公开(公告)号：US20250092356A1

公开(公告)日：2025-03-20

申请号：US18964649

申请日：2024-12-01

Applicant: Gwo Xi Stem Cell Applied Technology Co., Ltd.

Inventor： Ruei-Yue Liang ,  Kai-Ling Zhang ,  Ming-Hsi Chuang ,  Po-Cheng Lin ,  Chun-Hung Chen ,  Pei-Syuan Chao

IPC: C12N5/00 ,  C12N5/071

Abstract: The present invention relates to a cell differentiation medium composition, a high secretion insulin-producing cells and a preparation method thereof. The high secretion insulin-producing cells obtained by using the cell differentiation medium composition to induce stem cell differentiated under specific conditions can secrete a large amount of insulin in a short time, and when the high-secreting insulin-producing cells are transplanted into the human body, they are not easy to be swallowed by macrophages, which can improve the survival rate of the insulin-producing cells and prolong the time of insulin secretion thereby.

公开(公告)号：US20210371812A1

公开(公告)日：2021-12-02

申请号：US17235910

申请日：2021-04-20

Applicant: Gwo Xi Stem Cell Applied Technology Co., Ltd.

Inventor： Ruei-Yue Liang ,  Kai-Ling Zhang ,  Ming-Hsi Chuang ,  Po-Cheng Lin ,  Chun-Hung Chen ,  Pei-Syuan Chao

IPC: C12N5/00 ,  C12N5/071

Abstract: The present invention relates to a cell differentiation medium composition, a high secretion insulin-producing cells and a preparation method thereof. The high secretion insulin-producing cells obtained by using the cell differentiation medium composition to induce stem cell differentiated under specific conditions can secrete a large amount of insulin in a short time, and when the high-secreting insulin-producing cells are transplanted into the human body, they are not easy to be swallowed by macrophages, which can improve the survival rate of the insulin-producing cells and prolong the time of insulin secretion thereby.

公开(公告)号：US12195754B2

公开(公告)日：2025-01-14

申请号：US17235910

申请日：2021-04-20

Applicant: Gwo Xi Stem Cell Applied Technology Co., Ltd.

Inventor： Ruei-Yue Liang ,  Kai-Ling Zhang ,  Ming-Hsi Chuang ,  Po-Cheng Lin ,  Chun-Hung Chen ,  Pei-Syuan Chao

IPC: C12N5/00 ,  C12N5/071

Abstract: The present invention relates to a cell differentiation medium composition, a high secretion insulin-producing cells and a preparation method thereof. The high secretion insulin-producing cells obtained by using the cell differentiation medium composition to induce stem cell differentiated under specific conditions can secrete a large amount of insulin in a short time, and when the high-secreting insulin-producing cells are transplanted into the human body, they are not easy to be swallowed by macrophages, which can improve the survival rate of the insulin-producing cells and prolong the time of insulin secretion thereby.

公开(公告)号：US20230201266A1

公开(公告)日：2023-06-29

申请号：US17470487

申请日：2021-09-09

Applicant: GWO XI STEM CELL APPLIED TECHNOLOGY CO., LTD.

Inventor： Feng-Huei Lin ,  Che-Yung Kuan ,  Yu-Ying Lin ,  Ching-Yun Chen ,  Zhi-Yu Chen ,  I-Hsuan Yang ,  Ming-Hsi Chuang ,  Po-Cheng Lin ,  Chia-Hsin Lee ,  Kai-Ling Zhang ,  Pei-Syuan Chao ,  Wan-Sin Syu ,  Chun-Hung Chen ,  Ting-Ju Wang

IPC: A61K35/28 ,  A61P19/02 ,  C12N5/0775 ,  C12N5/00

CPC classification number: A61K35/28 ,  A61P19/02 ,  C12N5/0062 ,  C12N5/0667 ,  C12N2513/00 ,  C12N2533/30

Abstract: The present disclosure provides a method for treating arthritis by using a stem cell preparation. The stem cell preparation of the present disclosure can effectively delay cartilage degeneration caused by arthritis, and it is confirmed by whole blood analysis and blood biochemical analysis that the stem cell preparation in the form of three-dimensional stem cell spheres provides a safe treatment for arthritis. The present disclosure also provides a method for preparing the stem cell preparation.