61B5/055 , A61B2560/06 , G01R33/282
摘要： A system and method for transporting a hyperpolarized substance is disclosed. A transport vessel for transporting such a hyperpolarized substance includes a vessel housing, a chamber formed within the vessel housing that is configured to receive a container holding a hyperpolarized substance, and an electromagnet configured to generate a magnetic containment field about the chamber when a current is supplied thereto, the magnetic containment field comprising a homogeneous magnetic field. The transport vessel also includes a non-magnetic power source to supply the current to the electromagnet and a control circuit configured to selectively interrupt the supply of current to the electromagnet so as to control generation of the magnetic containment field, with the transport vessel being magnetically inert when the supply of current to the electromagnet is interrupted by the control circuit.
摘要翻译： 公开了一种运输超极化物质的系统和方法。 用于运输这种超极化物质的运输容器包括容器壳体，形成在容器壳体内的腔室，其构造成容纳容纳超极化物质的容器;以及电磁体，其构造成当电流为电流时产生围绕腔室的磁容纳场 提供给其，磁容纳场包括均匀的磁场。 输送容器还包括用于向电磁体提供电流的非磁性电源以及配置成选择性地中断向电磁体供应电流的控制电路，以便控制磁性容纳场的产生，运输容器是磁性的 当电磁铁供应电流被控制电路中断时，它是惰性的。
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公开(公告)号：US20190003653A1
公开(公告)日：2019-01-03
申请号：US15694669
申请日：2017-09-01
CPC分类号： F17C13/06 , A61J1/1406 , A61J1/165 , F16J15/022 , F16J15/067 , F17C3/085 , G01R33/282 , G01R33/31
摘要： Methods and systems are provided for a sealing system for a dynamic nuclear polarization (DNP) system. In one embodiment, a system comprises: a reservoir including an inlet opening; an outer tube; and a tapered seal shaped to seal against the inlet opening and the outer tube, the tapered seal including: a first section removably coupleable to a second section; a through-hole formed by a first plurality of inner surfaces of both the first section and the second section, the through-hole shaped to encircle the outer tube; and a vacuum channel extending through, from an outer surface to an inner surface of the first plurality of inner surfaces, one of the first section and second section. In this way, the tapered seal may be coupled around the fluid passage without inserting a tip of the fluid passage through the through-hole of the tapered seal, thereby maintaining a sterility of the system.
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公开(公告)号：US10578251B2
公开(公告)日：2020-03-03
申请号：US15694669
申请日：2017-09-01
摘要： Methods and systems are provided for a sealing system for a dynamic nuclear polarization (DNP) system. In one embodiment, a system comprises: a reservoir including an inlet opening; an outer tube; and a tapered seal shaped to seal against the inlet opening and the outer tube, the tapered seal including: a first section removably coupleable to a second section; a through-hole formed by a first plurality of inner surfaces of both the first section and the second section, the through-hole shaped to encircle the outer tube; and a vacuum channel extending through, from an outer surface to an inner surface of the first plurality of inner surfaces, one of the first section and second section. In this way, the tapered seal may be coupled around the fluid passage without inserting a tip of the fluid passage through the through-hole of the tapered seal, thereby maintaining a sterility of the system.
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公开(公告)号：US10481222B2
公开(公告)日：2019-11-19
申请号：US15658123
申请日：2017-07-24
发明人： Ernst Wolfgang Stautner , Jan Henrik Ardenkjaer-Larsen , Patrick L. Padgett , Jonathan Alan Murray , Rui Chen , James Richard Trigger , Arnaud Comment , Albert Po-Fu Chen
摘要： A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.
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公开(公告)号：US09874622B2
公开(公告)日：2018-01-23
申请号：US14038948
申请日：2013-09-27
申请人： General Electric Company , The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health
发明人： Timothy William Skloss , Jonathan Alan Murray , Jan Henrik Ardenkjaer-Larsen , Murali K. Cherukuri , Marcelino Bernardo , Nallathamby Devasahayam
CPC分类号： G01R33/5601 , A61B5/055 , A61B2560/06 , G01R33/282
摘要： A system and method for transporting a hyperpolarized substance is disclosed. A transport vessel for transporting such a hyperpolarized substance includes a vessel housing, a chamber formed within the vessel housing that is configured to receive a container holding a hyperpolarized substance, and an electromagnet configured to generate a magnetic containment field about the chamber when a current is supplied thereto, the magnetic containment field comprising a homogeneous magnetic field. The transport vessel also includes a non-magnetic power source to supply the current to the electromagnet and a control circuit configured to selectively interrupt the supply of current to the electromagnet so as to control generation of the magnetic containment field, with the transport vessel being magnetically inert when the supply of current to the electromagnet is interrupted by the control circuit.
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