公开(公告)号：US20080007820A1

公开(公告)日：2008-01-10

申请号：US11806458

申请日：2007-05-31

Applicant: Gunter Moehler ,  Mirko Liedtke

Inventor： Gunter Moehler ,  Mirko Liedtke

IPC: G02B21/36 ,  H04L12/28

CPC classification number: H04L12/407 ,  G02B21/008 ,  G02B21/365 ,  H04L2012/40215

Abstract: Specimen laser-scanning microscope with rasterizing illumination and detector resources (resources), which rasterizes and scan detects a specimen. A real-time control device (device) performs synchronous reading-out with the rasterizing pixel cycle. A data port serially communicates with the device using a bidirectional high-speed data stream and with the resources via a serial, bidirectional high-speed data stream with a data conversion to/from parallel to serial. The high-speed data stream is made up of data packets with data bits and type bits and no additional header or protocol bits. The data bits contain data from/on the resources and the type bits code the type of data. Type information is stored in the resources as well as the device. The type information defines processing functions for data types coded by the type bits, and the resources and/or the device determine the data type using type bits and process data coded in the data bits.

Abstract translation: 具有光栅照明和检测器资源（资源）的样品激光扫描显微镜，其光栅化和扫描检测样品。 实时控制装置（装置）利用光栅化像素周期执行同步读出。 数据端口使用双向高速数据流和通过串行双向高速数据流与资源串行地与设备进行通信，数据转换到并行到串行数据转换。 高速数据流由具有数据位和类型位的数据分组组成，没有附加的报头或协议位。 数据位包含来自资源的数据，类型位代码数据类型。 类型信息存储在资源以及设备中。 类型信息定义由类型位编码的数据类型的处理功能，并且资源和/或设备使用在数据位中编码的类型位和处理数据来确定数据类型。

公开(公告)号：US07859673B2

公开(公告)日：2010-12-28

申请号：US11822152

申请日：2007-07-02

Applicant: Gunter Moehler ,  Dietmar Schmidt ,  Mirko Liedtke

Inventor： Gunter Moehler ,  Dietmar Schmidt ,  Mirko Liedtke

IPC: G01N21/55 ,  H03K19/14

CPC classification number: G01J1/44 ,  G01J1/42 ,  G02B21/0076 ,  G02B21/008 ,  G02B21/16

Abstract: A method for detecting and analyzing light signals, in which a light signal impinges an optoelectric converter, where it is converted into an electric signal and the electric signal subsequent to the conversion is distributed into several analysis channels (13.1-13.4), within each analysis channel (13.1), (i) a signal analysis is performed, which is different from the signal analysis for the other analysis channels (13.2-13.4) and (ii) an output signal is created. In such a method, one or more output signals are selected for further processing and output using a specified, changeable selection criterion.

Abstract translation: 一种用于检测和分析其中光信号照射光电转换器的光信号的方法，其中它被转换为电信号，并且在转换之后的电信号被分配到多个分析通道（13.1-13.4）中，在每个分析 通道（13.1），（i）进行与其他分析通道（13.2-13.4）的信号分析不同的信号分析，（ii）产生输出信号。 在这种方法中，选择一个或多个输出信号用于使用指定的可变选择标准进一步处理和输出。

公开(公告)号：US07145652B2

公开(公告)日：2006-12-05

申请号：US10419016

申请日：2003-04-17

Applicant: Gunter Moehler ,  Ralf Wolleschensky ,  Mirko Liedtke

Inventor： Gunter Moehler ,  Ralf Wolleschensky ,  Mirko Liedtke

IPC: G01N15/02 ,  G02B21/00 ,  G01J3/28

CPC classification number: G02B21/06 ,  G02B26/007

Abstract: A microscope with optical components which are provided in the illumination beam path and/or observation beam path and/or detection beam path for exerting different spectral influences on at least one of the beam paths mentioned above. An arrangement comprising a light source emitting a plurality of wavelengths and at least one spectral sensor detecting the light of this light source after interacting with a component are provided, preferably outside these beam paths. The interaction is carried out by transmission or reflection of the light by the component. The detected values of the spectral sensor are compared to pre-stored values and correlation with pre-stored values is advantageously carried out in a storage. The correlation is carried out together with a position signal of a component changer. The detected values are stored separately and together with a position signal of a component changer when there is no correlation with pre-stored values.

公开(公告)号：US07869123B2

公开(公告)日：2011-01-11

申请号：US11806458

申请日：2007-05-31

Applicant: Gunter Moehler ,  Mirko Liedtke

Inventor： Gunter Moehler ,  Mirko Liedtke

IPC: G02B21/00

CPC classification number: H04L12/407 ,  G02B21/008 ,  G02B21/365 ,  H04L2012/40215

Abstract: Specimen laser-scanning microscope with raster scanning illumination and detector modules, which illuminates and detects a specimen by raster scanning. A real-time control device (device) performs synchronous reading-out with the raster scanning pixel cycle. A data port serially communicates with the device using a bidirectional high-speed data stream and with the resources via a serial, bidirectional high-speed data stream with a data conversion to/from parallel to serial. The high-speed data stream is made up of data packets with data bits and type bits and no additional header or protocol bits. The data bits contain data from/on the resources and the type bits code the type of data. Type information is stored in the resources as well as the device. The type information defines processing functions for data types coded by the type bits, and the resources and/or the device determine the data type using type bits and process data coded in the data bits.

Abstract translation: 具有光栅扫描照明和检测器模块的样品激光扫描显微镜，其通过光栅扫描照亮和检测样品。 实时控制装置（装置）利用光栅扫描像素周期执行同步读出。 数据端口使用双向高速数据流和通过串行双向高速数据流与资源串行地与设备进行通信，数据转换到并行到串行数据转换。 高速数据流由具有数据位和类型位的数据分组组成，没有附加的报头或协议位。 数据位包含来自资源的数据，类型位代码数据类型。 类型信息存储在资源以及设备中。 类型信息定义由类型位编码的数据类型的处理功能，并且资源和/或设备使用在数据位中编码的类型位和处理数据来确定数据类型。

公开(公告)号：US20090129032A1

公开(公告)日：2009-05-21

申请号：US12064577

申请日：2006-07-07

Applicant: Mirko Liedtke ,  Gunter Moehler

Inventor： Mirko Liedtke ,  Gunter Moehler

IPC: H05K5/00

CPC classification number: H02J1/14 ,  H02J13/0003 ,  Y02B90/228 ,  Y04S20/18

Abstract: The invention relates to a modular system comprising a primary module, several individual modules that can be connected to said primary module and a power supply unit that is connected to the primary module and supplies the connected individual modules with a voltage. According to the invention, the system is equipped with a descriptor element for each individual module. The descriptor element is read by the primary module and encodes or displays the power requirements of the assigned individual module. The primary module reads the descriptor elements of the connected individual modules and uses said elements to determine the total power requirements of the modular system, or of all connected individual modules.

Abstract translation: 本发明涉及一种模块化系统，其包括主模块，可以连接到所述主模块的几个单独模块和连接到主模块并且向连接的各个模块提供电压的电源单元。 根据本发明，系统配备有用于每个单独模块的描述符元素。 描述符元素由主模块读取并编码或显示分配的单独模块的功率需求。 主模块读取连接的各个模块的描述符元素，并使用所述元素来确定模块化系统或所有连接的各个模块的总功率需求。

公开(公告)号：US20080008479A1

公开(公告)日：2008-01-10

申请号：US11822152

申请日：2007-07-02

Applicant: Gunter Moehler ,  Dietmar Schmidt ,  Mirko Liedtke

Inventor： Gunter Moehler ,  Dietmar Schmidt ,  Mirko Liedtke

IPC: H04B10/06

CPC classification number: G01J1/44 ,  G01J1/42 ,  G02B21/0076 ,  G02B21/008 ,  G02B21/16

Abstract: A method for detecting and evaluating light signals, in which a light signal impinges an optoelectric converter, where it is converted into an electric signal and the electric signal subsequent to the conversion is distributed into several evaluation channels (13.1-13.4), within each evaluation channel (13.1), (i) a signal evaluation is performed, which is different form the signal evaluation for the other evaluation channels (13.2-13.4) and (ii) a result signal is created. In such a method, one or more result signals are selected for further processing and displayed using a predetermined variably adjustable selection criterion.

Abstract translation: 一种用于检测和评估光信号的光信号的方法，其中光信号照射光电转换器，其中它被转换为电信号，并且在转换之后的电信号被分配到多个评估通道（13.1-13.4）中，在每个评估 通道（13.1），（i）执行信号评估，其与其他评估通道（13.2-13.4）的信号评估不同，并且（ii）产生结果信号。 在这种方法中，选择一个或多个结果信号用于进一步处理，并使用预定的可变调节的选择标准进行显示。

公开(公告)号：US20060000984A1

公开(公告)日：2006-01-05

申请号：US11182465

申请日：2005-07-15

Applicant: Ralf Wolleschensky ,  Gunter Moehler ,  Volker Gerstner

Inventor： Ralf Wolleschensky ,  Gunter Moehler ,  Volker Gerstner

IPC: G01J1/58 ,  F21V9/16

CPC classification number: G02B21/0004 ,  G02B21/16

Abstract: A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.

公开(公告)号：US06747737B2

公开(公告)日：2004-06-08

申请号：US09895518

申请日：2001-06-28

Applicant: Ralf Wolleschensky ,  Gunter Moehler

Inventor： Ralf Wolleschensky ,  Gunter Moehler

IPC: G01J328

CPC classification number: G02B21/002 ,  G02B21/06

Abstract: In light detection systems for illuminating specimens having a plurality of detection channels, particularly channels employing laser scanning microscopes, an improved method comprises assigning an upper and/or lower limiting value which is adjustable for at least one channel and changing the channel to be detected with respect to its mode of operation when the limiting value is reached.

Abstract translation: 在用于照射具有多个检测通道的样品的光检测系统中，特别是使用激光扫描显微镜的通道，改进的方法包括分配对于至少一个通道可调节的上限值和/或下限值，并且用 当达到极限值时，其操作模式。

公开(公告)号：US6037583A

公开(公告)日：2000-03-14

申请号：US010079

申请日：1998-01-21

Applicant: Gunter Moehler ,  Guenter Schoeppe ,  Sebastian Tille

Inventor： Gunter Moehler ,  Guenter Schoeppe ,  Sebastian Tille

IPC: G02B21/00 ,  H01J3/14

CPC classification number: G02B21/002

Abstract: A control system for a scanner is disclosed, especially for a laser scanning microscope, with an oscillating motor for driving an oscillating mirror serving for the linearly oscillating deflection of a beam bundle, with a control unit for supplying the oscillating motor with an exciting current which is variable with respect to the control frequency, frequency curve, and amplitude, with a function generator which is connected with the control unit, and with a measurement value transducer for obtaining a sequence of information about the deflection positions of the oscillating mirror.The measurement value transducer is connected with the function generator by way of a logic unit for determining correction values for the exciting current. Accordingly, it is advantageously possible, by evaluating the information supplied by the measurement value transducer about the actual deflection position of the oscillating mirror, to determine correction values with the assistance of the logic unit. These correction values can be used, in turn, to influence the control frequencies emitted by the function generator in such a way that deviations are minimized or completely prevented.

Abstract translation: 公开了一种用于扫描仪的控制系统，特别是用于激光扫描显微镜，具有用于驱动用于束束的线性振荡偏转的振荡镜的振荡电机，具有用于向振荡电机供应励磁电流的控制单元 相对于控制频率，频率曲线和幅度可变，与控制单元连接的函数发生器，以及用于获得关于振荡反射镜的偏转位置的信息序列的测量值传感器。 测量值传感器通过逻辑单元与功能发生器连接，用于确定激励电流的校正值。 因此，通过评估由测量值传感器提供的关于振荡镜的实际偏转位置的信息，有利于在逻辑单元的协助下确定校正值是有利的。 可以使用这些校正值，从而以使偏差最小化或完全防止的方式影响函数发生器发出的控制频率。

公开(公告)号：US20090228618A1

公开(公告)日：2009-09-10

申请号：US12379193

申请日：2009-02-13

Applicant: Andreas Kuehm ,  Nico Presser ,  Gunter Moehler

Inventor： Andreas Kuehm ,  Nico Presser ,  Gunter Moehler

IPC: G06F3/00

CPC classification number: G06F13/4059

Abstract: A peripheral interface and process for data transfer, especially for laser scanning microscopes. The peripheral interface permits a gap-free transfer of data with high transmission speed at low cost and using a non-real-time-enabled operating system of the control computer. In a peripheral interface having a connection for a system bus of a control computer, a peripheral connection for a peripheral device and a control unit serving for one-way transmission of a predetermined amount of data from the control computer to the peripheral device and/or vice versa accesses via the system bus, a work memory region of the control computer serves as buffers preassigned to it, where the control unit prepares for the control computer a progress report of the transfer for retrieval and the control unit of the control computer is informed of the progress of the processing of the buffer independently of the transfer, in which case it allows for the progress of the processing when accessing the buffer. The peripheral device can be part of a laser scanning microscope.

Abstract translation: 用于数据传输的外围接口和过程，尤其适用于激光扫描显微镜。 外围接口允许以低成本传输高传输速率的数据，并使用控制计算机的非实时启用操作系统。 在具有用于控制计算机的系统总线的连接的外围接口中，用于外围设备的外围连接和用于从控制计算机向外围设备单向传输预定数量的数据的控制单元和/或 反过来通过系统总线访问，控制计算机的工作存储器区域用作预先分配给它的缓冲器，其中控制单元为控制计算机准备用于检索的传送的进度报告，并且控制计算机的控制单元被通知 独立于传输处理缓冲区的进度，在这种情况下，它允许在访问缓冲区时进行处理。 外围设备可以是激光扫描显微镜的一部分。