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    Thiazolidinedione analogues for the treatment of metabolic diseases
    1.
    发明授权
    Thiazolidinedione analogues for the treatment of metabolic diseases 有权
    噻唑烷二酮类似物用于治疗代谢性疾病

    公开(公告)号：US08067450B2

    公开(公告)日：2011-11-29

    申请号：US12677541

    申请日：2008-09-15

    申请人： Gerard R. Colca ,  Robert C. Gadwood ,  Tim Parker

    发明人： Gerard R. Colca ,  Robert C. Gadwood ,  Tim Parker

    IPC分类号： A61K31/426 ,  C07D277/02

    CPC分类号： C07D277/34

    摘要： The present invention relates to thiazolidinedione analogues that are useful for treating hypertension, diabetes, and inflammatory diseases. Formula (I), wherein: each of R1 and R4 is independently selected from H, halo, aliphatic, and alkoxy, wherein the aliphatic and alkoxy are optionally substituted with 1-3 of halo; R2 is halo, hydroxy, or optionally substituted aliphatic, and R′2 is H, or R2 and R′2 together form oxo; R3 is H; and Ring A is a phenyl.

    摘要翻译： 本发明涉及可用于治疗高血压，糖尿病和炎性疾病的噻唑烷二酮类似物。 式（I），其中：R 1和R 4各自独立地选自H，卤素，脂族和烷氧基，其中脂族和烷氧基任选被1-3个卤素取代; R2是卤素，羟基或任选取代的脂族基，R'2是H，或R 2和R'2一起形成氧代; R3为H; 环A是苯基。

    Thiazolidinedione Analogues For The Treatment Of Hypertension
    2.
    发明申请
    Thiazolidinedione Analogues For The Treatment Of Hypertension 有权
    噻唑烷二酮类似物治疗高血压

    公开(公告)号：US20100222399A1

    公开(公告)日：2010-09-02

    申请号：US12677541

    申请日：2008-09-15

    申请人： Gerard R. Colca ,  Robert C. Gadwood ,  Tim Parker

    发明人： Gerard R. Colca ,  Robert C. Gadwood ,  Tim Parker

    IPC分类号： A61K31/425 ,  C07D277/06 ,  A61P9/12

    CPC分类号： C07D277/34

    摘要： The present invention relates to thiazolidinedione analogues that are useful for treating hypertension, diabetes, and inflammatory diseases. Formula (I), wherein: each of R1 and R4 is independently selected from H, halo, aliphatic, and alkoxy, wherein the aliphatic and alkoxy are optionally substituted with 1-3 of halo; R2 is halo, hydroxy, or optionally substituted aliphatic, and R′2 is H, or R2 and R′2 together form oxo; R3 is H; and Ring A is a phenyl.

    摘要翻译： 本发明涉及可用于治疗高血压，糖尿病和炎性疾病的噻唑烷二酮类似物。 式（I），其中：R 1和R 4各自独立地选自H，卤素，脂族和烷氧基，其中脂族和烷氧基任选被1-3个卤素取代; R2是卤素，羟基或任选取代的脂族基，R'2是H，或R 2和R'2一起形成氧代; R3为H; 环A是苯基。

    Automatic routing system with variable width interconnect
    5.
    发明授权
    Automatic routing system with variable width interconnect 有权
    具有可变宽度互连的自动路由系统

    公开(公告)号：US08479139B1

    公开(公告)日：2013-07-02

    申请号：US12833886

    申请日：2010-07-09

    申请人： Graham Baldsdon ,  Jeremy Birch ,  Mark Williams ,  Mark Waller ,  Tim Parker ,  Fumiaki Sato

    发明人： Graham Baldsdon ,  Jeremy Birch ,  Mark Williams ,  Mark Waller ,  Tim Parker ,  Fumiaki Sato

    IPC分类号： G06F17/50

    CPC分类号： G06F17/5077 ,  G06F2217/78

    摘要： A system automatically routes interconnect of an integrated circuit design using variable width interconnect lines. For example, a first automatically routed interconnect may have a different width from a second automatically routed interconnect. The system will vary the width of the interconnect lines based on certain factors or criteria. These factors include current or power handling, reliability, electromigration, voltage drops, self-heating, optical proximity effects, or other factors, or combinations of these factors. The system may use a gridded or a gridless (or shape-based) approach.

    摘要翻译： 系统使用可变宽度的互连线路自动路由集成电路设计的互连。 例如，第一自动路由互连可以具有与第二自动路由互连不同的宽度。 系统将根据某些因素或标准改变互连线的宽度。 这些因素包括电流或功率处理，可靠性，电迁移，电压降，自热，光学邻近效应或其他因素，或这些因素的组合。 该系统可以使用网格或无网格（或基于形状的）方法。

    Design automation using spine routing
    6.
    发明授权
    Design automation using spine routing 有权
    使用脊柱路由设计自动化

    公开(公告)号：US07802208B1

    公开(公告)日：2010-09-21

    申请号：US11838704

    申请日：2007-08-14

    申请人： Mark Waller ,  Tim Parker ,  Mark Williams ,  Jeremy Birch ,  Graham Balsdon ,  Fumiako Sato

    发明人： Mark Waller ,  Tim Parker ,  Mark Williams ,  Jeremy Birch ,  Graham Balsdon ,  Fumiako Sato

    IPC分类号： G06F17/50

    CPC分类号： G06F17/5077

    摘要： A method and technique of routing interconnects of an integrated circuit providing improved routing quality. In an embodiment of the invention, the technique provides linear spine interconnect routing. In memory array blocks, such as in DRAM and SRAM memory designs, connected pins are generally separated by large distances in a first direction and small distances in a second direction, or a spine or channel region. A route area is defined within the spine region. In one embodiment, obstacles in the route area are identified and corresponding forbidden areas are demarcated. The linear spine interconnect is routed in the first direction within the route area while avoiding the forbidden areas. Pins are connected to the spine interconnect by stitching interconnects. Stitching interconnects are generally routed in the second direction.

    摘要翻译： 提供提供改进的路由质量的集成电路的互连路由的方法和技术。 在本发明的一个实施例中，该技术提供线性脊柱互连路由。 在诸如DRAM和SRAM存储器设计的存储器阵列块中，连接的引脚通常在第一方向上分开大距离，在第二方向或脊柱或通道区域上分开小距离。 在脊椎区域内定义路线区域。 在一个实施例中，识别路线区域中的障碍物并且划定对应的禁止区域。 线性脊线互连在路线区域内沿第一方向路由，同时避免禁止区域。 引脚通过缝合互连连接到脊柱互连。 缝合互连通常沿第二方向布线。

    Method of automatically routing nets according to current density rules
    8.
    发明授权
    Method of automatically routing nets according to current density rules 有权
    根据当前密度规则自动布线网络的方法

    公开(公告)号：US07131096B1

    公开(公告)日：2006-10-31

    申请号：US10709843

    申请日：2004-06-01

    申请人： Graham Balsdon ,  Jeremy Birch ,  Mark Williams ,  Mark Waller ,  Tim Parker ,  Fumiaki Sato

    发明人： Graham Balsdon ,  Jeremy Birch ,  Mark Williams ,  Mark Waller ,  Tim Parker ,  Fumiaki Sato

    IPC分类号： G06F17/50

    CPC分类号： G06F17/5077

    摘要： A technique will automatically route interconnect of an integrated circuit while taking into consideration current density rules. In an implementation, the technique uses a shape-based approach where a grid is not used. Based on data input including current density and a frequency of each net, the technique will determine the current requirements for each net. In an implementation, the technique forms a Steiner tree for a net, and routs using the Steiner tree. The technique widens nets having greater current requirements; adjacent wiring may be pushed aside to create sufficient space for wider nets.

    摘要翻译： 一种技术将自动路由集成电路的互连，同时考虑电流密度规则。 在实现中，该技术使用基于形状的方法，其中不使用网格。 基于数据输入，包括电流密度和每个网络的频率，该技术将确定每个网络的当前要求。 在实现中，该技术为网络形成Steiner树，并使用Steiner树进行路由。 该技术扩大了具有更大电流要求的网络; 可以将相邻的布线推到一边以产生用于更宽的网的足够的空间。

    Toner receptive coating
    9.
    发明授权
    Toner receptive coating 失效
    调色剂接受涂层

    公开(公告)号：US4958173A

    公开(公告)日：1990-09-18

    申请号：US444119

    申请日：1989-11-30

    申请人： John J. Fitch ,  Tim Parker ,  Alfred T. Bouchard, Jr. ,  Mary Sullivan

    发明人： John J. Fitch ,  Tim Parker ,  Alfred T. Bouchard, Jr. ,  Mary Sullivan

    IPC分类号： G03G7/00 ,  G03G13/16

    CPC分类号： G03G7/0026 ,  G03G13/16 ,  G03G7/004

    摘要： The invention comprises a toner receptive coating for substrates, typically paper, label or tag stock, for use in conventional printers such as ion deposition printers and photostatic copiers. The coating on paper or polymeric film improves the print density and durability of text or images transferred thereto from printers or copiers, particularly those which employ dry magnetic toner. The coating eliminates the need to use heat fusing to fix the transferred toned image to the substrate. The coating is composed of pressure sensitive polymeric binder material and particulate fillers. The polymeric binder has a glass transition temperature less than 20.degree. C. preferably a glass transition temperature between -10.degree. C. and +10.degree. C. The fillers include a polymeric filler, typically a polyethylene wax or a polyethylene/polytetrafluoroethylene wax mixture and a mineral filler, typically particulate silicon dioxide. The receptive coating also improves the smudge resistance of transferred toned images, particularly when employing dry magnetic toner. The coating can be used to fix (without heat fusing) the transferred toned image to paper, tag or label stock that has been coated with a pressure sensitive adhesive on the opposite side.

    摘要翻译： 本发明包括用于基板的调色剂接受涂层，通常为纸张，标签或标签纸，用于常规打印机，例如离子沉积打印机和静电复印机。 纸或聚合物膜上的涂层改善了从打印机或复印机，特别是使用干磁性调色剂的打印机或复印机转印到其上的文本或图像的印刷密度和耐久性。 该涂层消除了使用热融合将转印的调色图像固定到基底的需要。 涂层由压敏聚合物粘合剂材料和颗粒填料组成。 聚合物粘合剂的玻璃化转变温度低于20℃，优选玻璃化转变温度在-10℃至+ 10℃之间。填料包括聚合物填料，通常为聚乙烯蜡或聚乙烯/聚四氟乙烯蜡混合物， 矿物填料，通常为二氧化硅颗粒。 接受涂层还改善了转印调色图像的防污染性，特别是当使用干磁性调色剂时。 涂层可以用于将转印的调色图像固定（没有热熔）到在相对侧上涂覆有压敏粘合剂的纸张，标签或标签纸。

    Automation using spine routing
    10.
    发明授权
    Automation using spine routing 有权
    自动化使用脊柱路由

    公开(公告)号：US08479141B1

    公开(公告)日：2013-07-02

    申请号：US13352232

    申请日：2012-01-17

    申请人： Mark Waller ,  Tim Parker ,  Mark Williams ,  Jeremy Birch ,  Graham Balsdon ,  Fumiako Sato

    发明人： Mark Waller ,  Tim Parker ,  Mark Williams ,  Jeremy Birch ,  Graham Balsdon ,  Fumiako Sato

    IPC分类号： G06F17/50

    CPC分类号： G06F17/5077

    摘要： A method and technique of routing interconnects of an integrated circuit providing improved routing quality. In an embodiment of the invention, the technique provides linear spine interconnect routing. In memory array blocks, such as in DRAM and SRAM memory designs, connected pins are generally separated by large distances in a first direction and small distances in a second direction, or a spine or channel region. A route area is defined within the spine region. In one embodiment, obstacles in the route area are identified and corresponding forbidden areas are demarcated. The linear spine interconnect is routed in the first direction within the route area while avoiding the forbidden areas. Pins are connected to the spine interconnect by stitching interconnects. Stitching interconnects are generally routed in the second direction.

    摘要翻译： 提供提供改进的路由质量的集成电路的互连路由的方法和技术。 在本发明的一个实施例中，该技术提供线性脊柱互连路由。 在诸如DRAM和SRAM存储器设计的存储器阵列块中，连接的引脚通常在第一方向上分开大距离，在第二方向或脊柱或通道区域上分开小距离。 在脊椎区域内定义路线区域。 在一个实施例中，识别路线区域中的障碍物并且划定对应的禁止区域。 线性脊线互连在路线区域内沿第一方向路由，同时避免禁止区域。 引脚通过缝合互连连接到脊柱互连。 缝合互连通常沿第二方向布线。