公开(公告)号：US20180179191A1

公开(公告)日：2018-06-28

申请号：US15809296

申请日：2017-11-10

Applicant: Gilead Sciences, Inc.

Inventor： Jinyu Shen ,  Mustapha St. Jules ,  David Sperandio ,  Sankar Mohan

IPC: C07D403/14 ,  C07D235/08 ,  C07D213/30 ,  C07D261/08 ,  C07B37/04 ,  C07B37/10

CPC classification number: C07D403/14 ,  C07B37/04 ,  C07B37/10 ,  C07D213/30 ,  C07D235/08 ,  C07D261/08 ,  C07D413/04 ,  C07D413/14

Abstract: The present disclosure provides processes for the preparation of a compound of formula I: or a salt or co-crystal thereof, that modulates the activity of bromodomain-containing proteins. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.