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15 条记录 (耗时 0.019 秒)

    Stabilization of (hydrocarbylthio) aromatic amines against odor formation
    2.
    发明授权
    Stabilization of (hydrocarbylthio) aromatic amines against odor formation 失效
    （烃基硫代）芳族胺对气味形成的稳定化

    公开(公告)号：US5840984A

    公开(公告)日：1998-11-24

    申请号：US880547

    申请日：1997-06-23

    申请人： Gregory H. Lambeth ,  Paul L. Wiggins ,  William R. Brown

    发明人： Gregory H. Lambeth ,  Paul L. Wiggins ,  William R. Brown

    IPC分类号： C07C323/36 ,  C07C319/26 ,  C07C373/36

    CPC分类号： C07C319/26

    摘要： Odor formation during storage of (hydrocarbylthio)aromatic amines due to formation and release of odoriferous sulfur-containing species such as dihydrocarbyldisulfides, is suppressed. To accomplish this, a small amount of N,N-dihydrocarbylhydroxylamine odor-inhibitor (e.g., N,N-diethylhydroxylamine) is blended with the (hydrocarbylthio)aromatic amine. This enables products such as a mixture of 3,5-di(methylthio)-2,4-diaminotoluene and 3,5-di(methylthio)-2,6-diaminotoluene) to be stored for long periods of time with significantly reduced formation and release of odoriferous sulfur-containing species.

    摘要翻译： 抑制由于含有臭味的含硫物质如二烃基二硫化物的形成和释放而在（烃硫基）芳族胺储存期间的气味形成。 为了实现这一点，将少量的N，N-二烃基羟胺气味抑制剂（例如N，N-二乙基羟胺）与（烃硫基）芳族胺共混。 这使得诸如3,5-二（甲硫基）-2,4-二氨基甲苯和3,5-二（甲硫基）-2,6-二氨基甲苯的混合物的产物能够长时间储存​​，同时显着减少了形成 并释放有气味的含硫物质。

    Aromatic amine curatives and their use
    3.
    发明授权
    Aromatic amine curatives and their use 失效
    芳香胺固化剂及其用途

    公开(公告)号：US06509434B1

    公开(公告)日：2003-01-21

    申请号：US09528837

    申请日：2000-03-20

    申请人： William R. Brown ,  John C. Prindle, Jr. ,  Gregory H. Lambeth

    发明人： William R. Brown ,  John C. Prindle, Jr. ,  Gregory H. Lambeth

    IPC分类号： C08G1832

    CPC分类号： C08G18/3868 ,  C08G18/10

    摘要： Mixtures of isomeric alkylthiated mononuclear aromatic amines comprising in the range of about 30 to about 70 mole percent of (i) at least one 3,5-di(alkyl-thio)-2,6-diamino-1-alkylbenzene and in the range of about 30 to about 70 mole percent of at least one 3,5-di(alkylthio)-2,4-diamino-1-alkylbenzene, such mixture containing at least about 90 mole percent of (i) and (ii), and optionally containing up to 10 mole percent of one or more isomers of (i) and/or (ii). An alkyl group may be present as a substituent in lieu of a hydrogen atom in the remaining ring position. These mixtures are useful as curatives or extenders in processes for making polyurethanes, polyurethane-ureas, and polyureas.

    摘要翻译： 异构烷基化的单核芳香族胺的混合物，其包含（i）至少一种3,5-二（烷基 - 硫代）-2,6-二氨基-1-烷基苯的约30至约70摩尔％范围内， 约30至约70摩尔％的至少一种3,5-二（烷硫基）-2,4-二氨基-1-烷基苯，该混合物含有至少约90摩尔％的（ⅰ）和（ⅱ），和 任选地含有至多10摩尔％的（i）和/或（ii）的一种或多种异构体。 烷基可以作为取代基代替其余环位置上的氢原子。 这些混合物可用作制备聚氨酯，聚氨酯 - 脲和聚脲的方法中的固化剂或增量剂。

    Highly Concentrated Pourable Aqueous Solutions Of Potassium Ibuprofen, Their Preparation And Their Use
    7.
    发明申请
    Highly Concentrated Pourable Aqueous Solutions Of Potassium Ibuprofen, Their Preparation And Their Use 审中-公开
    高浓度易挥发的布洛芬钾水溶液及其制备及其应用

    公开(公告)号：US20080269334A1

    公开(公告)日：2008-10-30

    申请号：US12066371

    申请日：2006-09-15

    申请人： Partick C. Hu ,  Gregory H. Lambeth ,  Arcelio J. Malcolm

    发明人： Partick C. Hu ,  Gregory H. Lambeth ,  Arcelio J. Malcolm

    IPC分类号： A61K31/192 ,  A61P29/00

    CPC分类号： A61K9/4858 ,  A61K31/19 ,  A61K47/10

    摘要： Concentrated pourable potassium ibuprofen liquid compositions, and preparation and uses thereof are described. They are composed of (i) at least 60 wt % of potassium ibuprofen in dissolved form; (ii) water; (iii) one or more polyethylene glycols, (iv) optionally up to 5 wt % of at least one C2-3 alkanol; and (v) optionally, ibuprofen in free acid form. The weight ratio of (ii):(iii) is at least 0.9:1. Compositions containing as much as 85.2 wt % of potassium ibuprofen in dissolved form have been successfully made. The highest level of potassium ibuprofen in dissolved form achieved in experiments reported in the presently-known prior art is but 24.2 wt %. The present compositions are suitable for use in the preparation of pharmaceutical products and various pharmaceutical dosage forms such as liquid-filled soft gelatin capsules, syrups, elixirs, suspensions; solid dosage forms such as tablets or caplets; and topically-applied products. such as lotions, creams or ointments.

    摘要翻译： 浓缩的可倾倒的布洛芬钾液体组合物及其制备和用途进行了描述。 它们由以下组成：（i）至少60重量％的溶解形式的布洛芬钾; （ii）水; （iii）一种或多种聚乙二醇，（iv）任选至多5重量％的至少一种C 2至3-3链烷醇; 和（v）任选地，游离酸形式的布洛芬。 （ii）：（iii）的重量比至少为0.9:1。 含有多达85.2重量％溶解形式的布洛芬钾的组合物已经成功地制成。 目前已知的现有技术报道的实验中获得的溶解形式的最高水平的布洛芬钾仅为24.2重量％。 本发明的组合物适用于制备药物产品和各种药物剂型，例如液体填充的软明胶胶囊，糖浆，酏剂，悬浮液; 固体剂型如片剂或片剂; 和局部应用产品。 如乳液，霜剂或软膏。