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公开(公告)号:US20230201266A1
公开(公告)日:2023-06-29
申请号:US17470487
申请日:2021-09-09
Inventor: Feng-Huei Lin , Che-Yung Kuan , Yu-Ying Lin , Ching-Yun Chen , Zhi-Yu Chen , I-Hsuan Yang , Ming-Hsi Chuang , Po-Cheng Lin , Chia-Hsin Lee , Kai-Ling Zhang , Pei-Syuan Chao , Wan-Sin Syu , Chun-Hung Chen , Ting-Ju Wang
IPC: A61K35/28 , A61P19/02 , C12N5/0775 , C12N5/00
CPC classification number: A61K35/28 , A61P19/02 , C12N5/0062 , C12N5/0667 , C12N2513/00 , C12N2533/30
Abstract: The present disclosure provides a method for treating arthritis by using a stem cell preparation. The stem cell preparation of the present disclosure can effectively delay cartilage degeneration caused by arthritis, and it is confirmed by whole blood analysis and blood biochemical analysis that the stem cell preparation in the form of three-dimensional stem cell spheres provides a safe treatment for arthritis. The present disclosure also provides a method for preparing the stem cell preparation.
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公开(公告)号:US20190136195A1
公开(公告)日:2019-05-09
申请号:US16237399
申请日:2018-12-31
Inventor: Shao-Chih Chiu , Wan-Sin Syu , Ming-Hsi Chuang , Po-Cheng Lin
IPC: C12N5/0775 , A61K35/28
Abstract: A composition for treatment of tendonitis is provided. The composition comprises a pretreated adipose derived stem cell (ADSC), wherein the ADSC is pretreated with butylidenephthalide, and the concentration of butylidenephthalide is greater or equal to. The composition of the invention has abilities to repair damaged tendon fiber, enhance tissue regeneration, and decrease inflammation. The invention also provides a method for manufacturing a composition for treatment of tendonitis, comprising culturing an ADSC in a medium containing butylidenephthalide.
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公开(公告)号:US20180127722A1
公开(公告)日:2018-05-10
申请号:US15416502
申请日:2017-01-26
Inventor: Shao-Chih Chiu , Wan-Sin Syu , Ming-Hsi Chuang , Po-Cheng Lin
IPC: C12N5/0775 , A61K35/28
CPC classification number: C12N5/0667 , A61K35/28 , C12N2500/30 , C12N2500/76
Abstract: A composition for treatment of tendonitis is provided. The composition comprises a pretreated adipose derived stem cell (ADSC), wherein the ADSC is pretreated with butylidenephthalide, and the concentration of butylidenephthalide is greater or equal to. The composition of the invention has abilities to repair damaged tendon fiber, enhance tissue regeneration, and decrease inflammation. The invention also provides a method for manufacturing a composition for treatment of tendonitis, comprising culturing an ADSC in a medium containing butylidenephthalide.
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