公开(公告)号：US20090133319A1

公开(公告)日：2009-05-28

申请号：US12083944

申请日：2006-12-15

申请人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, JR. ,  Benjamin Kenneth Smith

发明人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, JR. ,  Benjamin Kenneth Smith

IPC分类号： A01M1/20 ,  C07D413/10 ,  C07D413/14 ,  A01N43/80 ,  A01N63/00 ,  A01P7/04

CPC分类号： C07D413/14 ,  A01N43/80 ,  C07D261/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10 ,  C07D417/14

摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof wherein A1, A2 and A3 are independently selected from the group consisting of CR3 and N; B1 B2 and B3 are independently selected from the group consisting of CR2 and N; Q is a phenyl ring or a 5- or 6-membered saturated or unsaturated heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 haloalkylthio, C1-C6 alkylsulfinyl, C1-C6 haloalkylsufinyl, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, —CN, —NO2, —N(R4)R5, —C(W)N(R4)R5, —C(O)OR5 and R8; or —S(O)2N(R21)R22; —S(O)pR25 or —S(O)(═NR28)R29; R1, R2, R3, R4, R5, R8, R21, R22, R25, R28, R29; p and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中A1，A2和A3独立地选自CR3和N; B1 B2和B3独立地选自CR2和N; Q是苯环或5或6元饱和或不饱和杂环，每个环任选被一个或多个独立地选自卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 3 -C 6环烷基， C 1 -C 6卤代烷基，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基，C 1 -C 6烷基亚磺酰基，C 1 -C 6卤代烷基亚磺酰基， N（R4）R5，-C（W）N（R4）R5，-C（O）OR5和R8; 或-S（O）2 N（R 21）R 22; -S（O）p R 25或-S（O）（ - NR 28）R 29; R1，R2，R3，R4，R5，R8，R21，R22，R25，R28，R29; p和n如本公开中所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，包括使无脊椎害虫或其环境与生物有效量的本发明化合物或组合物接触。

公开(公告)号：US09073910B2

公开(公告)日：2015-07-07

申请号：US13037257

申请日：2011-02-28

申请人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, Jr. ,  Benjamin Kenneth Smith ,  Jeffrey Keith Long

发明人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, Jr. ,  Benjamin Kenneth Smith ,  Jeffrey Keith Long

IPC分类号： C07D413/14 ,  A01N43/80 ,  C07D261/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10 ,  C07D417/14

CPC分类号： C07D413/14 ,  A01N43/80 ,  C07D261/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10 ,  C07D417/14

摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A1, A2 and A3 are independently selected from the group consisting of CR3 and N; B1 B2 and B3 are independently selected from the group consisting of CR2 and N; Q is a phenyl ring or a 5- or 6-membered saturated or unsaturated heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 haloalkylthio, C1-C6 alkylsulfinyl, C1-C6 haloalkylsulfinyl, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, —CN, —NO2, —N(R4)R5, —C(W)N(R4)R5, —C(O)OR5 and R8; or —S(O)2N(R21)R22, —S(O)pR25 or —S(O)(═NR28)R29; and R1, R2, R3, R4, R5, R8, R21, R22, R25, R28, R29; p and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition' of the invention.

摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中A1，A2和A3独立地选自CR3和N; B1 B2和B3独立地选自CR2和N; Q是苯环或5或6元饱和或不饱和杂环，每个环任选被一个或多个独立地选自卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 3 -C 6环烷基， C 1 -C 6卤代烷基，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基，C 1 -C 6烷基亚磺酰基，C 1 -C 6卤代烷基亚磺酰基，C 1 -C 6烷基磺酰基， N（R4）R5，-C（W）N（R4）R5，-C（O）OR5和R8; 或-S（O）2 N（R 21）R 22，-S（O）p R 25或-S（O）（= NR 28）R 29; 和R 1，R 2，R 3，R 4，R 5，R 8，R 21，R 22，R 25，R 28，R 29; p和n如本公开中所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，其包括使无脊椎害虫或其环境与生物有效量的本发明的化合物或组合物接触。

公开(公告)号：US20120053051A9

公开(公告)日：2012-03-01

申请号：US13037257

申请日：2011-02-28

申请人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, JR. ,  Benjamin Kenneth Smith

发明人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, JR. ,  Benjamin Kenneth Smith

IPC分类号： A01N25/26 ,  C07D413/02 ,  C07D401/14 ,  A01N43/16 ,  A01N43/80 ,  A01N57/16 ,  A01N43/54 ,  A01N43/86 ,  A01N43/58 ,  A01N43/24 ,  A01N63/00 ,  C07D261/04 ,  A01N43/40

CPC分类号： C07D413/14 ,  A01N43/80 ,  C07D261/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10 ,  C07D417/14

摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A1, A2 and A3 are independently selected from the group consisting of CR3 and N; B1 B2 and B3 are independently selected from the group consisting of CR2 and N; Q is a phenyl ring or a 5- or 6-membered saturated or unsaturated heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 haloalkylthio, C1-C6 alkylsulfinyl, C1-C6 haloalkylsulfinyl, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, —CN, —NO2, —N(R4)R5, —C(W)N(R4)R5, —C(O)OR5 and R8; or —S(O)2N(R21)R22, —S(O)pR25 or —S(O)(═NR28)R29; and R1, R2, R3, R4, R5, R8, R21, R22, R25, R28, R29; p and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition' of the invention.

摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中A1，A2和A3独立地选自CR3和N; B1 B2和B3独立地选自CR2和N; Q是苯环或5或6元饱和或不饱和杂环，每个环任选被一个或多个独立地选自卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 3 -C 6环烷基， C 1 -C 6卤代烷基，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基，C 1 -C 6烷基亚磺酰基，C 1 -C 6卤代烷基亚磺酰基，C 1 -C 6烷基磺酰基， N（R4）R5，-C（W）N（R4）R5，-C（O）OR5和R8; 或-S（O）2 N（R 21）R 22，-S（O）p R 25或-S（O）（= NR 28）R 29; 和R 1，R 2，R 3，R 4，R 5，R 8，R 21，R 22，R 25，R 28，R 29; p和n如本公开中所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，其包括使无脊椎害虫或其环境与生物有效量的本发明的化合物或组合物接触。

公开(公告)号：US20110152081A1

公开(公告)日：2011-06-23

申请号：US13037257

申请日：2011-02-28

申请人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, JR. ,  Benjamin Kenneth Smith

发明人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, JR. ,  Benjamin Kenneth Smith

IPC分类号： A01N25/26 ,  C07D261/04 ,  C07D413/02 ,  C07D401/14 ,  A01N43/16 ,  A01N43/80 ,  A01N43/40 ,  A01N43/54 ,  A01N43/86 ,  A01N43/58 ,  A01N43/24 ,  A01N63/00 ,  A01N57/16

CPC分类号： C07D413/14 ,  A01N43/80 ,  C07D261/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10 ,  C07D417/14

摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A1, A2 and A3 are independently selected from the group consisting of CR3 and N; B1 B2 and B3 are independently selected from the group consisting of CR2 and N; Q is a phenyl ring or a 5- or 6-membered saturated or unsaturated heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 haloalkylthio, C1-C6 alkylsulfinyl, C1-C6 haloalkylsulfinyl, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, —CN, —NO2, —N(R4)R5, —C(W)N(R4)R5, —C(O)OR5 and R8; or —S(O)2N(R21)R22, —S(O)pR25 or —S(O)(═NR28)R29; and R1, R2, R3, R4, R5, R8, R21, R22, R25, R28, R29; p and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition' of the invention.

摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中A1，A2和A3独立地选自CR3和N; B1 B2和B3独立地选自CR2和N; Q是苯环或5或6元饱和或不饱和杂环，每个环任选被一个或多个独立地选自卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 3 -C 6环烷基， C 1 -C 6卤代烷基，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基，C 1 -C 6烷基亚磺酰基，C 1 -C 6卤代烷基亚磺酰基，C 1 -C 6烷基磺酰基， N（R4）R5，-C（W）N（R4）R5，-C（O）OR5和R8; 或-S（O）2 N（R 21）R 22，-S（O）p R 25或-S（O）（= NR 28）R 29; 和R 1，R 2，R 3，R 4，R 5，R 8，R 21，R 22，R 25，R 28，R 29; p和n如本公开中所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，其包括使无脊椎害虫或其环境与生物有效量的本发明的化合物或组合物接触。

公开(公告)号：US07897630B2

公开(公告)日：2011-03-01

申请号：US12083944

申请日：2006-12-15

申请人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, Jr. ,  Benjamin Kenneth Smith ,  Jeffrey Keith Long

发明人： George Philip Lahm ,  Kanu Maganbhai Patel ,  Thomas Francis Pahutski, Jr. ,  Benjamin Kenneth Smith ,  Jeffrey Keith Long

IPC分类号： C07D417/10 ,  C07D413/10 ,  C07D261/04 ,  A61K31/506 ,  A61K31/4439 ,  A61K31/427 ,  A61K31/422 ,  A61K31/42

CPC分类号： C07D413/14 ,  A01N43/80 ,  C07D261/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10 ,  C07D417/14

摘要： Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof wherein A1, A2 and A3 are independently selected from the group consisting of CR3 and N; B1 B2 and B3 are independently selected from the group consisting of CR2 and N; Q is a phenyl ring or a 5- or 6-membered saturated or unsaturated heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from halogen, C1-C6 alkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 haloalkylthio, C1-C6 alkylsulfinyl, C1-C6 haloalkylsufinyl, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, —CN, —NO2, —N(R4)R5, —C(W)N(R4)R5, —C(O)OR5 and R8; or —S(O)2N(R21)R22; —S(O)pR25 or —S(O)(═NR28)R29; R1, R2, R3, R4, R5, R8, R21, R22, R25, R28, R29; p and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

摘要翻译： 公开了式1的化合物，包括所有几何和立体异构体，N-氧化物及其盐，其中A1，A2和A3独立地选自CR3和N; B1 B2和B3独立地选自CR2和N; Q是苯环或5或6元饱和或不饱和杂环，每个环任选被一个或多个独立地选自卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 3 -C 6环烷基， C 1 -C 6卤代烷基，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基，C 1 -C 6烷基亚磺酰基，C 1 -C 6卤代烷基亚磺酰基， N（R4）R5，-C（W）N（R4）R5，-C（O）OR5和R8; 或-S（O）2 N（R 21）R 22; -S（O）p R 25或-S（O）（= NR 28）R 29; R1，R2，R3，R4，R5，R8，R21，R22，R25，R28，R29; p和n如本公开中所定义。 还公开了含有式1化合物和控制无脊椎动物害虫的方法的组合物，包括使无脊椎害虫或其环境与生物有效量的本发明化合物或组合物接触。

公开(公告)号：US08623890B2

公开(公告)日：2014-01-07

申请号：US13264159

申请日：2010-05-04

申请人： George Philip Lahm ,  Renee M. Lett ,  Brenton Todd Smith ,  Benjamin Kenneth Smith ,  C. Anne Daly

发明人： George Philip Lahm ,  Renee M. Lett ,  Brenton Todd Smith ,  Benjamin Kenneth Smith ,  C. Anne Daly

IPC分类号： A01N43/42 ,  A61K31/44 ,  C07D491/02 ,  C07D498/02

CPC分类号： A01N55/00 ,  A01N43/90

摘要： Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Z is O or S; and R1, R2, R3, Q and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or a composition of the invention.

公开(公告)号：US20140113934A1

公开(公告)日：2014-04-24

申请号：US14124730

申请日：2012-06-19

申请人： George Philip Lahm ,  Benjamin Kenneth Smith

发明人： George Philip Lahm ,  Benjamin Kenneth Smith

IPC分类号： C07D215/14 ,  C07D401/12 ,  A61K31/4709 ,  C07D409/12 ,  A61K31/47

CPC分类号： C07D215/14 ,  A61K31/47 ,  A61K31/4709 ,  C07D215/12 ,  C07D401/12 ,  C07D409/12

摘要： Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein L is (CR13aR13b)t, CR14═CR14, C≡C, CR15aR15bX, XCR15aR15b, CO, O, S(O)p, NR5, CONR5, NR5CO, NR5SO2 or SO2NR5; X is O, S, SO, SO2, or NR5; and Q, R1, R2, R3, R5, R13a, R13b, R14, R15a, R15b t, p, n and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for treating helminth infections comprising administration to an animal a parasiticidally effective amount of a compound or a composition of the invention.

摘要翻译： 公开了式1，N-氧化物及其盐的化合物，其中L为（CR13aR13b）t，CR14 = CR14，C≡C，CR15aR15bX，XCR15aR15b，CO，O，S（O）p，NR5，CONR5，NR5CO ，NR5SO2或SO2NR5; X是O，S，SO，SO 2或NR 5; 和Q，R1，R2，R3，R5，R13a，R13b，R14，R15a，R15b，t，p，n和m如本公开所定义。 还公开了含有式1化合物和治疗蠕虫感染的方法的组合物，其包括给予动物杀寄生虫有效量的本发明化合物或组合物。

公开(公告)号：US20120114624A1

公开(公告)日：2012-05-10

申请号：US13264159

申请日：2010-05-04

申请人： George Philip Lahm ,  Renee M. Lett ,  Brenton Todd Smith ,  Benjamin Kenneth Smith ,  C. Anne Daly

发明人： George Philip Lahm ,  Renee M. Lett ,  Brenton Todd Smith ,  Benjamin Kenneth Smith ,  C. Anne Daly

IPC分类号： A01N43/42 ,  A01N43/22 ,  A01N57/28 ,  A01N59/14 ,  A01P5/00 ,  A01N57/16 ,  A01N57/12 ,  A01N43/54 ,  A01N43/88 ,  A01N63/00 ,  C07D471/04 ,  A01N43/68

CPC分类号： A01N55/00 ,  A01N43/90

摘要： Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Z is O or S; and R1, R2, R3, Q and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or a composition of the invention.

摘要翻译： 公开了式1，N-氧化物及其盐的化合物，其中Z为O或S; 并且R1，R2，R3，Q和n如本公开所定义。 还公开了含有式1化合物和控制寄生线虫的方法的组合物，其包括使寄生线虫或其环境与生物有效量的本发明化合物或组合物接触。

公开(公告)号：US07674936B2

公开(公告)日：2010-03-09

申请号：US11803170

申请日：2007-05-11

申请人： Kenneth Andrew Hughes ,  George Philip Lahm ,  Thomas Paul Selby ,  Benjamin Kenneth Smith ,  William Thomas Zimmerman

发明人： Kenneth Andrew Hughes ,  George Philip Lahm ,  Thomas Paul Selby ,  Benjamin Kenneth Smith ,  William Thomas Zimmerman

IPC分类号： C07C211/00

CPC分类号： C07D213/70 ,  A01N41/06 ,  A01N43/56 ,  C07C311/21 ,  C07C311/46 ,  C07D401/04

摘要： Disclosed are compounds of Formula I, their N-oxides and agriculturally suitable salts wherein J is a phenyl ring, a 5- or 6-membered heteroaromatic ring or an aromatic 8-, 9- or 10-membered fused carbobicyclic or heterobicyclic ring system wherein each ring or ring system is substituted with from one to four substituents independently selected from R5; K is —NR1C(=A)-, —N═C(GR6)— or —NR1SO2—; L is —C(═B)NR2—, —C(GR6)═N—, —SO2NR2—, —C(═B)O— or —C(═B)—; and A, B, G, R1, R2, R3, R4, R5, R6 and n are as defined in the disclosure. Also disclosed are methods for controlling invertebrate pests comprising contacting the pests or their environment with a biologically effective amount of a compound of Formula I and compositions containing the compounds of Formula I. Intermediate compounds useful in preparing the compounds of Formula I are also disclosed.

摘要翻译： 公开了式I化合物，其N-氧化物和农业上合适的盐，其中J是苯环，5或6元杂芳环或芳族8-，9-或10-元稠合的碳双环或杂双环体系，其中 每个环或环系被1-4个独立地选自R5的取代基取代; K是-NR1C（= A） - ， - N = C（GR6） - 或-NR1SO2-; L是-C（= B）NR 2 - ， - C（GR 6）N - ， - SO 2 NR 2 - ， - C（= B）O-或-C（= B） - ; 并且A，B，G，R 1，R 2，R 3，R 4，R 5，R 6和n如本公开所定义。 还公开了用于控制无脊椎害虫的方法，包括使害虫或其环境与生物有效量的式I化合物和含有式I化合物的组合物接触。还公开了可用于制备式I化合物的中间体化合物。