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公开(公告)号:US20100056979A1
公开(公告)日:2010-03-04
申请号:US12618437
申请日:2009-11-13
申请人: Gregory Smedley , David Haffner , Hosheng Tu , Morteza Gharib
发明人: Gregory Smedley , David Haffner , Hosheng Tu , Morteza Gharib
IPC分类号: A61M1/00
CPC分类号: A61F9/00781 , A61F9/0017
摘要: A trabecular pump is implantable in the eye to reduce intraocular pressure. The pump drains aqueous humor from the anterior chamber into outflow pathways, such as Schlemm's canal. A feedback system includes an intraocular pump and a pressure sensor in communication with the pump, for regulating intraocular pressure.
摘要翻译: 小梁泵可植入眼睛以降低眼内压。 泵将房水从前房排出到流出路径,如施勒姆运河。 反馈系统包括与泵连通的眼内泵和压力传感器,用于调节眼内压。
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公开(公告)号:US08348877B2
公开(公告)日:2013-01-08
申请号:US12772889
申请日:2010-05-03
申请人: Hosheng Tu , Barbara Niksch , David Haffner , Gregory Smedley , Olav B Bergheim , Morteza Gharib
发明人: Hosheng Tu , Barbara Niksch , David Haffner , Gregory Smedley , Olav B Bergheim , Morteza Gharib
IPC分类号: A61M19/00
CPC分类号: A61F9/00781 , A61F9/0017 , A61F2250/0067 , A61L27/54 , A61L2300/258 , A61L2300/41 , A61L2300/414 , A61L2300/416 , A61L2300/42 , A61L2430/16 , A61M27/002
摘要: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye such that at least a distal end of the implant is temporarily in the anterior chamber. The implant is implanted into eye tissue adjacent the anterior chamber. A therapeutic agent is eluted from the implant into at least one of the anterior chamber, a physiologic outflow pathway of the eye, and a space adjacent a choroid of the eye. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension. The therapeutic agent can be contained within the implant or coated on the implant.
摘要翻译: 提供了用于治疗眼部疾病的植入物和方法。 一种方法包括将植入物引入眼睛的前房,使得植入物的至少远端暂时位于前房中。 将植入物植入邻近前房的眼组织。 将治疗剂从植入物洗脱到前房中的至少一个,眼睛的生理流出路径和与眼睛的脉络膜相邻的空间。 治疗剂可以是抗增生剂,抗炎药或治疗青光眼或高眼压症的化合物。 治疗剂可以包含在植入物内或涂覆在植入物上。
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公开(公告)号:US20070010827A1
公开(公告)日:2007-01-11
申请号:US11455391
申请日:2006-06-19
申请人: Hosheng Tu , David Haffner , Gregory Smedley , Barbara Niksch , Morteza Gharib
发明人: Hosheng Tu , David Haffner , Gregory Smedley , Barbara Niksch , Morteza Gharib
IPC分类号: A61F11/00
CPC分类号: A61F9/00781 , A61M27/002
摘要: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
摘要翻译: 公开了用于治疗青光眼的手术方法和相关的医疗装置。 该方法包括小梁旁路手术,其涉及利用支架植入物绕过患病的小梁网。 支架植入物通过刺穿构件插入在小梁网中形成的开口中,该刺穿构件可滑动地前进通过支架植入物的内腔,用于支撑植入物插入。 支架植入物定位穿过小梁网,使得支架植入物的入口端暴露于眼睛的前房,并且出口端被定位在围绕小梁网的外表面的流体收集通道中,或直到 水静脉水平。
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公开(公告)号:US20060241749A1
公开(公告)日:2006-10-26
申请号:US11455598
申请日:2006-06-19
申请人: Hosheng Tu , David Haffner , Gregory Smedley , Barbara Niksch , Morteza Gharib
发明人: Hosheng Tu , David Haffner , Gregory Smedley , Barbara Niksch , Morteza Gharib
IPC分类号: A61F2/14
CPC分类号: A61F9/00781 , A61M27/002
摘要: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
摘要翻译: 公开了用于治疗青光眼的手术方法和相关的医疗装置。 该方法包括小梁旁路手术,其涉及利用支架植入物绕过患病的小梁网。 支架植入物通过刺穿构件插入在小梁网中形成的开口中,该刺穿构件可滑动地前进通过支架植入物的内腔,用于支撑植入物插入。 支架植入物定位穿过小梁网,使得支架植入物的入口端暴露于眼睛的前房,并且出口端被定位在围绕小梁网的外表面的流体收集通道中,或直到 水静脉水平。
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公开(公告)号:US20050277864A1
公开(公告)日:2005-12-15
申请号:US11126868
申请日:2005-05-11
申请人: David Haffner , Morteza Gharib , Hosheng Tu
发明人: David Haffner , Morteza Gharib , Hosheng Tu
CPC分类号: A61L27/56 , A61F9/00781 , A61L27/50 , A61L2430/16 , B01F5/0411
摘要: Methods and implants for treating glaucoma in an eye are described. The implant includes an inlet section configured to be positioned in the anterior chamber of the eye and an outlet section in fluid communication with the inlet section. The outlet section is configured to be positioned in Schlemm's canal of the eye. The implant comprises a hydrogel and is configured to conduct aqueous humor from the anterior chamber to Schlemm's canal.
摘要翻译: 描述了用于治疗眼睛中青光眼的方法和植入物。 植入物包括被配置为定位在眼睛的前房中的入口部分和与入口部分流体连通的出口部分。 出口部分被配置成位于眼睛的施莱姆的运河中。 植入物包括水凝胶并且构造成将房水从前房导入施莱姆氏管。
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公开(公告)号:US20070282245A1
公开(公告)日:2007-12-06
申请号:US11836118
申请日:2007-08-08
申请人: Hosheng Tu , David Haffner , Morteza Gharib
发明人: Hosheng Tu , David Haffner , Morteza Gharib
IPC分类号: A61M27/00
CPC分类号: A61F9/00781 , A61F9/0017 , A61F9/007 , A61F2009/00891 , A61F2250/0067 , A61K9/0051 , A61M27/002 , A61M2210/0612 , Y10S623/905
摘要: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involve bypassing diseased trabecular meshwork with the use of a seton implant. The seton implant is used to prevent a healing process known as filling in, which has a tendency to close surgically created openings in the trabecular meshwork. The surgical method and novel implant are addressed to the trabecular meshwork, which is a major site of resistance to outflow in glaucoma. In addition to bypassing the diseased trabecular meshwork at the level of the trabecular meshwork, existing outflow pathways are also used or restored. The seton implant is positioned through the trabecular meshwork so that an inlet end of the seton implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
摘要翻译: 公开了用于治疗青光眼的手术方法和相关的医疗装置。 该方法包括小梁旁路手术,其涉及利用植入物绕过患病的小梁网。 镶嵌植入物用于防止称为填充的愈合过程,其具有在小梁网中关闭手术产生的开口的趋势。 手术方法和新型植入物是针对小梁网,其是青光眼流出阻力的主要部位。 除了在小梁网的水平绕过患病的小梁网,还使用或恢复现有的流出路径。 镶嵌植入物定位穿过小梁网,使得植入植入物的入口端暴露于眼睛的前房,并且出口端定位在小梁网的大约外表面处的流体收集通道中,或直到 水静脉水平。
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公开(公告)号:US20050049578A1
公开(公告)日:2005-03-03
申请号:US10910962
申请日:2004-08-04
申请人: Hosheng Tu , David Haffner , Morteza Gharib , Denis Phares
发明人: Hosheng Tu , David Haffner , Morteza Gharib , Denis Phares
CPC分类号: A61F9/00781 , A61B3/16
摘要: A trabecular pump is implantable in the eye to reduce intraocular pressure. The pump drains aqueous humor from the anterior chamber into outflow pathways, such as Schlemm's canal. A feedback system includes the intraocular pump and a pressure sensor in communication with the pump, for regulating intraocular pressure.
摘要翻译: 小梁泵可植入眼睛以降低眼内压。 泵将房水从前房排出到流出路径,如施勒姆运河。 反馈系统包括眼内泵和与泵连通的压力传感器,用于调节眼内压。
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公开(公告)号:US20080015488A1
公开(公告)日:2008-01-17
申请号:US11860785
申请日:2007-09-25
申请人: Hosheng Tu , Gregory Smedley , Barbara Niksch , David Haffner
发明人: Hosheng Tu , Gregory Smedley , Barbara Niksch , David Haffner
IPC分类号: A61M1/00
CPC分类号: A61F2/16 , A61F9/00781 , A61K9/0048
摘要: The invention relates generally medical devices and methods for the treatment of glaucoma in an animal eye and, more particularly, to medical devices and methods for treating tissue of the trabecular meshwork and/or Schlemm's canal of the eye to restore or rejuvenate a portion or all of the normal physiological function of directing aqueous outflow for maintaining a normal intraocular pressure in the eye.
摘要翻译: 本发明一般涉及用于治疗动物眼睛中的青光眼的医疗装置和方法,更具体地,涉及用于治疗小梁网和/或眼睛的施莱姆氏管的组织以恢复或恢复一部分或全部的医疗装置和方法 引导水流出的正常生理功能,以维持眼中正常的眼内压。
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公开(公告)号:US20070276316A1
公开(公告)日:2007-11-29
申请号:US11836112
申请日:2007-08-08
申请人: David Haffner , Gregory Smedley , Hosheng Tu
发明人: David Haffner , Gregory Smedley , Hosheng Tu
IPC分类号: A61M1/00
CPC分类号: A61F9/00781
摘要: Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
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公开(公告)号:US20070276315A1
公开(公告)日:2007-11-29
申请号:US11836106
申请日:2007-08-08
申请人: David Haffner , Gregory Smedley , Hosheng Tu
发明人: David Haffner , Gregory Smedley , Hosheng Tu
IPC分类号: A61M1/00
CPC分类号: A61F9/00781
摘要: Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
摘要翻译: 公开了用于治疗青光眼的眼内支架和敷贴器。 支架构造成在眼前房和施乐姆氏管之间延伸,以增强从前房的水流出,以便降低眼内压。 支架可以具有用于将支架锚定到施乐姆运河中的特征,以及阻止施莱姆运河的墙壁关闭支架的出口。 施加器可以是可操纵的,以便使植入更容易。 此外,施用器可以被配置成保持多个支架,使得可以通过一个切口植入多个支架,而不会从串联注入之间的切口移除施加器。
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