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公开(公告)号:US20200262850A1
公开(公告)日:2020-08-20
申请号:US16751823
申请日:2020-01-24
Applicant: HELSINN HEALTHCARE SA
Inventor: Claudio Giuliano , Silvina Garcia Rubio , Antoine Daina , Angelo Guainazzi , Claudio Pietra
IPC: C07F7/08 , C07D417/12 , C07D413/12 , C07D409/12 , C07D405/14 , C07D241/12 , C07D213/00 , C07D211/96 , C07D211/94 , C07D211/60 , C07D401/06 , C07D471/04 , C07D403/12 , C07D405/12 , C07D239/26 , C07D409/14 , C07D417/14 , C07D401/12 , C07D211/58 , C07D401/14
Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
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公开(公告)号:US20190062352A1
公开(公告)日:2019-02-28
申请号:US15889589
申请日:2018-02-06
Applicant: HELSINN HEALTHCARE SA
Inventor: Claudio Giuliano , Silvina Garcia Rubio , Antoine Daina , Angelo Guainazzi , Claudio Pietra
IPC: C07F7/08 , C07D471/04 , C07D401/06 , C07D405/12 , C07D239/26 , C07D409/14 , C07D417/14 , C07D401/12 , C07D211/58 , C07D401/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D241/12 , C07D405/14 , C07D213/00 , C07D211/96 , C07D211/94 , C07D211/60 , C07D403/12
Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
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公开(公告)号:US09926337B2
公开(公告)日:2018-03-27
申请号:US15368362
申请日:2016-12-02
Applicant: HELSINN HEALTHCARE SA
Inventor: Claudio Giuliano , Silvina Garcia Rubio , Antoine Daina , Angelo Guainazzi , Claudio Pietra
IPC: A61K31/17 , C07C275/26 , C07F7/08 , C07D401/14 , C07D211/58 , C07D401/12 , C07D417/14 , C07D409/14 , C07D239/26 , C07D405/12 , C07D403/12 , C07D471/04 , C07D401/06 , C07D211/60 , C07D211/94 , C07D211/96 , C07D213/00 , C07D241/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12
CPC classification number: C07F7/0812 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/96 , C07D213/00 , C07D239/26 , C07D241/12 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
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公开(公告)号:US09546157B2
公开(公告)日:2017-01-17
申请号:US14640551
申请日:2015-03-06
Applicant: Helsinn Healthcare SA
Inventor: Claudio Giuliano , Silvina Garcia Rubio , Antoine Daina , Angelo Guainazzi , Claudio Pietra
IPC: A61K31/4468 , C07D211/58 , C07D295/00 , C07D401/14 , C07D401/12 , C07D417/14 , C07D409/14 , C07D239/26 , C07D405/12 , C07D403/12 , C07D471/04 , C07D401/06 , C07D211/60 , C07D211/94 , C07D211/96 , C07D213/00
CPC classification number: C07F7/0812 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/96 , C07D213/00 , C07D239/26 , C07D241/12 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
Abstract translation: 公开了用于预防和/或治疗由生长素释放肽受体病理生理介导的疾病的化合物,组合物和方法。 化合物具有通式I或其药学上可接受的盐。
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公开(公告)号:US20170275301A1
公开(公告)日:2017-09-28
申请号:US15464430
申请日:2017-03-21
Applicant: HELSINN HEALTHCARE SA
Inventor: Claudio Giuliano , Antoine Daina , Claudio Pietra
IPC: C07D513/04 , C07C311/47 , C07C317/42 , C07D209/08 , C07D403/12 , C07D215/06 , C07D215/10 , C07D401/12 , C07D215/58 , C07D215/08 , C07D405/06 , C07D213/34 , C07D311/76 , C07D295/088 , C07D307/87 , C07D231/56 , C07D239/48 , C07D233/64 , C07D235/14 , C07D213/76 , C07D237/20 , C07D209/44 , C07D417/12 , C07D409/12 , C07D317/34 , C07D417/10 , C07D487/04 , C07D223/16 , C07D405/04 , C07D495/04 , C07D471/04 , C07D405/12 , C07D241/04 , C07D217/04 , C07D217/10 , C07D471/08 , C07D413/12 , C07D241/12
CPC classification number: C07D513/04 , C07C311/47 , C07C317/14 , C07C317/26 , C07C317/42 , C07C317/44 , C07C2601/02 , C07D209/04 , C07D209/08 , C07D209/44 , C07D213/34 , C07D213/76 , C07D215/06 , C07D215/08 , C07D215/10 , C07D215/58 , C07D217/04 , C07D217/10 , C07D223/16 , C07D231/56 , C07D233/64 , C07D235/14 , C07D237/20 , C07D239/26 , C07D239/48 , C07D241/04 , C07D241/12 , C07D295/088 , C07D307/87 , C07D311/76 , C07D317/34 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/10 , C07D417/12 , C07D471/04 , C07D471/08 , C07D487/04 , C07D495/04
Abstract: Benzenesulfonyl-asymmetric ureas are provided for the treatment of conditions modulated by the ghrelin receptor.
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公开(公告)号:US20150252021A1
公开(公告)日:2015-09-10
申请号:US14640551
申请日:2015-03-06
Applicant: Helsinn Healthcare SA
Inventor: Claudio Giuliano , Silvina Garcia Rubio , Antoine Daina , Angelo Guainazzi , Claudio Pietra
IPC: C07D401/14 , C07D401/12 , C07D417/14 , C07D471/04 , C07D239/26 , C07D405/12 , C07D403/12 , C07D211/58 , C07D409/14
CPC classification number: C07F7/0812 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/96 , C07D213/00 , C07D239/26 , C07D241/12 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
Abstract translation: 公开了用于预防和/或治疗由生长素释放肽受体病理生理介导的疾病的化合物,组合物和方法。 化合物具有通式I或其药学上可接受的盐。
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公开(公告)号:US10577384B2
公开(公告)日:2020-03-03
申请号:US15889589
申请日:2018-02-06
Applicant: HELSINN HEALTHCARE SA
Inventor: Claudio Giuliano , Silvina Garcia Rubio , Antoine Daina , Angelo Guainazzi , Claudio Pietra
IPC: C07D211/58 , C07F7/08 , C07D401/14 , C07D401/12 , C07D417/14 , C07D409/14 , C07D239/26 , C07D405/12 , C07D403/12 , C07D471/04 , C07D401/06 , C07D211/60 , C07D211/94 , C07D211/96 , C07D213/00 , C07D241/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12
Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
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公开(公告)号:US20170145038A1
公开(公告)日:2017-05-25
申请号:US15368362
申请日:2016-12-02
Applicant: HELSINN HEALTHCARE SA
Inventor: Claudio Giuliano , Silvina Garcia Rubio , Antoine Daina , Angelo Guainazzi , Claudio Pietra
IPC: C07F7/08 , C07D401/12 , C07D401/14 , C07D417/14 , C07D409/14 , C07D239/26 , C07D405/12 , C07D405/14 , C07D403/12 , C07D241/12 , C07D409/12 , C07D417/12 , C07D413/12 , C07D471/04 , C07D211/58
CPC classification number: C07F7/0812 , C07D211/58 , C07D211/60 , C07D211/94 , C07D211/96 , C07D213/00 , C07D239/26 , C07D241/12 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
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