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    Organic/inorganic nanocomposites obtained by extrusion
    1.
    发明申请
    Organic/inorganic nanocomposites obtained by extrusion 审中-公开
    通过挤出获得的有机/无机纳米复合材料

    公开(公告)号：US20050027040A1

    公开(公告)日：2005-02-03

    申请号：US10478979

    申请日：2002-05-31

    申请人： Gordon Nelson ,  Feng Yang

    发明人： Gordon Nelson ,  Feng Yang

    IPC分类号： C08J3/21 ,  C08J3/22 ,  C08K3/18 ,  C08K3/34 ,  C08K9/00 ,  C08K9/04

    CPC分类号： C08K9/04 ,  B82Y30/00 ,  C08J3/212 ,  C08J3/226 ,  C08J5/005 ,  C08J2325/06 ,  C08J2333/12 ,  C08J2425/00 ,  C08J2433/00

    摘要： Organic/inorganic nanocomposites and methods for their preparation are disclosed. In one embodiment, the method comprises the steps of providing an organic/inorganic concentrate and processing the concentrate with a polymer resin. In a preferred embodiment the organic/inorganic concentrate and polymer resin are processed by extrusion using a single-screw extruder. In another embodiment, the method further comprises surface modifying an inorganic additive, mixing the modified additive with a polymer solution to produce an organic/inorganic solution, and removing solvent from the organic/inorganic solution to produce the organic/inorganic concentrate. Processing of the organic/inorganic concentrate with a polymer resin produces a homogeneous nanocomposite with superior mechanical and thermal properties.

    摘要翻译： 公开了有机/无机纳米复合材料及其制备方法。 在一个实施方案中，该方法包括提供有机/无机浓缩物并用聚合物树脂处理浓缩物的步骤。 在优选的实施方案中，使用单螺杆挤出机挤出加工有机/无机浓缩物和聚合物树脂。 在另一个实施方案中，该方法还包括对无机添加剂进行表面改性，将改性添加剂与聚合物溶液混合以产生有机/无机溶液，以及从有机/无机溶液中除去溶剂以产生有机/无机浓缩物。 用聚合物树脂处理有机/无机浓缩物产生具有优异机械和热性能的均匀的纳米复合材料。

    Palatable micro-capsules
    5.
    发明申请
    Palatable micro-capsules 审中-公开
    可口的微胶囊

    公开(公告)号：US20060165614A1

    公开(公告)日：2006-07-27

    申请号：US10534948

    申请日：2003-11-14

    申请人： Gordon Nelson ,  Stephen Duckham ,  Andrew Round

    发明人： Gordon Nelson ,  Stephen Duckham ,  Andrew Round

    IPC分类号： A61K8/96 ,  A61K9/50

    CPC分类号： A61K9/5068

    摘要： A formulation comprising at least one active or at least one ingredient, and a plurality of micro-capsules formed from a plurality of micro-organisms and having at least one flavouring encapsulated and passively retained within said micro-capsules, said flavouring not being a natural constituent of said micro-organisms, said micro-capsules having: (a) an at least substantially intact cell wall; and (b) an intact cell membrane; wherein said at least one active or said at least one ingredient is foul-tasting and said at least one flavouring masks, disguises or neutralises the foul-taste of said at least one active or said at least one ingredient, preventing a patient to whom said formulation is orally administered from tasting said foul-tasting active, or causing the flavour of said foul-tasting at least one active or ingredient to be reduced such that it is more palatable. Also disclosed are methods of manufacturing said formulations.

    摘要翻译： 包含至少一种活性成分和至少一种成分的制剂以及由多种微生物形成并具有至少一种包封并被动地保留在所述微胶囊内的调味剂的微胶囊，所述调味剂不是天然的 所述微型胶囊具有：（a）至少基本完整的细胞壁; 和（b）完整的细胞膜; 其中所述至少一种活性物质或所述至少一种成分是不合格的，并且所述至少一种调味剂掩盖，伪装或中和所述至少一种活性物质或所述至少一种成分的污点，防止所述至少一种活性物质或所述至少一种成分 制剂通过品尝所述污点活性物质口服施用，或引起所述污迹的风味至少一种活性成分或成分被还原，使得其更可口。 还公开了制造所述制剂的方法。

    Methods for quantitative analysis by tandem mass spectrometry
    6.
    发明申请
    Methods for quantitative analysis by tandem mass spectrometry 有权
    串联质谱定量分析方法

    公开(公告)号：US20050165560A1

    公开(公告)日：2005-07-28

    申请号：US10508068

    申请日：2003-03-14

    申请人： Mark Kushnir ,  Alan Rockwood ,  Gordon Nelson

    发明人： Mark Kushnir ,  Alan Rockwood ,  Gordon Nelson

    IPC分类号： G01N33/487 ,  G06F19/00 ,  H01J49/16 ,  H01J49/40

    CPC分类号： H01J49/0009 ,  H01J49/004 ,  Y10T436/11

    摘要： The present invention provides methods for high throughput analysis of analytes in complex mixtures for unresolved chromatographic peaks including specific embodiment for summing intensities for each mass transition of interest over a selected chromatographic peak (50) to generate a signal corresponding to total intensity for each transition (55, 60). The intensities are deconvoluted into intensities of individual analytes (65, 70), based on branching ratios acquired from authentic standards, and a comparison to calibration curve is performed to obtain a quantitative concentration measurement of a particular analyte in a sample.

    摘要翻译： 本发明提供了用于未分辨色谱峰的复杂混合物中分析物的高通量分析的方法，包括用于在所选择的色谱峰（50）上对每个感兴趣的质量转换求和强度的特定实施方案，以产生对应于每个转变的总强度的信号 55，60）。 基于从真实标准获得的分支比例，将强度解卷积成单个分析物（65,70）的强度，并且进行与校准曲线的比较以获得样品中特定分析物的定量浓度测量。

    Centrifugal swing arm spray processor
    9.
    发明授权
    Centrifugal swing arm spray processor 有权
    离心摆臂喷雾处理器

    公开(公告)号：US07144459B2

    公开(公告)日：2006-12-05

    申请号：US10200072

    申请日：2002-07-19

    申请人： Raymon Thompson ,  Gordon Nelson

    发明人： Raymon Thompson ,  Gordon Nelson

    IPC分类号： B05B3/00

    CPC分类号： H01L21/6708 ,  H01L21/67051

    摘要： A machine for processing a flat workpiece or wafer has a head, which spins the wafer between upper and lower weirs in a base. The head is spaced apart from the base by an air gap. A vacuum source attached to an exhaust opening in the base draw air through the air gap, to reduce or eliminate movement of process chemicals into the head. Corrosion of head components by process chemicals is reduced. The disadvantages of having a mechanical seal between the base and the head are also eliminated.

    摘要翻译： 用于处理平坦工件或晶片的机器具有头部，其在基部中的上堰和下堰之间旋转晶片。 头部与基座间隔开一个气隙。 附着在底座中的排气口的真空源通过气隙吸引空气，以减少或消除过程化学物质进入头部的运动。 头部组分由工艺化学品腐蚀减少。 也消除了在基座和头部之间具有机械密封的缺点。

    Targeted delivery
    10.
    发明申请
    Targeted delivery 审中-公开
    有针对性的交货

    公开(公告)号：US20060127489A1

    公开(公告)日：2006-06-15

    申请号：US10532368

    申请日：2003-10-23

    申请人： Michael Crothers ,  Gordon Nelson

    发明人： Michael Crothers ,  Gordon Nelson

    IPC分类号： A61K9/50 ,  A61K9/16 ,  C12P21/06

    CPC分类号： A61K9/5068

    摘要： An encapsulated product comprises a plurality of micro-capsules formed from a plurality of micro-organisms and having a lipophilic active encapsulated and passively retained within said micro-capsules. The lipophilic active is not being a natural constituent of the micro-organisms, and the micro-capsules has: (a) an at least substantially intact cell wall, and (b) an intact cell membrane. The micro-capsules are formulated to target delivery of the micro-capsules and the lipophilic active to at least one desired mucous membrane.

    摘要翻译： 包封的产品包括由多个微生物形成的多个微胶囊，并且具有包封并被动地保持在所述微胶囊内的亲脂性活性物质。 亲脂性活性物质不是微生物的天然成分，微胶囊具有：（a）至少基本上完整的细胞壁，和（b）完整的细胞膜。 配制微胶囊以将微胶囊和亲脂性活性物质目标递送至至少一种所需的粘膜。