公开(公告)号：US3871825A

公开(公告)日：1975-03-18

申请号：US44761074

申请日：1974-03-04

Applicant: HOFFMANN LA ROCHE

Inventor： LEIMGBURGER WILLY ,  WEIGELE MANFRED

IPC: C07C45/74 ,  C07C49/683 ,  C07C49/697 ,  C07C49/753 ,  C07C49/755 ,  C07C65/40 ,  C07C229/38 ,  C07D303/32 ,  C07D311/76 ,  C07D317/60 ,  C07D493/10 ,  G01N31/22 ,  G01N33/48 ,  G01N33/52 ,  G01N33/68 ,  G01N33/16

CPC classification number: C07D493/10 ,  C07C45/74 ,  C07C49/683 ,  C07C49/697 ,  C07C49/753 ,  C07C49/755 ,  C07C65/40 ,  C07C229/38 ,  C07D303/32 ,  C07D311/76 ,  C07D317/60 ,  G01N31/22 ,  G01N33/48 ,  G01N33/52 ,  G01N33/6809 ,  Y10T436/173845

Abstract: A novel class of reagents react with primary amine-containing compounds, preferably polypeptides and amino acids to form highly fluorescent products. This reaction serves as a basis for a rapid and highly sensitive assay method for primary amine-containing compounds.