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    Balloon catheter and method of manufacture
    2.
    发明授权
    Balloon catheter and method of manufacture 失效
    球囊导管及制造方法

    公开(公告)号：US06554795B2

    公开(公告)日：2003-04-29

    申请号：US09026225

    申请日：1998-02-19

    申请人： Celso J. Bagaoisan ,  Ketan P. Muni ,  Hung V. Ha ,  Sivette Lam ,  Gholam-Reza Zadno-Azizi ,  Mukund R. Patel

    发明人： Celso J. Bagaoisan ,  Ketan P. Muni ,  Hung V. Ha ,  Sivette Lam ,  Gholam-Reza Zadno-Azizi ,  Mukund R. Patel

    IPC分类号： A61M2900

    CPC分类号： A61M25/1029 ,  A61M25/0009 ,  A61M25/1034 ,  B29C55/04

    摘要： Disclosed herein is a compliant catheter balloon with an improved elastic response and reduced longitudinal expansion, and a method of forming the same. The balloon comprises a SEBS block copolymer, which is longitudinally pre-stretched during the balloon manufacture process. In order to control the working length of a balloon on a catheter, at least one adhesive stop is provided on the catheter which prevents adhesive from wicking into the working length of the balloon. Preferably, a pair of thermoset tubings with an outer diameter size close to the size of the inner diameter of the balloon are inserted on the distal portion of the catheter. After the proper placement of the balloon, the adhesive is applied at the balloon's proximal and distal ends. As the adhesive wicks to the balloon, the thermoset tubings will eventually stop the adhesive to prevent further wicking of adhesive into the balloon's working length. In another aspect of the present invention, there is provided a method of manufacturing a balloon catheter to improve centering of the balloon on the catheter. After a balloon tubing is stretched, the stretched tubing is clamped to a fixture and stabilized at about 100° C. for 15 minutes. This stabilization step ensures that a balloon mounted on a catheter will inflate in a uniform manner.

    摘要翻译： 本文公开了一种具有改进的弹性响应和减小的纵向膨胀的柔顺导管气囊及其形成方法。 气球包含SEBS嵌段共聚物，其在球囊制造过程中被纵向预拉伸。 为了控制导管上的气球的工作长度，在导管上提供至少一个粘合阻挡件，其防止粘合剂吸入气球的工作长度。 优选地，具有接近球囊内径尺寸的外径尺寸的一对热固管插入导管的远端部分。 在适当放置气囊之后，将粘合剂施加在气囊的近端和远端。 当粘合剂吸入气球时，热固性管将最终停止粘合剂，以防止粘合剂进一步吸入气囊的工作长度。 在本发明的另一方面，提供一种制造球囊导管以改善球囊在导管上的对中的方法。 在气囊管被拉伸之后，将拉伸的管道夹紧到夹具上并在约100℃下稳定15分钟。 该稳定步骤确保安装在导管上的气囊将以均匀的方式充气。

    Method for containing and removing occlusions in the carotid arteries
    6.
    发明授权
    Method for containing and removing occlusions in the carotid arteries 失效
    颈动脉内容纳和去除闭塞的方法

    公开(公告)号：US06790204B2

    公开(公告)日：2004-09-14

    申请号：US10419912

    申请日：2003-04-15

    申请人： Gholam-Reza Zadno-Azizi ,  Mukund R. Patel ,  Ketan P. Muni ,  Celso J. Bagaosian ,  Hung V. Ha

    发明人： Gholam-Reza Zadno-Azizi ,  Mukund R. Patel ,  Ketan P. Muni ,  Celso J. Bagaosian ,  Hung V. Ha

    IPC分类号： A61M3100

    CPC分类号： A61M25/008 ,  A61B17/22 ,  A61B2017/22067 ,  A61B2017/22084 ,  A61B2217/005 ,  A61M25/0071 ,  A61M25/1011 ,  A61M2025/0081 ,  A61M2025/0183 ,  A61M2025/1052 ,  A61M2210/0693

    摘要： A method for the treatment of a stenosis or an occlusion in a blood vessel is disclosed in which a main catheter is first delivered to a site proximal to the occlusion. The main catheter may include an occlusive device at its distal end. An inner catheter or elongate member (e.g., a guidewire) having an occlusive device at its distal end is delivered to the site of the occlusion, and the occlusive device is activated at a site distal to the occlusion. A therapy catheter is then introduced to treat the occlusion. Next, a catheter is delivered just proximal to the occlusive device, and this catheter is used to aspirate and/or irrigate the area removing particles and debris. The aspiration and irrigation steps are preferably repeated until the particles and debris are removed. Perfusion may be performed by using a perfusion-filter distal of the lesion to be treated or a hypotube which extends beyond the occlusive device attached to the guidewire. The present invention provides for a minimally invasive procedure which can be performed quickly and efficiently, with reduced risks to the patient.

    摘要翻译： 公开了一种用于治疗血管狭窄或闭塞的方法，其中主导管首先被输送到接近闭塞的部位。 主导管可以在其远端处包括闭塞装置。 在其远端具有闭塞装置的内导管或细长构件（例如，导丝）被输送到闭塞部位，并且闭塞装置在远端闭塞位置被激活。 然后引入治疗导管以治疗闭塞。 接下来，将导管刚好靠近闭塞装置输送，并且该导管用于抽吸和/或冲洗除去颗粒和碎屑的区域。 优选重复抽吸和冲洗步骤，直到除去颗粒和碎屑。 灌注可以通过使用待治疗的病变的远侧的灌注过滤器或延伸超过连接到导丝线的闭塞装置的海波管来进行。 本发明提供了可以快速有效地执行并降低患者风险的微创手术。

    Aspiration catheter
    9.
    发明授权
    Aspiration catheter 失效
    吸气导管

    公开(公告)号：US06849068B1

    公开(公告)日：2005-02-01

    申请号：US09454522

    申请日：1999-12-06

    申请人： Celso J. Bagaoisan ,  Hung V. Ha ,  Mukund R. Patel ,  Sivette Lam

    发明人： Celso J. Bagaoisan ,  Hung V. Ha ,  Mukund R. Patel ,  Sivette Lam

    IPC分类号： A61F2/958 ,  A61M25/00

    CPC分类号： A61M25/1011 ,  A61M2025/1015 ,  A61M2025/1052 ,  A61M2025/109 ,  A61M2025/1093

    摘要： Aspiration catheters suitable for use in the treatment of an occlusion in a blood vessel are disclosed. These catheters are especially useful in the removal of occlusions from saphenous vein grafts, the coronary and carotid arteries, arteries above the aortic arch and even smaller vessels. The catheters of the present invention are provided in either over-the-wire or in single operator form. Radiopaque markers are preferably incorporated into distal ends of the catheters to facilitate their positioning within the body. The catheters are provided with varying flexibility along the length of the shaft, such that they are soft and flexible enough to be navigated through the vasculature of a patient without causing damage, but are stiff enough to sustain the axial push required to position the catheter properly and to sustain the aspiration pressures.

    摘要翻译： 公开了适合用于治疗血管闭塞的吸引导管。 这些导管特别适用于从隐静脉移植物，冠状动脉和颈动脉，主动脉弓上方的动脉以及更小的血管中去除闭塞。 本发明的导管以线上或单个操作者形式提供。 不透射线标记物优选并入导管的远端，以便于它们在体内的定位。 导管沿着轴的长度设置有不同的柔性，使得它们柔软且足够灵活，以便穿过患者的脉管系统而不造成损伤，但足够坚硬以维持正确定位导管所需的轴向推动 并维持吸引压力。