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    Wireless ECG in implantable devices
    3.
    发明授权
    Wireless ECG in implantable devices 有权
    无线心电图在植入式设备

    公开(公告)号：US08301234B2

    公开(公告)日：2012-10-30

    申请号：US13288105

    申请日：2011-11-03

    申请人： Aaron R. McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    发明人： Aaron R. McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/3756

    摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

    摘要翻译： 诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。 通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。 各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗装置的表面上的电极的各种组合。

    WIRELESS ECG IN IMPLANTABLE DEVICES
    4.
    发明申请
    WIRELESS ECG IN IMPLANTABLE DEVICES 有权
    无线心电图在可植入的设备

    公开(公告)号：US20110022109A1

    公开(公告)日：2011-01-27

    申请号：US12893127

    申请日：2010-09-29

    申请人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    发明人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    IPC分类号： A61N1/365 ,  A61N1/375

    CPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/3756

    摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

    摘要翻译： 诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。 通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。 各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗装置的表面上的电极的各种组合。

    Detection of patient mortality by an implantable medical device
    5.
    发明授权
    Detection of patient mortality by an implantable medical device 有权
    通过可植入医疗设备检测患者死亡率

    公开(公告)号：US07050853B2

    公开(公告)日：2006-05-23

    申请号：US10614677

    申请日：2003-07-07

    申请人： Geng Zhang ,  Richard S. Sanders

    发明人： Geng Zhang ,  Richard S. Sanders

    IPC分类号： A61N1/362

    CPC分类号： A61B5/0031 ,  A61B5/0402 ,  A61B5/0464 ,  A61B5/0468 ,  A61B5/0535 ,  A61B5/0809 ,  A61B5/11 ,  A61B7/00 ,  A61N1/3702

    摘要： An implantable cardiac rhythm management device is programmed and configured to detect a death event. When such an event is detected, the device ceases recording of physiological data, thus preserving in the device's memory the data collected at and shortly before the time of death. A death event may be detected by detecting of an absence of intrinsic electrical activity in the patient's heart and a lack of an evoked response to a predetermined number of pacing pulses.

    摘要翻译： 可植入心律管理装置被编程和配置为检测死亡事件。 当检测到这样的事件时，设备停止记录生理数据，从而在设备的存储器中保存在死亡时间之前和不久之前收集的数据。 可以通过检测患者心脏中不存在固有电活动以及缺乏对预定数量的起搏脉冲的诱发反应来检测死亡事件。

    Autocapture pacing/sensing configuration
    6.
    发明授权
    Autocapture pacing/sensing configuration 有权
    自动采集起搏/感应配置

    公开(公告)号：US08224446B2

    公开(公告)日：2012-07-17

    申请号：US12415660

    申请日：2009-03-31

    申请人： Geng Zhang ,  Jungkuk Kim ,  Qingsheng Zhu

    发明人： Geng Zhang ,  Jungkuk Kim ,  Qingsheng Zhu

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3712 ,  A61N1/3716

    摘要： A cardiac electrical stimulation system that enhances the ability of the system to automatically detect whether an electrical stimulus results in heart capture or contraction. The cardiac electrical stimulation system may be utilized, for example, as a cardiac pacer or as a cardioverter defibrillator. The cardiac electrical stimulation system includes an electrical stimulation circuit that attenuates polarization voltages or “afterpotential” which develop at the heart tissue/electrode interface following the delivery of a stimulus to the heart tissue, which thereby allows the stimulation electrodes to be utilized to sense an evoked response to the electrical stimulus. The cardiac electrical stimulation system utilizes the stimulation electrodes to sense an evoked response, thereby eliminating the necessity for an indifferent electrode to sense an evoked response. The present invention allows accurate detection of an evoked response of the heart, to thereby determine whether each electrical stimulus results in capture.

    摘要翻译： 心脏电刺激系统，其增强系统自动检测电刺激是否导致心脏捕获或收缩的能力。 心脏电刺激系统可以用作例如心脏起搏器或心律转复除颤器。 心脏电刺激系统包括电刺激电路，该电刺激电路衰减在向心脏组织递送刺激之后在心脏组织/电极界面处发展的极化电压或“后电位”，从而允许刺激电极用于感测 诱发对电刺激的反应。 心脏电刺激系统利用刺激电极来感测诱发反应，从而消除无关电极感应诱发反应的必要性。 本发明允许精确检测心脏的诱发反应，从而确定每个电刺激是否导致捕获。

    GUIDEWIRE AND SIGNAL ANALYZER FOR PACING SITE OPTIMIZATION
    7.
    发明申请
    GUIDEWIRE AND SIGNAL ANALYZER FOR PACING SITE OPTIMIZATION 有权
    指南和信号分析仪用于PACING SITE OPTIMIZATION

    公开(公告)号：US20120130220A1

    公开(公告)日：2012-05-24

    申请号：US13293707

    申请日：2011-11-10

    申请人： Barun Maskara ,  Yinghong Yu ,  Bruce A. Tockman ,  Sunipa Saha ,  Martin McDaniel ,  Geng Zhang

    发明人： Barun Maskara ,  Yinghong Yu ,  Bruce A. Tockman ,  Sunipa Saha ,  Martin McDaniel ,  Geng Zhang

    IPC分类号： A61B5/042 ,  A61N1/36 ,  A61N1/39 ,  A61B19/00

    CPC分类号： A61N1/056 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/0472 ,  A61B5/6851 ,  A61N1/37241 ,  A61N2001/0585

    摘要： Cardiac lead implantation systems, devices, and methods for lead implantation are disclosed. An illustrative cardiac lead implantation system comprises a mapping guidewire including one or more electrodes configured for sensing cardiac electrical activity, a signal analyzer including an analysis module configured for analyzing an electrocardiogram signal sensed by the mapping guidewire, and a user interface configured for monitoring one or more hemodynamic parameters within the body. The sensed electrical activity signal can be used by the analysis module to compute a timing interval associated with ventricular depolarization.

    摘要翻译： 公开了用于引线植入的心脏引线植入系统，装置和方法。 示例性心脏引线植入系统包括：映射导丝，其包括被配置为感测心脏电活动的一个或多个电极;信号分析器，包括被配置用于分析由所述映射导丝所感测的心电图信号的分析模块;以及用户界面，被配置为监视一个或 更多血液动力学参数在体内。 感测的电活动信号可以被分析模块用于计算与心室去极化相关的定时间隔。

    MAXIMUM PACING RATE LIMITER SYSTEM
    8.
    发明申请
    MAXIMUM PACING RATE LIMITER SYSTEM 失效
    最大速率限制系统

    公开(公告)号：US20110230926A1

    公开(公告)日：2011-09-22

    申请号：US13115825

    申请日：2011-05-25

    申请人： Douglas R. Daum ,  Geng Zhang ,  Qingsheng Zhu ,  Gerrard M. Carlson ,  Julio C. Spinelli

    发明人： Douglas R. Daum ,  Geng Zhang ,  Qingsheng Zhu ,  Gerrard M. Carlson ,  Julio C. Spinelli

    IPC分类号： A61N1/365

    CPC分类号： A61N1/365

    摘要： A maximum pacing rate limiter for use in adaptive rate pacing in conjunction with a cardiac rhythm management system for a heart. The maximum pacing rate limiter may function to measure an interval, termed the ERT interval, between a paced ventricular evoked response and a T-wave. The maximum pacing rate limiter may further function to maintain the ERT interval at less than a certain percentage of the total cardiac cycle. In one disclosed embodiment, a maximum pacing rate limiter calculates an ERT rate based on the detected paced ventricular evoked response and the T-wave, and the pacing rate limiter module further communicates the minimum of the ERT rate and an adaptive-rate sensor indicated rate to a pacemaker.

    摘要翻译： 与心脏心律管理系统结合使用的适应性起搏速度的最大起搏速率限制器。 最大起搏速率限制器可以用于测量在起搏心室诱发反应和T波之间的称为ERT间期的间隔。 最大起搏速率限制器可进一步起作用以将ERT间期维持在小于总心律周期的一定百分比。 在一个公开的实施例中，最大起搏速率限制器基于检测到的起搏心室诱发反应和T波计算ERT率，并且起搏速率限制器模块进一步传达最小ERT率和自适应速率传感器指示率 到起搏器。

    Atrial Capture Verification
    9.
    发明申请
    Atrial Capture Verification 有权
    心房拍摄验证

    公开(公告)号：US20090306737A1

    公开(公告)日：2009-12-10

    申请号：US12540902

    申请日：2009-08-13

    申请人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

    发明人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

    IPC分类号： A61N1/37

    CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

    摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient's heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response.

    摘要翻译： 描述了用于将心脏反应分类为起搏刺激和/或预防逆行心脏传导的方法和系统。 在心脏周期内将起搏脉搏递送到患者心脏的心房后，系统在心房感测逆行P波。 该系统基于逆行P波的检测将起搏脉冲的心房响应分类。 该系统还可以感知心房诱发反应并且利用心房诱发反应来分类心脏起搏反应。

    Atrial retrograde management
    10.
    发明申请
    Atrial retrograde management 有权
    心房逆行管理

    公开(公告)号：US20060129199A1

    公开(公告)日：2006-06-15

    申请号：US11012692

    申请日：2004-12-15

    申请人： Geng Zhang ,  Ankur Garg

    发明人： Geng Zhang ,  Ankur Garg

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

    摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient's heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response. If capture is not detected, the system may deliver additional atrial pacing pulses to reduce atrial retrograde conduction. A backup pace may be delivered to prevent the atrial retrograde conduction if an atrial evoked response is not detected during a cardiac cycle. Alternatively, retrograde management may involve delaying a next scheduled pace may be until expiration of an atrial effective refractory period.

    摘要翻译： 描述了用于将心脏反应分类为起搏刺激和/或预防逆行心脏传导的方法和系统。 在心脏周期内将起搏脉搏递送到患者心脏的心房后，系统在心房感测逆行P波。 该系统基于逆行P波的检测将起搏脉冲的心房响应分类。 该系统还可以感知心房诱发反应并且利用心房诱发反应来分类心脏起搏反应。 如果未检测到捕获，则系统可能会传递额外的心房起搏脉冲以减少心房逆行传导。 如果在心动周期期间没有检测到心房诱发反应，则可以提供备份速度以防止心房逆行传导。 或者，逆行管理可能涉及延迟下一预定速度，直到心房有效不应期结束。