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1.
公开(公告)号:US20150056248A1
公开(公告)日:2015-02-26
申请号:US14464132
申请日:2014-08-20
申请人: Gregory HAIWICK , Marc Allan EICHMEYER , Luis Alejandro HERNANDEZ , Wesley Scott JOHNSON , Christine Margaret MUEHLENTHALER , Eric Martin VAUGHN
发明人: Gregory HAIWICK , Marc Allan EICHMEYER , Luis Alejandro HERNANDEZ , Wesley Scott JOHNSON , Christine Margaret MUEHLENTHALER , Eric Martin VAUGHN
IPC分类号: A61K39/12
CPC分类号: A61K39/12 , A61K2039/5252 , A61K2039/5256 , A61K2039/55 , A61K2039/552 , A61K2039/55516 , A61K2039/55566 , A61K2039/58 , C12N7/00 , C12N2710/14043 , C12N2750/10034
摘要: Vaccination methods to control PCV2 infection with different PCV2 subtypes are disclosed. Specifically, a PCV2 subtype b (PCV2b) ORF2 proteins or immunogenic compositions comprising a PCV2b ORF2 protein are used in a method for the treatment or prevention of an infection with PCV2 of a different subtype, the reduction, prevention or treatment of clinical signs caused by an infection with PCV2 of a different subtype, or the prevention or treatment of a disease caused by an infection with PCV2 of a different subtype.
摘要翻译: 公开了用不同PCV2亚型控制PCV2感染的疫苗接种方法。 具体地说,将PCV2亚型b(PCV2b)ORF2蛋白质或包含PCV2b ORF2蛋白质的免疫原性组合物用于治疗或预防不同亚型的PCV2感染的方法,减少,预防或治疗由 不同亚型的PCV2的感染,或预防或治疗由不同亚型的PCV2的感染引起的疾病。
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公开(公告)号:US20140248603A1
公开(公告)日:2014-09-04
申请号:US14194380
申请日:2014-02-28
申请人: Marc Allan EICHMEYER , Michael B. ROOF , Merrill Lynn SCHAEFFER , Eric Martin VAUGHN , Kun YANG , Jeremy Richard RUSH , Daniel John MURFIN
发明人: Marc Allan EICHMEYER , Michael B. ROOF , Merrill Lynn SCHAEFFER , Eric Martin VAUGHN , Kun YANG , Jeremy Richard RUSH , Daniel John MURFIN
IPC分类号: C12Q1/37 , G01N33/569 , C07K14/005 , C07K7/08 , C07K7/06
CPC分类号: C12Q1/37 , C07K7/06 , C07K7/08 , C07K14/001 , C07K14/005 , G01N33/56983 , G01N33/6848 , G01N2333/01
摘要: The invention provides methods and mass-labeled peptides for use in said methods for quantifying the presence of a one or more viral proteins in a sample of a preparation containing agents which bind to said viral protein, using mass-spectroscopic analyses of the sample and standards containing known amounts of labeled and unlabeled signature peptides, in particular wherein said viral proteins are antigens in a vaccine for porcine circovirus.
摘要翻译: 本发明提供了用于所述方法的方法和质量标记的肽,用于定量含有与所述病毒蛋白结合的试剂的制剂的样品中一种或多种病毒蛋白的存在,使用样品和标准品的质谱分析 含有已知量的标记和未标记的特征肽,特别是其中所述病毒蛋白是猪圆环病毒疫苗中的抗原。
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