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1.发明授权Latent protein C assays and their uses for diagnosis and/or prognosis in systemic inflammatory response syndromes 有权潜伏蛋白C测定及其在全身炎症反应综合征中的诊断和/或预后的用途公开(公告)号：US07655428B2
公开(公告)日：2010-02-02
申请号：US11614836
申请日：2006-12-21
IPC分类号： G01N21/00 , G01N21/64 , G01N21/75 , G01N21/76 , G01N25/18 , G01N33/00 , A61K39/00 , A61K39/395 , A61K39/44
CPC分类号： C07K16/36 , C07K16/40 , G01N33/573 , G01N33/6893 , G01N33/86 , G01N2333/96461 , G01N2800/26
摘要： The present invention relates to methods and compositions for measuring latent protein C in test samples, particularly patient samples. The methods and compositions described are sensitive for latent protein C, relative to activated protein C.
摘要翻译： 本发明涉及用于测量试验样品，特别是患者样品中潜伏蛋白C的方法和组合物。 所述方法和组合物相对于活化的蛋白C对潜伏蛋白C敏感。
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2.发明授权Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes 有权用于全身炎症反应综合征的诊断和/或预后的方法和组合物公开(公告)号：US08221995B2
公开(公告)日：2012-07-17
申请号：US12663841
申请日：2008-06-27
申请人： Seok-Won Lee , Kelline M. Rodems , David W. Oelschlager , Uday Kumar Veeramallu , Joseph A. Buechler , Paul H. McPherson
发明人： Seok-Won Lee , Kelline M. Rodems , David W. Oelschlager , Uday Kumar Veeramallu , Joseph A. Buechler , Paul H. McPherson
IPC分类号： G01N33/00
CPC分类号： G01N33/6893 , G01N2333/521 , G01N2800/26 , G01N2800/50 , G01N2800/56
摘要： The present invention relates to methods and compositions for diagnosing SIRS, sepsis, severe sepsis, septic shock, or MODS in a subject, or assigning a prognostic risk for one or more clinical outcomes for a subject suffering from SIRS, sepsis, severe sepsis, septic shock, or MODS, the method comprising performing an immunoassay for CCL23 splice variant.
摘要翻译： 本发明涉及用于诊断受试者的SIRS，败血症，严重败血症，败血性休克或MODS的方法和组合物，或为患有SIRS，败血症，严重败血症，败血症的受试者分配一种或多种临床结果的预后风险 休克或MODS，所述方法包括对CCL23剪接变体进行免疫测定。
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3.发明申请METHODS AND COMPOSITIONS FOR DIAGNOSIS AND/OR PROGNOSIS IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROMES 审中-公开用于系统性炎症反应综合征诊断和/或预防的方法和组合物公开(公告)号：US20090004755A1
公开(公告)日：2009-01-01
申请号：US11770608
申请日：2007-06-28
申请人： Seok-Won Lee , Kelline M. Rodems , David W. Oelschlager , Uday Kumar Veeramallu , Joseph A. Buechler , Paul H. McPherson
发明人： Seok-Won Lee , Kelline M. Rodems , David W. Oelschlager , Uday Kumar Veeramallu , Joseph A. Buechler , Paul H. McPherson
IPC分类号： G01N33/566
CPC分类号： G01N33/6893 , G01N2333/521 , G01N2800/50 , G01N2800/56
摘要： The present invention relates to methods and compositions for diagnosing SIRS, sepsis, severe sepsis, septic shock, or MODS in a subject, or assigning a prognostic risk for one or more clinical outcomes for a subject suffering from SIRS, sepsis, severe sepsis, septic shock, or MODS, the method comprising performing an immunoassay for CCL23 splice variant.
摘要翻译： 本发明涉及用于诊断受试者的SIRS，败血症，严重败血症，败血性休克或MODS的方法和组合物，或为患有SIRS，败血症，严重败血症，败血症的受试者分配一种或多种临床结果的预后风险 休克或MODS，所述方法包括对CCL23剪接变体进行免疫测定。
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