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1.发明授权公开(公告)号：US11898202B2
公开(公告)日：2024-02-13
申请号：US17686007
申请日：2022-03-03
申请人： Genomill Health Oy
IPC分类号： C12Q1/6865 , C12Q1/6806 , C12Q1/6869
CPC分类号： C12Q1/6865 , C12Q1/6806 , C12Q1/6869
摘要： The present invention disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the invention is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The invention includes one or more target-specific nucleic acid probes per genetic target and a bridge oligo or bridge oligo complex.
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公开(公告)号：US11970736B2
公开(公告)日：2024-04-30
申请号：US17899851
申请日：2022-08-31
申请人： Genomill Health Oy
IPC分类号： C12Q1/6869 , C12Q1/6855
CPC分类号： C12Q1/6869 , C12Q1/6855 , C12Q2600/156 , C12Q2600/16
摘要： The present disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the disclosed embodiments is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The disclosed embodiments includes two target-specific nucleic acid probes per genetic target, a barcode loop oligo and a bridge oligo or bridge oligo complex.
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3.发明公开公开(公告)号：US20240068010A1
公开(公告)日：2024-02-29
申请号：US17900109
申请日：2022-08-31
申请人： Genomill Health Oy
IPC分类号： C12Q1/6806 , C12Q1/6823 , C12Q1/6855 , C12Q1/6876
CPC分类号： C12Q1/6806 , C12Q1/6823 , C12Q1/6855 , C12Q1/6876 , C12Q2521/101 , C12Q2521/501
摘要： The present invention disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the invention is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The invention includes at least target-specific nucleic acid probes per genetic target (first probe, second probe and target-specific probe) and a bridge oligo or bridge oligo complex.
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公开(公告)号：US20220298569A1
公开(公告)日：2022-09-22
申请号：US17685964
申请日：2022-03-03
申请人： Genomill Health Oy
IPC分类号： C12Q1/6874
摘要： The present disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the present disclosure is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The disclosed embodiments includes one or more target-specific nucleic acid probes per genetic target (left probe and right probe) and a bridge oligo or bridge oligo complex.
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公开(公告)号：US20240254551A1
公开(公告)日：2024-08-01
申请号：US18612232
申请日：2024-03-21
申请人： Genomill Health Oy
IPC分类号： C12Q1/6869 , C12Q1/6855
CPC分类号： C12Q1/6869 , C12Q1/6855 , C12Q2600/156 , C12Q2600/16
摘要： The present invention disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the invention is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The invention includes two target-specific nucleic acid probes per genetic target, a barcode loop oligo and a bridge oligo or bridge oligo complex.
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公开(公告)号：US20240068022A1
公开(公告)日：2024-02-29
申请号：US17899851
申请日：2022-08-31
申请人： Genomill Health Oy
IPC分类号： C12Q1/6869
CPC分类号： C12Q1/6869 , C12Q1/6855 , C12Q2600/156 , C12Q2600/16
摘要： The present invention disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the invention is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The invention includes two target-specific nucleic acid probes per genetic target, a barcode loop oligo and a bridge oligo or bridge oligo complex.
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公开(公告)号：US11486003B2
公开(公告)日：2022-11-01
申请号：US17685964
申请日：2022-03-03
申请人： Genomill Health Oy
IPC分类号： C12P19/34 , C12Q1/6874
摘要： The present disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the present disclosure is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The disclosed embodiments includes one or more target-specific nucleic acid probes per genetic target (left probe and right probe) and a bridge oligo or bridge oligo complex.
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8.发明申请公开(公告)号：US20220298566A1
公开(公告)日：2022-09-22
申请号：US17686007
申请日：2022-03-03
申请人： Genomill Health Oy
IPC分类号： C12Q1/6865 , C12Q1/6806 , C12Q1/6869
摘要： The present invention disclosure relates to a next generation DNA sequencing method and use for accurate and massively parallel quantification of one or more nucleic acid targets, for example in large volumes of unpurified sample material. More particularly, the invention is related to a method and a kit comprising probes for detecting and quantifying genetic targets in complex samples. The invention includes one or more target-specific nucleic acid probes per genetic target and a bridge oligo or bridge oligo complex.
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