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公开(公告)号:US09233184B2
公开(公告)日:2016-01-12
申请号:US14326014
申请日:2014-07-08
发明人: Kiyomi Tsuruda , Shinji Yamasoto , Kouki Shoho , Masaru Nakanishi
IPC分类号: A61K9/70 , A61L15/16 , B32B27/04 , B32B27/12 , B32B25/02 , C08G61/02 , C08J3/00 , A61K6/083 , C08L15/00 , A61K6/00 , A61F13/00 , A61J15/00 , A61L15/44 , A61K31/045 , A61K31/618 , A61K31/695 , A61L15/24 , A61L15/58 , C09J4/00 , C09J101/00 , C09J201/00 , A61F15/00 , B32B7/12
CPC分类号: A61L15/44 , A61F13/00 , A61F15/00 , A61K9/7053 , A61K9/7076 , A61K31/045 , A61K31/618 , A61K31/695 , A61L15/24 , A61L15/58 , A61L2300/216 , B32B7/12 , Y10T428/28 , Y10T428/2852 , Y10T442/2738 , Y10T442/3561
摘要: An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.