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公开(公告)号:US10183477B2
公开(公告)日:2019-01-22
申请号:US14648446
申请日:2013-12-02
申请人: H. David Dean , Al Siblani , Eric J. Mott , John P. Fisher , Martha O. Wang , Antonios G. Mikos
发明人: H. David Dean , Al Siblani , Eric J. Mott , John P. Fisher , Martha O. Wang , Antonios G. Mikos
IPC分类号: B33Y50/00 , A61L27/50 , B33Y30/00 , B33Y80/00 , A61L27/56 , G02B26/08 , A61L27/60 , B29C64/135
摘要: A light-polymerizable composition for additive manufacturing of resorbable scaffolds and implants comprising a biocompatible resin. The biocompatible resin includes a combination of photo-initiators or a dye-initiator package tailored to manufacture implants with the desired physical and chemical properties. A dye or other constituent controls between layer (z) resolution of the manufactured part built in an additive manufacturing device. A light absorber or other constituent controls within layer (x-y) resolution of the manufactured part.
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公开(公告)号:US11865785B2
公开(公告)日:2024-01-09
申请号:US15634792
申请日:2017-06-27
申请人: H. David Dean , Al Siblani , Eric J. Mott , John P. Fisher , Martha O. Wang , Antonios G. Mikos
发明人: H. David Dean , Al Siblani , Eric J. Mott , John P. Fisher , Martha O. Wang , Antonios G. Mikos
IPC分类号: A61L27/56 , B29C64/386 , A61L27/50 , B33Y30/00 , B33Y80/00 , A61L27/60 , B33Y50/00 , B33Y70/00 , G03F7/105 , G03F7/029 , G03F7/20 , G03F7/004 , B29C64/135 , G02B26/08
CPC分类号: B29C64/386 , A61L27/50 , A61L27/56 , A61L27/60 , B33Y30/00 , B33Y50/00 , B33Y70/00 , B33Y80/00 , G03F7/0047 , G03F7/029 , G03F7/105 , G03F7/2008 , B29C64/135 , G02B26/0833
摘要: A process for additive manufacturing of a resorbable implant to be implanted into a patient includes providing a biocompatible resin including a liquid light-polymerizable material that is resorbable after polymerization and an initiator. The process further includes actuating an additive manufacturing apparatus to expose an amount of the biocompatible resin to light to at least partially cure the exposed amount of biocompatible resin to form a layer of the resorbable implant and actuating the additive manufacturing apparatus to expose at least some additional amount of biocompatible resin to light to at least partially cure the exposed additional amount of biocompatible resin to form an additional layer of the resorbable implant and to at least partially overcure previously cured layers to cause at least some interlayer binding between the previously cured layers and the additional layer.
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公开(公告)号:US09688023B2
公开(公告)日:2017-06-27
申请号:US13817612
申请日:2011-08-22
申请人: H. David Dean , Jonathan E. Wallace , Antonios G. Mikos , Martha Wang , Ali Siblani , Kyobum Kim , John P. Fisher
发明人: H. David Dean , Jonathan E. Wallace , Antonios G. Mikos , Martha Wang , Ali Siblani , Kyobum Kim , John P. Fisher
CPC分类号: B29C67/0066 , A61L27/50 , A61L27/56 , A61L27/60 , B29C64/135 , B33Y30/00 , B33Y50/00 , B33Y80/00 , G02B26/0833
摘要: A process for additive manufacturing of a resorbable implant to be implanted into a patient includes providing a biocompatible resin including a liquid light-polymerizable material that is resorbable after polymerization and an initiator. The process further includes actuating an additive manufacturing apparatus to expose an amount of the biocompatible resin to light to at least partially cure the exposed amount of biocompatible resin to form a layer of the resorbable implant and actuating the additive manufacturing apparatus to expose at least some additional amount of biocompatible resin to light to at least partially cure the exposed additional amount of biocompatible resin to form an additional layer of the resorbable implant and to at least partially overcure previously cured layers to cause at least some interlayer binding between the previously cured layers and the additional layer.
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公开(公告)号:US20130304233A1
公开(公告)日:2013-11-14
申请号:US13817612
申请日:2011-08-22
申请人: H. David Dean , Jonathan E. Wallace , Antonios G. Mikos , Martha Wang , Ali Siblani , Kyobum Kim , John P. Fisher
发明人: H. David Dean , Jonathan E. Wallace , Antonios G. Mikos , Martha Wang , Ali Siblani , Kyobum Kim , John P. Fisher
IPC分类号: A61L27/60
CPC分类号: B29C67/0066 , A61L27/50 , A61L27/56 , A61L27/60 , B29C64/135 , B33Y30/00 , B33Y50/00 , B33Y80/00 , G02B26/0833
摘要: A process for additive manufacturing of a resorbable implant to be implanted into a patient includes providing a biocompatible resin including a liquid light-polymerizable material that is resorbable after polymerization and an initiator. The process further includes actuating an additive manufacturing apparatus to expose an amount of the biocompatible resin to light to at least partially cure the exposed amount of biocompatible resin to form a layer of the resorbable implant and actuating the additive manufacturing apparatus to expose at least some additional amount of biocompatible resin to light to at least partially cure the exposed additional amount of biocompatible resin to form an additional layer of the resorbable implant and to at least partially overcure previously cured layers to cause at least some interlayer binding between the previously cured layers and the additional layer.
摘要翻译: 可植入患者的可再吸收植入物的添加制造方法包括提供生物相容性树脂,其包括在聚合后可再吸收的液体光可聚合材料和引发剂。 该方法还包括致动添加剂制造设备以将一定量的生物相容性树脂暴露于光以至少部分地固化暴露量的生物相容性树脂以形成可再吸收的植入物的层并致动添加剂制造设备以暴露至少一些附加的 生物相容性树脂的量至少部分地固化暴露的额外量的生物相容性树脂以形成另外的可再吸收植入物层,并且至少部分地过度固化先前固化的层,以在先前固化的层之间至少部分层间结合 附加层。
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公开(公告)号:US20130018497A1
公开(公告)日:2013-01-17
申请号:US13616007
申请日:2012-09-14
IPC分类号: G05B19/18
CPC分类号: G06F19/3437 , A61B6/505 , A61F2/28 , A61F2/30942 , A61F2002/2835 , B33Y50/00 , B33Y80/00 , G06F19/00 , G06F19/321 , G06F19/3481 , G06K9/34 , G06K9/6251 , G06K2209/05 , G06T7/0014 , G06T17/00 , G06T2207/30008 , G16H50/50
摘要: A computer implemented method for determining the 3-dimensional shape of an implant to be implanted into a subject includes obtaining a computer readable image including a defective portion and a non-defective portion of tissue in the subject, superimposing on the image a shape to span the defective portion, and determining the 3-dimensional shape of the implant based on the shape that spans the defective portion.
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公开(公告)号:US09275191B2
公开(公告)日:2016-03-01
申请号:US13616007
申请日:2012-09-14
IPC分类号: A61B5/00 , G06F19/00 , G06T7/00 , A61F2/30 , G06K9/34 , G06K9/62 , G06T17/00 , A61F2/28 , A61B6/00
CPC分类号: G06F19/3437 , A61B6/505 , A61F2/28 , A61F2/30942 , A61F2002/2835 , B33Y50/00 , B33Y80/00 , G06F19/00 , G06F19/321 , G06F19/3481 , G06K9/34 , G06K9/6251 , G06K2209/05 , G06T7/0014 , G06T17/00 , G06T2207/30008 , G16H50/50
摘要: A computer implemented method for determining the 3-dimensional shape of an implant to be implanted into a subject includes obtaining a computer readable image including a defective portion and a non-defective portion of tissue in the subject, superimposing on the image a shape to span the defective portion, and determining the 3-dimensional shape of the implant based on the shape that spans the defective portion.
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