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1.发明授权Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents 有权邻氨基苯甲酰胺及其衍生物作为化妆品和药剂公开(公告)号：US08203016B2
公开(公告)日：2012-06-19
申请号：US10535985
申请日：2003-11-20
申请人： Gerhard Schmaus , Holger Joppe , Martinia Herrmann , Christopher Sabater-Lüntzel , Tobias Vössing
发明人： Gerhard Schmaus , Holger Joppe , Martinia Herrmann , Christopher Sabater-Lüntzel , Tobias Vössing
IPC分类号： C07C207/00 , C07C205/00 , C07C229/00
CPC分类号： A61Q19/00 , A61K8/44 , A61K31/196 , A61K2800/75 , A61K2300/00
摘要： The use of specific compounds of the Formula 1 (and also corresponding mixtures) in particular as cosmetic agents for the inhibition of the substance P-induced release of histamine from mast cells is described.
摘要翻译： 描述了使用特定的式1化合物（以及相应的混合物），特别是作为用于抑制P诱导的组胺从肥大细胞释放的物质的化妆品。
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2.发明申请ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS 有权作为化妆品和药物活性化合物的安非他酮酸及其衍生物公开(公告)号：US20120315233A1
公开(公告)日：2012-12-13
申请号：US13524374
申请日：2012-06-15
申请人： Gerhard Schmaus , Holger Joppe , Martina Herrmann , Christopher Sabater-Luntzel , Tobias Vössing
发明人： Gerhard Schmaus , Holger Joppe , Martina Herrmann , Christopher Sabater-Luntzel , Tobias Vössing
IPC分类号： A61K31/196 , A61K31/4164 , A61K31/4412 , A61P17/00 , A61P31/04 , A61P31/10 , A61P17/04 , A61P37/08 , A61K31/24 , A61K31/722
CPC分类号： A61Q19/00 , A61K8/44 , A61K31/196 , A61K2800/75 , A61K2300/00
摘要： The use of specific compounds of the Formula 1 (and also corresponding mixtures) in particular as cosmetic agents for the inhibition of the substance P-induced release of histamine from mast cells is described.
摘要翻译： 描述了使用特定的式1化合物（以及相应的混合物），特别是作为用于抑制P诱导的组胺从肥大细胞释放的物质的化妆品。
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3.发明授权Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds 有权茴香酰胺及其衍生物作为化妆品和药物活性化合物公开(公告)号：US08409552B2
公开(公告)日：2013-04-02
申请号：US13524374
申请日：2012-06-15
申请人： Gerhard Schmaus , Holger Joppe , Martina Herrmann , Christopher Sabater-Luntzel , Tobias Vössing
发明人： Gerhard Schmaus , Holger Joppe , Martina Herrmann , Christopher Sabater-Luntzel , Tobias Vössing
CPC分类号： A61Q19/00 , A61K8/44 , A61K31/196 , A61K2800/75 , A61K2300/00
摘要： The use of specific compounds of the Formula 1 (and also corresponding mixtures) in particular as cosmetic agents for the inhibition of the substance P-induced release of histamine from mast cells is described.
摘要翻译： 描述了使用特定的式1化合物（以及相应的混合物），特别是作为用于抑制P诱导的组胺从肥大细胞释放的物质的化妆品。
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4.发明申请Synergistic mixtures of at least one 1,2 alkanediol such as 1,2-hexanediol and 1,2-octanediol with a further compound having antimicrobial properties 审中-公开至少一种1,2-链烷二醇如1,2-己二醇和1,2-辛二醇的协同混合物与具有抗微生物性质的其它化合物公开(公告)号：US20070265352A1
公开(公告)日：2007-11-15
申请号：US11254346
申请日：2005-10-20
IPC分类号： A61K31/047 , A01N31/02 , A01P1/00 , A61P31/00 , A23L1/015
CPC分类号： A23L3/3481 , A01N31/02 , A61K31/047 , A01N35/06 , A01N37/06 , A01N37/40 , A01N37/44 , A01N47/12 , A01N49/00 , A01N2300/00
摘要： Antimicrobial active compositions and substances comprising at least one, preferably two, unbranched (straight-chain) 1,2-alkanediols and preferably a further preservative and also to products containing such mixtures in an antimicrobially effective quantity. One example of an antimicrobial mixture comprises: (a) 1,2-hexanediol and 1,2-octanediol and also optionally 1,2-pentanediol and/or 1,2-decanediol and (b) one, two or more substances selected from the group consisting of potassium sorbate, parabens and iodopropynyl butylcarbamate (IPBC).
摘要翻译： 抗微生物活性组合物和包含至少一种，优选两种非支链（直链）1,2-链烷二醇，优选另外的防腐剂的物质，以及含有这些混合物的产品，其抗微生物有效量。 抗微生物混合物的一个实例包括：（a）1,2-己二醇和1,2-辛二醇，以及任选的1,2-戊二醇和/或1,2-癸二醇和（b）一种，两种或更多种选自 由山梨酸钾，对羟基苯甲酸酯和碘丙炔基丁基氨基甲酸酯（IPBC）组成的组。
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5.发明授权Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use 有权抗微生物活性的4-甲基-4-芳基-2-戊醇，其制备和应用公开(公告)号：US07119123B2
公开(公告)日：2006-10-10
申请号：US10790770
申请日：2004-03-03
申请人： Gerhard Schmaus , Holger Joppe
发明人： Gerhard Schmaus , Holger Joppe
IPC分类号： A61K31/045
CPC分类号： A61Q19/00 , A01N31/04 , A01N31/08 , A01N31/14 , A61K8/34 , A61Q5/006 , A61Q15/00 , A61Q17/005 , C07C33/20
摘要： Antimicrobially active 4-methyl-4-aryl-2-pentanols of the Formula 1 below, methods for the preparation of these compounds and their use as antimicrobial active compounds are described. Surprisingly, compounds of the Formula 1 for which: R=hydrogen, hydroxyl, alkoxy group with up to 10 C atoms, straight-chain or branched, saturated or unsaturated alkyl with up to 10 C atoms, alkylthioether group with up to 10 C atoms, the alkylthioether group being bonded to the aromatic ring via a thioether bridge, fluorine, chlorine, bromine, iodine, or alkyl with up to 10 C atoms that is interrupted by one or more oxygen and/or sulphur atoms, have proved to be antimicrobially active.
摘要翻译： 描述了下式1的抗微生物活性的4-甲基-4-芳基-2-戊醇，这些化合物的制备方法及其作为抗微生物活性化合物的用途。 令人惊奇的是，其中：R =氢，羟基，至多10个碳原子的烷氧基，具有至多10个C原子的直链或支链，饱和或不饱和的烷基，具有高达10 C原子的烷硫醚基的式1化合物 通过硫醚桥，氟，氯，溴，碘或具有多达10个C原子的被一个或多个氧和/或硫原子间隔的烷基，烷基硫醚基团与芳环结合，已被证明是抗微生物 活性。
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公开(公告)号：US20070098655A1
公开(公告)日：2007-05-03
申请号：US10558364
申请日：2004-05-24
IPC分类号： A61K8/31
CPC分类号： A61K8/347 , A23L5/41 , A61K2800/782 , A61Q5/08 , A61Q19/02
摘要： Novel uses of compounds of the Formula 1 or mixtures of substances that contain one more compounds of the Formula 1, are described. The said compounds are suitable as agents against skin and hair browning, for combating age spots and for the inhibition of the undesired browning of foods.
摘要翻译： 描述了式1化合物或含有另外一种式1化合物的物质混合物的新用途。 所述化合物适合作为抗皮肤和毛发褐变的药剂，用于对抗老年斑和抑制食物的不期望的褐变。
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公开(公告)号：US09655824B2
公开(公告)日：2017-05-23
申请号：US10558364
申请日：2004-05-24
CPC分类号： A61K8/347 , A23L5/41 , A61K2800/782 , A61Q5/08 , A61Q19/02
摘要： Novel uses of compounds of the Formula 1 or mixtures of substances that contain one more compounds of the Formula 1, are described. The said compounds are suitable as agents against skin and hair browning, for combating age spots and for the inhibition of the undesired browning of foods.
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公开(公告)号：US07247295B2
公开(公告)日：2007-07-24
申请号：US10381386
申请日：2002-06-19
申请人： Gerhard Schmaus , Martina Herrmann , Holger Joppe
发明人： Gerhard Schmaus , Martina Herrmann , Holger Joppe
摘要： The invention relates to a method for inhibiting the growth of organisms causing body odor on a human or animal body. The invention comprises the following step: topical application of 1,2-decanediol, wherein the amount of 1,2-decanediol applied is sufficient to inhibit the growth of organisms forming body odor at the site of application.
摘要翻译： 本发明涉及一种抑制人体或动物身体引起体臭的生物生长的方法。 本发明包括以下步骤：局部施用1,2-癸二醇，其中施用的1,2-癸二醇的量足以抑制在施用部位形成体臭的生物的生长。
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公开(公告)号：US07582681B2
公开(公告)日：2009-09-01
申请号：US10502132
申请日：2002-10-17
申请人： Gerhard Schmaus , Sabine Lange , Holger Joppe
发明人： Gerhard Schmaus , Sabine Lange , Holger Joppe
IPC分类号： A01N31/00 , A61K31/045 , A61K9/12
CPC分类号： A61Q19/00 , A01N31/02 , A61K8/34 , A61K8/345 , A61K2800/524 , A61K2800/59 , A61Q15/00 , A61Q17/005 , A01N39/00 , A01N37/34 , A01N2300/00
摘要： The use of mixtures of two, three or more straight-chain 1,2-alkanediols, the chains lengths of which (i) are different and (ii) in each case are in the range of 5 to 10 C atoms, as antimicrobial active compounds is described. Compared with the pure 1,2-alkanediols, the mixtures have a synergistically intensified action.
摘要翻译： 使用两个，三个或更多个直链1,2-链烷二醇的混合物，其链长（i）不同，（ii）在每种情况下为5至10个C原子的范围，作为抗微生物活性物质 描述了化合物。 与纯1,2-链烷二醇相比，混合物具有协同增强的作用。
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10.发明申请Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents 有权邻氨基苯甲酰胺及其衍生物作为化妆品和药剂公开(公告)号：US20060089413A1
公开(公告)日：2006-04-27
申请号：US10535985
申请日：2003-11-20
申请人： Gerhard Schmaus , Holger Joppe , Martina Herrmann , Christopher Sabater-Luntzel , Tobias Vossing
发明人： Gerhard Schmaus , Holger Joppe , Martina Herrmann , Christopher Sabater-Luntzel , Tobias Vossing
IPC分类号： A61K31/195 , C07C235/72
CPC分类号： A61Q19/00 , A61K8/44 , A61K31/196 , A61K2800/75 , A61K2300/00
摘要： The use of specific compounds of the Formula 1 (and also corresponding mixtures) in particular as cosmetic agents for the inhibition of the substance P-induced release of histamine from mast cells is described.
摘要翻译： 描述了使用特定的式1化合物（以及相应的混合物），特别是作为用于抑制P诱导的组胺从肥大细胞释放的物质的化妆品。
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