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    Antiphlogistic pharmaceutical compositions containing a phenylethanolamine and methods of use
    1.
    发明授权
    Antiphlogistic pharmaceutical compositions containing a phenylethanolamine and methods of use 失效
    含有苯乙醇胺的消炎药物组合物及其使用方法

    公开(公告)号：US4244967A

    公开(公告)日：1981-01-13

    申请号：US72553

    申请日：1979-09-04

    申请人： Gunther Engelhardt ,  Johannes Keck ,  Gerd Kruger ,  Klaus Noll ,  Helmut Pieper ,  Rainer Zimmermann

    发明人： Gunther Engelhardt ,  Johannes Keck ,  Gerd Kruger ,  Klaus Noll ,  Helmut Pieper ,  Rainer Zimmermann

    IPC分类号： A61K31/135 ,  A61K31/17 ,  A61K31/275 ,  A61K31/325 ,  A61P29/00 ,  A61P43/00 ,  A61K31/27

    CPC分类号： A61K31/135 ,  A61K31/17 ,  A61K31/275 ,  A61K31/325

    摘要： The method of using compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine, bromine, iodine or cyano,R.sub.2 is fluorine, cyano, trifluoromethyl, nitro or alkyl of 1 to 4 carbon atoms,R.sub.3 is cycloalkyl or alkyl, each of 3 to 5 carbon atoms, andR.sub.4 is hydrogen or --CO--R.sub.5, whereR.sub.5 is alkoxy of 1 to 5 carbon atoms, alkenyloxy of 2 to 5 carbon atoms, aryloxy of 6 to 10 carbon atoms, aralkoxy of 7 to 11 carbon atoms, or amino which may be mono- or di-substituted by alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms, aryl of 6 to 10 carbon atoms and/or aralkyl of 7 to 11 carbon atoms,and non-toxic, pharmacologically acceptable acid addition salts thereof as antirheumatics and antiphlogistics.

    摘要翻译： 使用下式化合物的方法其中R1是氢，氟，氯，溴，碘或氰基，R2是氟，氰基，三氟甲基，硝基或1-4个碳原子的烷基，R3是环烷基或烷基， 3〜5个碳原子，R4为氢或-CO-R5，R5为1〜5个碳原子的烷氧基，2〜5个碳原子的烯氧基，6〜10个碳原子的芳氧基，7〜11个芳氧基 碳原子或可以被1至5个碳原子的烷基，2至5个碳原子的烯基，6至10个碳原子的芳基和/或7至11个碳原子的芳烷基单取代或二取代的氨基，以及 无毒，药理学上可接受的酸加成盐作为抗风湿剂和消炎药。

    Esters and amides containing the 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl moiety
    2.
    发明授权
    Esters and amides containing the 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl moiety 失效
    含有1-（4-氯苯甲酰基）-5-甲氧基-2-甲基-1H-吲哚-3-乙酰基部分的酯和酰胺

    公开(公告)号：US4362738A

    公开(公告)日：1982-12-07

    申请号：US158587

    申请日：1980-06-11

    申请人： Johannes Keck ,  Gerd Kruger ,  Helmut Pieper ,  Klaus Noll ,  Gunther Engelhardt ,  Norbert Promberger ,  Rainer Zimmermann

    发明人： Johannes Keck ,  Gerd Kruger ,  Helmut Pieper ,  Klaus Noll ,  Gunther Engelhardt ,  Norbert Promberger ,  Rainer Zimmermann

    IPC分类号： C07D209/08 ,  A61K31/495 ,  A61P29/00 ,  C07C67/00 ,  C07C227/00 ,  C07C227/16 ,  C07C227/18 ,  C07C229/54 ,  C07C237/32 ,  C07C237/38 ,  C07C313/00 ,  C07C323/12 ,  C07C323/65 ,  C07D209/28 ,  C07D213/74 ,  C07D295/088 ,  C07D295/155 ,  C07D401/12 ,  C07H13/08 ,  C07D279/18 ,  A61K27/00

    CPC分类号： C07D213/74 ,  C07D209/28 ,  C07D295/088 ,  C07D295/155

    摘要： Compounds of the formula ##STR1## wherein each X, which may be identical or different from the other X, is oxygen or imino;R.sub.1 is hydrogen, fluorine, chlorine or bromine;R.sub.2 and R.sub.3, which may be identical or different from each other, are each hydrogen; unsubstituted or mono-substituted alkyl of 1 to 6 carbon atoms, where the substituent is phenyl or dialkylamino with 1 to 3 carbon atoms in each alkyl moiety; pyridyl; or cycloalkyl of 5 to 7 carbon atoms;R.sub.2 and R.sub.3, together with each other and the nitrogen atoms to which they are attached, are pyrrolidino, piperidino, hexamethyleneimino, morpholino, N-aryl-piperazino or N-(alkyl of 1 to 3 carbon atoms)-piperazino;A is cycloalkylene of 5 to 7 carbon atoms; unsubstituted or substituted alkylene of 2 to 10 carbon atoms, where the substituents are one to two alkyls of 1 to 3 carbon atoms each, one to two carbalkoxys of 2 to 4 carbon atoms each, one to two phenyls, one to four hydroxyls, one halomethyl, one hydroxymethyl, one alkanoyloxy of 1 to 18 carbon atoms, one alkanoyloxymethyl of 1 to 18 carbon atoms in the alkanoyl moiety or one ##STR2## where R.sub.1, R.sub.2 and R.sub.3 have the meanings previously defined; or alkylene of 2 to 10 carbon atoms interrupted by oxygen, sulfur, sulfoxide, sulfonyl, phenyl, cyclohexyl, pyridyl, piperazino or unsubstituted or substituted imino, where the substituent on the imino group is alkyl of 1 to 6 carbon atoms, phenyl or phenylalkyl of 1 to 3 carbon atoms in the alkyl moiety;B is the acyl residue of an antiphlogistic carboxylic acid;and their non-toxic, pharmacologically acceptable acid addition salts. The compounds as well as their salts are useful as anti-inflammatories.

    摘要翻译： 其中每个X可以相同或不同于另一个X的式“IMAGE”的化合物是氧或亚氨基; R1是氢，氟，氯或溴; R2和R3可以相同或不同，分别为氢; 未取代或单取代的1至6个碳原子的烷基，其中取代基为苯基或每个烷基部分具有1至3个碳原子的二烷基氨基; 吡啶基 或5至7个碳原子的环烷基; 吡咯烷基，哌啶子基，六亚甲基亚氨基，吗啉代，N-芳基 - 哌嗪子基或N-（1至3个碳原子的烷基） - 哌嗪基; R 2和R 3彼此连接并连接的氮原子。 A是5至7个碳原子的亚环烷基; 2至10个碳原子的未取代或取代的亚烷基，其中取代基为1至2个碳原子数为1至2个的烷基，每个为2至4个碳原子的1至2个碳烷氧基，1至2个苯基，1至4个羟基，1至2个 卤代甲基，一个羟甲基，一个1至18个碳原子的烷酰氧基，一个在烷酰基部分中具有1至18个碳原子的烷酰氧基甲基或一个，其中R1，R2和R3具有以前定义的含义; 或由氧，硫，亚砜，磺酰基，苯基，环己基，吡啶基，哌嗪子基或未取代或取代的亚氨基所取代的2至10个碳原子的亚烷基，其中亚氨基上的取代基是1至6个碳原子的烷基，苯基或苯基烷基 在烷基部分中具有1至3个碳原子; B是消炎性羧酸的酰基残基; 及其无毒，药理学上可接受的酸加成盐。 化合物及其盐可用作抗炎剂。

    METHOD FOR OPERATING A NAVIGATION SYSTEM AND NAVIGATION SYSTEM FOR A MOTOR VEHICLE
    6.
    发明申请
    METHOD FOR OPERATING A NAVIGATION SYSTEM AND NAVIGATION SYSTEM FOR A MOTOR VEHICLE 有权
    用于操作电动汽车的导航系统和导航系统的方法

    公开(公告)号：US20100274422A1

    公开(公告)日：2010-10-28

    申请号：US12602302

    申请日：2008-04-24

    申请人： Rolf Schrey ,  Bruno Bozionek ,  Rainer Zimmermann

    发明人： Rolf Schrey ,  Bruno Bozionek ,  Rainer Zimmermann

    IPC分类号： G01C21/36 ,  B60W20/00 ,  B60W10/06 ,  B60W10/08

    CPC分类号： G01C21/3461

    摘要： The invention relates to a method for operating a navigation system for a motor vehicle in a road network, and to a navigation system. To this end, first a zone of the road network is provided with an emissions class-dependent drive-through restriction, wherein the motor vehicle is associated with at least one emissions class. First, information about the geographical location of the zone and about the emissions class at least required there is stored in the navigation system. Then, information about the at least one emissions class of the motor vehicle is entered into the navigation system. Thereafter, the information entered is considered in the destination guidance process, wherein destination guidance into or through the zone is avoided if the at least one emissions class of the motor vehicle is affected by emissions class-dependent drive-through restrictions in the zone.

    摘要翻译： 本发明涉及一种用于操作道路网络中的机动车辆的导航系统和导航系统的方法。 为此，首先，道路网络的区域被提供有排放等级相关的驱动限制，其中机动车辆与至少一个排放类别相关联。 首先，在导航系统中存储有关该区域的地理位置和关于排放等级至少需要的信息。 然后，将关于汽车的至少一个排放等级的信息输入导航系统。 此后，在目的地引导过程中考虑输入的信息，其中如果机动车辆的至少一个排放类别受到该区域中的排放等级相关的驱动限制的影响，则避免进入或通过该区域的目的地引导。

    Method for realizing a presence service and presence system
    7.
    发明申请
    Method for realizing a presence service and presence system 有权
    实现在线服务和存在系统的方法

    公开(公告)号：US20090191851A1

    公开(公告)日：2009-07-30

    申请号：US11547519

    申请日：2005-08-29

    申请人： Manfred Hutt ,  Florian Nierhaus ,  Rainer Zimmermann

    发明人： Manfred Hutt ,  Florian Nierhaus ,  Rainer Zimmermann

    IPC分类号： H04M3/42

    CPC分类号： H04L67/24

    摘要： In one aspect, a method for realizing a presence service with a buddy list that can be displayed on a display device of a terminal is provided. In an activated state, the buddy list itself is displayed, and in a deactivated state, the buddy list itself is not visible. The buddy list is updated by a control device during a change in state of at lest one subscriber to be monitored and/or of at least one device assigned to the subscriber. According to the invention, the updating of the buddy list ensues in the deactivated state by means of the control device while using a method other than one used in the activated state.

    摘要翻译： 一方面，提供了一种用于实现可以在终端的显示装置上显示的好友列表的存在服务的方法。 在激活状态下，显示好友列表本身，处于停用状态时，好友列表本身不可见。 在至少一个要监视的用户的状态改变和/或分配给订户的至少一个设备的状态下，控制设备更新好友列表。 根据本发明，利用控制装置在使用不同于在激活状态中使用的方法之外的方法时，更新好友列表处于停用状态。

    System for computer-aided monitoring of the use of licenses
    8.
    发明授权
    System for computer-aided monitoring of the use of licenses 有权
    计算机辅助监控使用许可证的系统

    公开(公告)号：US07222367B2

    公开(公告)日：2007-05-22

    申请号：US10198743

    申请日：2002-07-19

    申请人： Werner Behr ,  Ralf Brese ,  Rainer Zimmermann ,  Bruno Bozionek ,  Achim Minderlein

    发明人： Werner Behr ,  Ralf Brese ,  Rainer Zimmermann ,  Bruno Bozionek ,  Achim Minderlein

    IPC分类号： G06F21/00 ,  H04N7/167

    CPC分类号： G06F21/105

    摘要： The use of licenses is monitored in a computer or communication system which has a plurality of terminals and in which at least one license is associated with at least one user. The use of the license or licenses by each user is recorded during a defined period after the license starts to run. Based on the recording result, a message is generated and sent to the user's terminal at least if the scope of use falls short of a predeterminable value.

    摘要翻译： 在具有多个终端并且至少一个许可与至少一个用户相关联的计算机或通信系统中监视许可证的使用。 每个用户使用许可证或许可证将在许可证开始运行后的定义期间进行记录。 基于记录结果，生成消息并至少在使用范围低于可预定值的情况下发送给用户终端。

    Method and arrangement for managing documents in electronic document folders
    9.
    发明授权
    Method and arrangement for managing documents in electronic document folders 有权
    在电子文件夹中管理文件的方法和装置

    公开(公告)号：US09268771B2

    公开(公告)日：2016-02-23

    申请号：US11664145

    申请日：2005-09-05

    申请人： Bruno Bozionek ,  Thomas Hanna ,  Klaus-Josef Kunte ,  Rainer Zimmermann

    发明人： Bruno Bozionek ,  Thomas Hanna ,  Klaus-Josef Kunte ,  Rainer Zimmermann

    IPC分类号： G06F17/30 ,  G06Q10/10

    CPC分类号： G06F17/30 ,  G06Q10/107

    摘要： In one aspect, a method for managing documents or partial documents in an electronic document folder is provided. A validity indication, which is individual to the document or partial document and specifies a validity expiry time is assigned to a respective document, e.g. an e-mail, or a partial document, e.g. an e-mail attachment and is stored, the indication being assigned to an executable validity program. Once the validity expiry time has been reached, the executable validity program, assigned to the validity indication, is executed for the document or partial document with an assigned validity indication. The executable validity program comprises a deletion routine for deleting the document or partial document with the assigned validity indication in the electronic document folder.

    摘要翻译： 一方面，提供一种用于在电子文件夹中管理文档或部分文档的方法。 对于文档或部分文档是个人的，并且指定有效期限时间的有效性指示被分配给相应的文档，例如， 电子邮件或部分文档，例如。 电子邮件附件并被存储，该指示被分配给可执行的有效性程序。 一旦达到有效期到期，分配给有效性指示的可执行有效性程序对于具有分配的有效性指示的文档或部分文档执行。 可执行有效性程序包括用于在电子文档文件夹中具有分配的有效性指示来删除文档或部分文档的删除例程。