SYNERGISTIC ACTIVE PREPARATIONS COMPRISING DIPHENYLMETHANE DERIVATIVES AND FURTHER SKIN AND/OR HAIR LIGHTENING AND/OR SENILE KERATOSIS REDUCING COMPOUNDS
    1.
    发明申请
    SYNERGISTIC ACTIVE PREPARATIONS COMPRISING DIPHENYLMETHANE DERIVATIVES AND FURTHER SKIN AND/OR HAIR LIGHTENING AND/OR SENILE KERATOSIS REDUCING COMPOUNDS 审中-公开
    包含二苯基甲基衍生物的协同活性制剂和进一步的皮肤和/或头发亮度和/或高效减毒化合物

    公开(公告)号:US20090148391A1

    公开(公告)日:2009-06-11

    申请号:US12159951

    申请日:2007-01-05

    摘要: The present invention relates to specific synergistic active skin- and/or hair-lightening and/or senile keratosis-reducing (cosmetic or pharmaceutical) preparations comprising a mixture comprising or consisting of a) a tyrosinase-inhibiting amount of one or more compounds of the formula 1:  wherein: R1 is hydrogen, methyl, straight-chain or branched alkyl having 2-4 C atoms, OH or halogen, R2 is hydrogen, methyl or straight-chain or branched alkyl having 2-5 C atoms, R3 is methyl or straight-chain or branched alkyl having 2-5 C atoms, and R4 and R5 are, independently of one another hydrogen, methyl, straight-chain or branched alkyl having 2-5 C atoms, OH or halogen and b) a skin- and/or hair lightening and/or senile keratosis-reducing amount of one or more compounds selected from the group consisting of (i) chelating agents, (ii) phenolic derivatives, plant extracts with an amount of phenolic derivatives and (iii) organic acid derivatives as well as uses thereof.

    摘要翻译: 本发明涉及具体的协同增效活性皮肤和/或发发轻度和/或老年角化病减少剂(化妆品或药物)制剂,其包含混合物,其包含或由以下组成:a)酪氨酸酶抑制量的一种或多种化合物 式1:其中:R1是氢,甲基,具有2-4个C原子的直链或支链烷基,OH或卤素,R2是氢,甲基或具有2-5个C原子的直链或支链烷基,R3是甲基 或具有2-5个C原子的直链或支链烷基,R 4和R 5彼此独立地为具有2-5个C原子的氢,甲基,直链或支链烷基,OH或卤素,和b) 和/或毛发发光和/或老年性角化病减少量的一种或多种选自(i)螯合剂,(ii)酚衍生物,具有一定量酚衍生物的植物提取物和(iii)有机酸 衍生物及其用途。

    Skin Model
    4.
    发明申请
    Skin Model 审中-公开
    皮肤模型

    公开(公告)号:US20080138850A1

    公开(公告)日:2008-06-12

    申请号:US11948543

    申请日:2007-11-30

    IPC分类号: C12Q1/02

    CPC分类号: G01N33/5088

    摘要: The present invention relates to the use of a pig skin sample as a skin model, particularly for the assessment of pharmacological and cosmetic effects.

    摘要翻译: 本发明涉及猪皮肤样品作为皮肤模型的用途,特别是用于评估药理和美容效果。

    Antimicrobially active compounds for treating bad breath
    6.
    发明申请
    Antimicrobially active compounds for treating bad breath 审中-公开
    用于治疗口臭的抗微生物活性化合物

    公开(公告)号:US20080008660A1

    公开(公告)日:2008-01-10

    申请号:US11812085

    申请日:2007-06-14

    IPC分类号: A61K8/30 A61K31/16 A61Q11/00

    CPC分类号: A61K31/16 A61K8/42 A61Q11/00

    摘要: The invention relates primarily to specific uses of a compound of the Formula 1 or of mixtures of two or more different compounds of the Formula 1, in particular for producing an antimicrobially acting agent and agent against bad breath, as well as the corresponding production methods. In addition the invention relates to specific products, in particular oral hygiene products, comprising or consisting of a compound of the Formula 1 or of a mixture of two or more different compounds of the Formula 1 wherein the radicals of the compound of the Formula 1 or of each compound of the Formula 1 in the mixture are as defined in the preceding description.

    摘要翻译: 本发明主要涉及式1化合物或两种或多种不同式1化合物的混合物的具体用途,特别是用于生产抗微生物作用剂和抗口臭药物以及相应的生产方法。 此外,本发明涉及特定的产品,特别是口服卫生产品,其包含式I化合物或由式1的两种或更多种不同化合物的混合物组成或由其组成,其中式1化合物或 的混合物中式1的每种化合物如前述描述中所定义。