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公开(公告)号：US07207969B2
公开(公告)日：2007-04-24
申请号：US10309338
申请日：2002-12-02
IPC分类号： A61M37/00
CPC分类号： A61B17/00491 , A61B2017/00495 , A61J1/201 , A61J1/2013 , A61J1/2058 , A61J1/2096 , A61M5/1782
摘要： A filling device and method, particularly for two-component sealants such as fibrin sealants, which enables two fluids to be separately and directly filled to the reservoirs of a dual syringe fluid applicator from two storage containers, which can be standardized, sealed, sterilized bottles. The device has a connector which engages with the fluid applicator, is keyed to orient the applicator's fluid reservoirs in a predetermined manner and holds the containers in side-by-side alignment with the applicator. Two fluid conduits whose downward ends may be pointed to pierce seals on the bottles, extend between the applicator and the bottles and can each have a transverse reach to accommodate the girth of the bottles. The bottles may be tilted by the device to enable the conduits to draw maximal fluid from a lowermost point of the bottle. Tilting can be effected by a downward movement of the device supporting the applicator which movement can introduce the fluid conduits into the bottles. A shroud can enclose and seal the bottles and permit the apparatus complete with fluid applicator to be introduced into a sterile environment. Additionally embodiments for use with a single vial are also disclosed.
摘要翻译： 一种填充装置和方法，特别是用于诸如纤维蛋白密封剂的双组分密封剂，其使得两个流体能够从两个储存容器分开并直接填充到双注射器流体给药器的储存器中，这两个储存容器可以是标准化的密封灭菌瓶 。 该装置具有与流体施用器接合的连接器，用于以预定的方式定位施用器的流体储存器，并且将容器与施加器并排地对准。 两个流体管道，其下端可以指向刺穿瓶子上的密封件，在施用器和瓶子之间延伸，并且每个可以具有横向到达以适应瓶子的周长。 瓶子可以被装置倾斜，以使管道从瓶的最低点吸取最大流体。 倾斜可以通过支撑施加器的装置的向下运动来实现，该运动可以将流体导管引入瓶中。 护罩可以封闭并密封瓶子，并允许将流体施用器完成的装置引入无菌环境中。 还公开了与单个小瓶一起使用的另外的实施例。
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公开(公告)号：US06488650B1
公开(公告)日：2002-12-03
申请号：US09456728
申请日：1999-12-08
IPC分类号： A61M3700
CPC分类号： A61B17/00491 , A61B2017/00495 , A61J1/201 , A61J1/2013 , A61J1/2058 , A61J1/2096 , A61M5/1782
摘要： A filling device and method, particularly for two-component sealants such as fibrin sealants, which enables two fluids to be separately and directly filled to the reservoirs of a dual syringe fluid applicator from two storage containers, which can be standardized, sealed, sterilized bottles. The device has a connector which engages with the fluid applicator, is keyed to orient the applicator's fluid reservoirs in a predetermined manner and holds the containers in side-by-side alignment with the applicator. Two fluid conduits whose downward ends may be pointed to pierce seals on the bottles, extend between the applicator and the bottles and can each have a transverse reach to accommodate the girth of the bottles. The bottles may be tilted by the device to enable the conduits to draw maximal fluid from a lowermost point of the bottle. Tilting can be effected by a downward movement of the device supporting the applicator which movement can introduce the fluid conduits into the bottles. A shroud can enclose and seal the bottles and permit the apparatus complete with fluid applicator to be introduced into a sterile environment. Additionally embodiments for use with a single vial are also disclosed.
摘要翻译： 一种填充装置和方法，特别是用于诸如纤维蛋白密封剂的双组分密封剂，其使得两个流体能够从两个储存容器分开并直接填充到双注射器流体给药器的储存器中，这两个储存容器可以是标准化的密封灭菌瓶 。 该装置具有与流体施用器接合的连接器，用于以预定的方式定位施用器的流体储存器，并且将容器与施加器并排地对准。 两个流体管道，其下端可以指向刺穿瓶子上的密封件，在施用器和瓶子之间延伸，并且每个可以具有横向到达以适应瓶子的周长。 瓶子可以被装置倾斜，以使管道从瓶的最低点吸取最大流体。 倾斜可以通过支撑施加器的装置的向下运动来实现，该运动可以将流体导管引入瓶中。 护罩可以封闭并密封瓶子，并允许将流体施用器完成的装置引入无菌环境中。 还公开了与单个小瓶一起使用的另外的实施例。
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公开(公告)号：US07081103B2
公开(公告)日：2006-07-25
申请号：US10287934
申请日：2002-11-04
IPC分类号： A61M37/00
CPC分类号： A61B17/00491 , A61B2017/00495 , A61J1/201 , A61J1/2013 , A61J1/2058 , A61J1/2096 , A61M5/1782
摘要： A filling device for connecting a dispensing instrument having multiple fluid reservoirs to multiple containers is disclosed. More particularly, the present invention discloses a connecting device capable of coupling the individual reservoirs of a dispensing instrument to multiple fluid containers. The apparatus includes a body, a collar extending from the body, a plurality of tubes in fluid communication with a plurality of inlet ports formed in the body, and a hood adapted to simultaneously receive a plurality of containers therein. The containers are positioned within the hood to allow the plurality of tubes to simultaneously and separately draw fluid from the fluid containers and transferring the material into the individual reservoirs of the dispensing instrument.
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公开(公告)号：US06475183B1
公开(公告)日：2002-11-05
申请号：US09307056
申请日：1999-05-07
IPC分类号： A61M3700
CPC分类号： A61B17/00491 , A61B2017/00495 , A61J1/201 , A61J1/2013 , A61J1/2058 , A61J1/2096 , A61M5/1782
摘要： A filling device for connecting a dispensing instrument having multiple fluid reservoirs to multiple containers is disclosed. More particularly, the present invention discloses a connecting device capable of coupling the individual reservoirs of a dispensing instrument to multiple fluid containers. The apparatus includes a body, a collar extending from the body, a plurality of tubes in fluid communication with a plurality of inlet ports formed in the body, and a hood adapted to simultaneously receive a plurality of containers therein. The containers are positioned within the hood to allow the plurality of tubes to simultaneously and separately draw fluid from the fluid containers and transferring the material into the individual reservoirs of the dispensing instrument.
摘要翻译： 公开了一种用于将具有多个流体储存器的分配装置连接到多个容器的填充装置。 更具体地，本发明公开了一种连接装置，其能够将分配仪器的各储存器连接到多个流体容器。 该装置包括主体，从主体延伸的轴环，与形成在主体中的多个入口端口流体连通的多个管，以及适于同时在其中容纳多个容器的罩。 容器位于罩内，以允许多个管同时并分别从流体容器中抽出流体并将材料转移到分配器具的各个储存器中。
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公开(公告)号：US06926695B2
公开(公告)日：2005-08-09
申请号：US10377248
申请日：2003-02-27
CPC分类号： A61B17/00491 , A61B2017/00495
摘要： A sealant applicator suitable for dispensing a coagulable sealant, for example a two-component fibrin sealant mixed in the applicator, employs impulse clearing to remove residual coagulated or coagulating material from the dispensing pathway and mixing chamber, if present. Impulses may be generated by manual application of a clearing member such as a plunger which can enter into the dispensing pathway to engage, dislodge and discharge residuals or can generate a gas impulse to impact the residuals to similar effect. A clearing valve having a clearing port can be operated by movement of the clearing member to provide access to the dispensing pathway.
摘要翻译： 适用于分配可凝结密封剂的密封剂施加剂，例如混合在施用器中的双组分纤维蛋白密封剂，采用冲洗清除，以从分配通道和混合室（如果存在）中除去残留的凝固或凝结材料。 可以通过手动施加诸如柱塞的清理构件来产生冲击，所述柱塞可以进入分配路径以接合，移除和排出残余物，或者可以产生气体冲击以冲击残余物以产生类似的效果。 具有清除口的清除阀可以通过清除构件的移动来操作，以提供对分配通路的通路。
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公开(公告)号：US06575940B1
公开(公告)日：2003-06-10
申请号：US09315702
申请日：1999-05-20
IPC分类号： A61M500
CPC分类号： A61B17/00491 , A61B2017/00495
摘要： A sealant applicator suitable for dispensing a coagulable sealant, for example a two-component fibrin sealant mixed in the applicator, employs impulse clearing to remove residual coagulated or coagulating material from the dispensing pathway and mixing chamber, if present. Impulses may be generated by manual application of a clearing member such as a plunger which can enter into the dispensing pathway to engage, dislodge and discharge residuals or can generate a gas impulse to impact the residuals to similar effect. A clearing valve having a clearing port can be operated by movement of the clearing member to provide access to the dispensing pathway.
摘要翻译： 适用于分配可凝结密封剂的密封剂施加剂，例如混合在施用器中的双组分纤维蛋白密封剂，采用冲洗清除，以从分配通道和混合室（如果存在）中除去残留的凝固或凝结材料。 可以通过手动施加诸如柱塞的清理构件来产生冲击，所述柱塞可以进入分配路径以接合，移除和排出残余物，或者可以产生气体冲击以冲击残余物以产生类似的效果。 具有清除口的清除阀可以通过清除构件的移动来操作，以提供对分配通路的通路。
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公开(公告)号：US06921380B1
公开(公告)日：2005-07-26
申请号：US09408091
申请日：1999-09-29
CPC分类号： A61M37/00 , A61M2202/0425 , A61M2202/0449
摘要： A multi-component sealant applicator comprises a dual catheter for delivering sealant. Each catheter communicates with one of a pair of fluid sealant agent sources and comprises a mixing volume within the dual catheter for mixing multiple components of a multi-component sealant prior to discharge from a distal end of the catheter and a clearing system to clear undesired material from the mixing volume or the vicinity of the mixing volume, wherein one catheter is mounted for longitudinal movement within the other and the inner catheter is usable as a plunger to remove clogs. The catheter may comprise a reciprocal drive mechanism proximally coupled with the dual catheter to move one catheter longitudinally with respect to the other. The drive mechanism may comprise a ratchet and pawl.
摘要翻译： 多组分密封剂涂布器包括用于输送密封剂的双重导管。 每个导管与一对流体密封剂源中的一个连通，并且包括双重导管内的混合体积，用于在从导管的远端排出之前混合多部件密封剂的多个部件，并且清除系统以清除不需要的材料 从混合体积或混合体积附近，其中一个导管安装成在另一个内部纵向移动，并且内导管可用作柱塞以除去堵塞物。 导管可以包括与双导管近端耦合的往复驱动机构，以相对于另一个纵向移动一根导管。 驱动机构可以包括棘轮和棘爪。
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公开(公告)号：US06733472B1
公开(公告)日：2004-05-11
申请号：US09375755
申请日：1999-08-18
IPC分类号： A61M100
CPC分类号： B05C17/00516 , A61B17/00491 , A61B2017/00115 , A61B2017/00495 , A61M1/0043 , A61M1/0047 , A61M1/0064 , B05B7/0408 , B05C17/00553 , B05C17/0146 , Y10T137/7504 , Y10T137/86815
摘要： Multipurpose fluid applicators and applicator tips, particularly suitable for surgical purposes, are disclosed. The applicators and applicator tips are specifically designed for dispensing various combinations of sterile pressurized gas, suction, irrigation and sealant agents, including a mixed liquid sealant agent. Preferred embodiments employ a dual-acting valve selectively to control the flow of gas or suction which valve is capable of simultaneously varying flow from a source and the venting of that flow to atmosphere.
摘要翻译： 公开了多用途流体施加器和施用器尖端，特别适用于外科手术。 施用器和施用器尖端被专门设计用于分配无菌加压气体，抽吸，冲洗和密封剂的各种组合，包括混合液体密封剂。 优选实施例选择性地使用双作用阀来控制气体或抽吸的流动，该阀能够同时改变来自源的流动并将该流量排放到大气中。
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公开(公告)号：US09844461B2
公开(公告)日：2017-12-19
申请号：US13013603
申请日：2011-01-25
CPC分类号： A61F7/02 , A61F2007/0056 , A61F2007/0096 , A61F2007/029 , A61F2007/0292
摘要： Home-use applicators for non-invasively removing heat from subcutaneous, lipid-rich cells via phase change coolants, and associated devices, systems and methods. A device in accordance with a particular embodiment includes an applicator releasably positionable in thermal communication with human skin, and a coolant vessel having a coolant. The device further includes a heat transfer conduit operatively coupled to the applicator and housing a heat transfer fluid that is isolated from fluid contact with the coolant. A heat exchanger is operatively coupled between the coolant vessel and the heat transfer conduit to transfer heat between the heat transfer fluid and the coolant, and a fluid driver is operatively coupled to the heat transfer conduit to direct the heat transfer fluid between the applicator and the heat exchanger.
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公开(公告)号：US06432084B1
公开(公告)日：2002-08-13
申请号：US09566452
申请日：2000-05-08
IPC分类号： A61M100
CPC分类号： A61M11/02 , A61M35/003 , A61M2202/0449 , B05B1/267 , B05B7/066
摘要： A spray applicator particularly suited to needs of surgeons for dispensing a multi-component fluid, for example fibrin and thrombin components of a tissue adhesive. The spray applicator having a spray nozzle, a liquid dispensing aperture, a spray plate to be impacted by the liquid dispensed and a gas nozzle to provide a stream of carrier gas to carry the dispensed liquid away from the spray plate to form a spray.
摘要翻译： 特别适用于外科医生用于分配多组分流体（例如组织粘合剂的纤维蛋白和凝血酶组分）的喷雾施用器。 喷雾器具有喷嘴，液体分配孔，待分配的液体冲击的喷射板和气体喷嘴，以提供载气流以将分配的液体远离喷雾板以形成喷雾。
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